Allele-specific genome editing and correction of disease-associated phenotypes in rats using the CRISPR-Cas platform
about
The Rise of CRISPR/Cas for Genome Editing in Stem CellsHematopoietic stem cell niche maintenance during homeostasis and regenerationAdvances on genetic rat models of epilepsy.From integrative genomics to systems genetics in the rat to link genotypes to phenotypesExploiting the CRISPR/Cas9 PAM Constraint for Single-Nucleotide Resolution InterventionsIdentifying genes for neurobehavioural traits in rodents: progress and pitfallsSpell Checking Nature: Versatility of CRISPR/Cas9 for Developing Treatments for Inherited Disorders.The utility of Apc-mutant rats in modeling human colon cancer.A mouse geneticist's practical guide to CRISPR applications.An Efficient Visual Screen for CRISPR/Cas9 Activity in Arabidopsis thaliana.CRISPR-engineered mosaicism rapidly reveals that loss of Kcnj13 function in mice mimics human disease phenotypes.Regenerative medicine: targeted genome editing in vivo.Reprogramming for cardiac regeneration.Cloning-free CRISPR/Cas system facilitates functional cassette knock-in in mice.Efficient Multiple Genome Modifications Induced by the crRNAs, tracrRNA and Cas9 Protein Complex in Zebrafish.CRISPR/Cas9 DNA cleavage at SNP-derived PAM enables both in vitro and in vivo KRT12 mutation-specific targeting.ssODN-mediated knock-in with CRISPR-Cas for large genomic regions in zygotes.Generation of Hprt-disrupted rat through mouse←rat ES chimerasNovel human mutation and CRISPR/Cas genome-edited mice reveal the importance of C-terminal domain of MSX1 in tooth and palate development.Utilising polymorphisms to achieve allele-specific genome editing in zebrafish.Germ line genome editing in clinics: the approaches, objectives and global society.Optimization of the production of knock-in alleles by CRISPR/Cas9 microinjection into the mouse zygote.Efficient gene targeting in mouse zygotes mediated by CRISPR/Cas9-protein.Modeling Disease In Vivo With CRISPR/Cas9.CRISPR/Cas9: molecular tool for gene therapy to target genome and epigenome in the treatment of lung cancer.Applications of CRISPR genome editing technology in drug target identification and validation.Genome engineering through CRISPR/Cas9 technology in the human germline and pluripotent stem cells.CrisprGE: a central hub of CRISPR/Cas-based genome editing.Epigenome Editing in the Brain.EHBP1L1 coordinates Rab8 and Bin1 to regulate apical-directed transport in polarized epithelial cells.From engineering to editing the rat genome.Selective disruption of an oncogenic mutant allele by CRISPR/Cas9 induces efficient tumor regressionMethods of epigenome editing for probing the function of genomic imprintingEffect of p22phox depletion on sympathetic regulation of blood pressure in SHRSP: evaluation in a new congenic strain.Gene Editing in Rat Embryonic Stem Cells to Produce In Vitro Models and In Vivo Reporters.Allele-specific locus binding and genome editing by CRISPR at the p16INK4a locus.Rabbit models for biomedical research revisited via genome editing approaches.Simple gamete preservation and artificial reproduction of mammals using micro-insemination techniques.Genome editing and assisted reproduction: curing embryos, society or prospective parents?Genome Editing of Rat.
P2860
Q26765852-D87B9F71-E503-429D-8D16-76AAABA17187Q26865273-BB0ABB37-FB68-45D2-A190-A393047FA2C9Q27024903-8473B94E-E84B-4045-8F90-97616158EF9CQ28077604-9234D068-85DD-4329-A227-29EE0C8F0915Q28552692-85A5A415-B5B2-4A02-BC50-861B62456869Q33588088-1AADDCF6-F2B3-4268-88C5-EB35C62FBF8FQ34045672-0F927503-91E3-4E73-A803-9166D0538DECQ34424145-73E0893F-E73A-4B22-9CDF-7D42582A8A58Q34441174-B4D33689-6ADF-4424-8F72-E42A5681C9CEQ34550792-480CA9AB-2ED1-4337-8EE1-86710928A916Q35065772-41DDE06D-E996-4C64-8A15-D017CD4A7C12Q35146211-289AD637-7E60-43C0-94E1-EA4868D47C06Q35156623-2E5423C6-33C2-4200-B426-0BDB18177DF2Q35552238-57C726E5-98E5-4776-B789-9E3FED2C5FE8Q35641056-02213C6F-587A-41D4-8742-75309B9F32A8Q36442476-440D0B61-0905-4E72-A0BA-1CC2811465E5Q36529479-50ABB5F5-650D-4170-BC5D-C962D01D2C6FQ36785241-6F17E12F-02FD-41A0-B57E-DEDB180EA903Q37472301-0989077D-FD34-4615-9543-76DEAF6E6A39Q37612421-C88B8069-433C-4214-8A82-4A6EB0F2FEC0Q37623660-E62C16D3-2C43-4197-9BF2-10918347B824Q37648801-54FE0A62-D9D6-4932-B1DE-0AEBF0EF05ABQ37699760-61DE056F-4385-45CE-8668-3C7DD41427F3Q38598073-01C38382-B2D2-41C6-81BF-ABA3CAA58CBDQ38614582-AE40ED41-362D-4987-9739-ADAB58A73839Q38708498-0E37CFFA-B0F7-4F9F-A2A7-6A454C628452Q38757108-F7E98DEF-3FDE-4BCA-980D-9EF0E098BD0DQ38859113-5CCDE1FC-A88D-4096-9F2E-6B72F1271782Q39317395-AB8341ED-B37E-4343-8864-A31328952150Q40034519-487581F7-B8DB-448F-BD54-009B3F9A1C35Q41504643-51B60585-4556-43C8-B961-ED6C3A779BF8Q41511092-F848A8B2-CD12-4A5C-BCBA-E31063105054Q41640900-4279147C-A2D7-42A1-A70A-C39E33D105DAQ42372427-B9DA8220-E5E0-48D3-AD2D-317F8349840CQ42376492-A5DE764F-D9D2-4458-80A6-546A1983C37DQ42397056-4EDADA0E-064B-47DA-8352-ACC986CF2600Q42668809-3075DE7C-E003-41C4-BD05-9FCEE9F393E5Q47408959-161F4D6B-D18C-4E3D-93DF-FE2C5B53F217Q47774735-9FB6A704-215A-4E26-9E18-6B14B5588005Q47992594-B2063E4D-A0F4-49F9-8C06-C8CB528E9C11
P2860
Allele-specific genome editing and correction of disease-associated phenotypes in rats using the CRISPR-Cas platform
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Allele-specific genome editing ...... using the CRISPR-Cas platform
@ast
Allele-specific genome editing ...... using the CRISPR-Cas platform
@en
type
label
Allele-specific genome editing ...... using the CRISPR-Cas platform
@ast
Allele-specific genome editing ...... using the CRISPR-Cas platform
@en
prefLabel
Allele-specific genome editing ...... using the CRISPR-Cas platform
@ast
Allele-specific genome editing ...... using the CRISPR-Cas platform
@en
P2093
P2860
P356
P1476
Allele-specific genome editing ...... using the CRISPR-Cas platform
@en
P2093
P2860
P2888
P356
10.1038/NCOMMS5240
P407
P577
2014-06-26T00:00:00Z
P5875
P6179
1004237023