Co-administration of a plasmid DNA encoding IL-15 improves long-term protection of a genetic vaccine against Trypanosoma cruzi - Wikidata - wikimedia - TriplyDB

Co-administration of a plasmid DNA encoding IL-15 improves long-term protection of a genetic vaccine against Trypanosoma cruzi

Co-administration of a plasmid DNA encoding IL-15 improves long-term protection of a genetic vaccine against Trypanosoma cruzi

http://www.wikidata.org/entity/Q33847435

about

The role of interleukin-15 in inflammation and immune responses to infection: implications for its therapeutic use Protective efficacy of Toxoplasma gondii calcium-dependent protein kinase 1 (TgCDPK1) adjuvated with recombinant IL-15 and IL-21 against experimental toxoplasmosis in mice Deficiency of antigen-specific B cells results in decreased Trypanosoma cruzi systemic but not mucosal immunity due to CD8 T cell exhaustion.A Two-Component DNA-Prime/Protein-Boost Vaccination Strategy for Eliciting Long-Term, Protective T Cell Immunity against Trypanosoma cruzi Technologies for enhanced efficacy of DNA vaccines.The Immune Response to Trypanosoma cruzi: Role of Toll-Like Receptors and Perspectives for Vaccine Development.Costimulatory Effects of an Immunodominant Parasite Antigen Paradoxically Prevent Induction of Optimal CD8 T Cell Protective Immunity.An immunoinformatic approach for identification of Trypanosoma cruzi HLA-A2-restricted CD8(+) T cell epitopes.CpG and interleukin-15 synergize to enhance IFN-γ production by activated CD8+ T cells A Novel Vaccine Approach for Chagas Disease Using Rare Adenovirus Serotype 48 Vectors.Comparison of the infectivity of Trypanosoma cruzi insect-derived metacyclic trypomastigotes after mucosal and cutaneous contaminative challenges.Advances and challenges towards a vaccine against Chagas disease.Gene-deleted live-attenuated Trypanosoma cruzi parasites as vaccines to protect against Chagas disease.Autoimmune pathogenesis of Chagas heart disease: looking back, looking ahead.Prophylactic and therapeutic DNA vaccines against Chagas disease.Recombinant rabies virus expressing IL-15 enhances immunogenicity through promoting the activation of dendritic cells in mice.Dying to protect: cell death and the control of T-cell homeostasis.Investigations of TB vaccine-induced mucosal protection in mice.Genetic Engineering of Co-producing Antigen and the Mucosal Adjuvant 3' 5'- cyclic di Adenosine Monophosphate (c-di-AMP) as a Design Strategy to Develop a Mucosal Vaccine Prototype

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P2860

Co-administration of a plasmid DNA encoding IL-15 improves long-term protection of a genetic vaccine against Trypanosoma cruzi

http://www.wikidata.org/entity/Q33847435

description

2011 nî lūn-bûn

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2011 թվականի մարտին հրատարակված գիտական հոդված

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Co-administration of a plasmid ...... cine against Trypanosoma cruzi

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JOURNAL.PNTD.0000983

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PLOS Neglected Tropical Diseases

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Co-administration of a plasmid ...... cine against Trypanosoma cruzi

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Azra Blazevic

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Christopher S Eickhoff

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Daniel F Hoft

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Jose R Vasconcelos

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Mauricio M Rodrigues

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Nicole L Sullivan

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Oscar Bruna-Romero

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P2860

IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells

Predominance of CD4 Th1 and CD8 Tc1 cells revealed by characterization of the cellular immune response generated by immunization with a DNA vaccine containing a Trypanosoma cruzi gene.

Involvement of CD4(+) Th1 cells in systemic immunity protective against primary and secondary challenges with Trypanosoma cruzi.

CD8+-T-cell-dependent control of Trypanosoma cruzi infection in a highly susceptible mouse strain after immunization with recombinant proteins based on amastigote surface protein 2.

The IL-15R alpha chain signals through association with Syk in human B cells.

Coadministration of an interleukin-12 gene and a Trypanosoma cruzi gene improves vaccine efficacy

Genetic immunization elicits antigen-specific protective immune responses and decreases disease severity in Trypanosoma cruzi infection

Blood donor screening for chagas disease--United States, 2006-2007.

Coadministration of HIV vaccine vectors with vaccinia viruses expressing IL-15 but not IL-2 induces long-lasting cellular immunity.

Anatomical route of invasion and protective mucosal immunity in Trypanosoma cruzi conjunctival infection.

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e983

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scholarly article

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10.1371/JOURNAL.PNTD.0000983

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50400111

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21408124

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Trypanosoma cruzi

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