Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in vivo - Wikidata - wikimedia - TriplyDB

Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in vivo

Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in vivo

http://www.wikidata.org/entity/Q33853087

about

Angptl4 protects against severe proinflammatory effects of saturated fat by inhibiting fatty acid uptake into mesenteric lymph node macrophages A critical role for the Sp1-binding sites in the transforming growth factor-beta-mediated inhibition of lipoprotein lipase gene expression in macrophages Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis Tissue-specific expression of human lipoprotein lipase in the vascular system affects vascular reactivity in transgenic mice Increased atherosclerosis in LDL receptor-null mice lacking ACAT1 in macrophages Increased atherosclerosis in myeloperoxidase-deficient mice PPARalpha deficiency reduces insulin resistance and atherosclerosis in apoE-null mice Lipid-laden partially-activated plasmacytoid and CD4(-)CD8α(+) dendritic cells accumulate in tissues in elderly mice Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in low density lipoprotein receptor-deficient mice Lipoprotein lipase, a key role in atherosclerosis?A novel role of Sp1 and Sp3 in the interferon-gamma -mediated suppression of macrophage lipoprotein lipase gene transcription.Combined adipocyte-macrophage fatty acid-binding protein deficiency improves metabolism, atherosclerosis, and survival in apolipoprotein E-deficient mice.Adipocyte fatty acid-binding protein, aP2, alters late atherosclerotic lesion formation in severe hypercholesterolemia Rescue of cardiomyopathy in peroxisome proliferator-activated receptor-alpha transgenic mice by deletion of lipoprotein lipase identifies sources of cardiac lipids and peroxisome proliferator-activated receptor-alpha activators Function and Therapeutic Potential of Mesenchymal Stem Cells in Atherosclerosis.Inhibition of cardiac lipoprotein utilization by transgenic overexpression of Angptl4 in the heart.N-3 vs. saturated fatty acids: effects on the arterial wall Mechanisms of lipase maturation.Efficient phagocytosis requires triacylglycerol hydrolysis by adipose triglyceride lipase Amelioration of hypertriglyceridemia with hypo-alpha-cholesterolemia in LPL deficient mice by hematopoietic cell-derived LPL.Endothelial-derived tissue factor pathway inhibitor regulates arterial thrombosis but is not required for development or hemostasis.Conditional disruption of the peroxisome proliferator-activated receptor gamma gene in mice results in lowered expression of ABCA1, ABCG1, and apoE in macrophages and reduced cholesterol efflux.Selective macrophage ascorbate deficiency suppresses early atherosclerosis.Macrophage adipose triglyceride lipase deficiency attenuates atherosclerotic lesion development in low-density lipoprotein receptor knockout mice Endothelial lipase is a major determinant of HDL level.The macrophage foam cell as a target for therapeutic intervention.Triglycerides and heart disease: still a hypothesis?Monocyte to macrophage differentiation goes along with modulation of the plasmalogen pattern through transcriptional regulation.Hepatic lipase expression in macrophages contributes to atherosclerosis in apoE-deficient and LCAT-transgenic mice.Deficiency of receptor-associated protein attenuates angiotensin II-induced atherosclerosis in hypercholesterolemic mice without influencing abdominal aortic aneurysms MicroRNA-590 Inhibits Lipoprotein Lipase Expression and Prevents Atherosclerosis in apoE Knockout Mice.Active autophagy but not lipophagy in macrophages with defective lipolysis.MicroRNA-27 Prevents Atherosclerosis by Suppressing Lipoprotein Lipase-Induced Lipid Accumulation and Inflammatory Response in Apolipoprotein E Knockout Mice Thematic review series: The immune system and atherogenesis. Cytokine regulation of macrophage functions in atherogenesis.Macrophage deficiency of Akt2 reduces atherosclerosis in Ldlr null mice Hydrolysis products generated by lipoprotein lipase and endothelial lipase differentially impact THP-1 macrophage cell signalling pathways.Macrophage lipoprotein lipase modulates the development of atherosclerosis but not adiposity.Macrophage IKKα Deficiency Suppresses Akt Phosphorylation, Reduces Cell Survival, and Decreases Early Atherosclerosis Macrophage EP4 deficiency increases apoptosis and suppresses early atherosclerosis.Cyclooxygenase products and atherosclerosis

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P2860

Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in vivo

http://www.wikidata.org/entity/Q33853087

description

1999 nî lūn-bûn

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1999 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի հունիսին հրատարակված գիտական հոդված

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1999年の論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年论文

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name

Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in vivo

@ast

Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in vivo

@en

type

label

Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in vivo

@ast

Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in vivo

@en

prefLabel

Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in vivo

@ast

Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in vivo

@en

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P1433

Journal of Clinical Investigation

P1476

Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in vivo

@en

P2093

C F Semenkovich

http://www.w3.org/2001/XMLSchema#string

K J Carter

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L A Gleaves

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M F Linton

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S Fazio

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V R Babaev

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P2860

Lipoprotein lipase enhances the binding of chylomicrons to low density lipoprotein receptor-related protein

Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet.

Lipoprotein lipase increases low density lipoprotein retention by subendothelial cell matrix.

Lipoprotein lipase is synthesized by macrophage-derived foam cells in human coronary atherosclerotic plaques.

Lipoprotein lipase-mediated uptake and degradation of low density lipoproteins by fibroblasts and macrophages.

Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes

Increased atherosclerosis in mice reconstituted with apolipoprotein E null macrophages

Quantitative assessment of atherosclerotic lesions in mice.

Catalytically inactive lipoprotein lipase expression in muscle of transgenic mice increases very low density lipoprotein uptake: direct evidence that lipoprotein lipase bridging occurs in vivo.

A common substitution (Asn291Ser) in lipoprotein lipase is associated with increased risk of ischemic heart disease.

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10.1172/JCI6117

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P433

12

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103

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1999-06-01T00:00:00Z

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12922289

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10377176

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P921

atherosclerosis

P932

408384

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