Transformation to continuous growth of primary human T lymphocytes by human T-cell leukemia virus type I X-region genes transduced by a Herpesvirus saimiri vector
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Human T-cell leukemia virus type 1 Tax activates transcription of the human fra-1 gene through multiple cis elements responsive to transmembrane signalsPhysical and functional interaction between the human T-cell lymphotropic virus type 1 Tax1 protein and the CCAAT binding protein NF-YViruses associated with human cancerSpecific TATAA and bZIP requirements suggest that HTLV-I Tax has transcriptional activity subsequent to the assembly of an initiation complexTwo discrete events, human T-cell leukemia virus type I Tax oncoprotein expression and a separate stress stimulus, are required for induction of apoptosis in T-cellsViral Inhibition of the IFN-Induced JAK/STAT Signalling Pathway: Development of Live Attenuated Vaccines by Mutation of Viral-Encoded IFN-AntagonistsMolecular Mechanisms of HTLV-1 Cell-to-Cell TransmissionActivation of the DNA Damage Response by RNA VirusesModulation of DNA damage and repair pathways by human tumour virusesMechanisms of pathogenesis induced by bovine leukemia virus as a model for human T-cell leukemia virusPossible involvement of interferon regulatory factor 4 (IRF4) in a clinical subtype of adult T-cell leukemiaLife, death, and tax: role of HTLV-I oncoprotein in genetic instability and cellular transformationEffect of transforming viruses on molecular mechanisms associated with cancerThe tax gene of human T-cell leukemia virus type 2 is essential for transformation of human T lymphocytesSegregation of NF-kappaB activation through NEMO/IKKgamma by Tax and TNFalpha: implications for stimulus-specific interruption of oncogenic signalingIL-2 independent transformation of a unique human T cell line, TY8-3, and its subclones by HTLV-I and -II.Functional interaction of HTLV-1 tax protein with the POZ domain of the transcriptional repressor BCL6.Discordance between bovine leukemia virus tax immortalization in vitro and oncogenicity in vivo.Induction of the WAF1/CIP1 protein and apoptosis in human T-cell leukemia virus type I-transformed lymphocytes after treatment with adriamycin by using a p53-independent pathway.Phosphorylation of the human T-cell leukemia virus type 1 transactivator tax on adjacent serine residues is critical for tax activationMechanisms of T-cell activation by human T-cell lymphotropic virus type I.HTLV-I Tax-dependent and -independent events associated with immortalization of human primary T lymphocytes.Herpesvirus saimiri.Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases.Human and simian T-cell leukemia viruses type 2 (HTLV-2 and STLV-2(pan-p)) transform T cells independently of Jak/STAT activation.Human T-cell lymphotropic/leukemia virus type 1 Tax abrogates p53-induced cell cycle arrest and apoptosis through its CREB/ATF functional domain.Activation of human T-cell leukemia virus type 1 tax gene expression in chronically infected T cells.Persistent activation of NF-kappaB by the tax transforming protein of HTLV-1: hijacking cellular IkappaB kinases.Identification of poly(ADP-ribose) polymerase as a transcriptional coactivator of the human T-cell leukemia virus type 1 Tax proteinInduction of adult T-cell leukemia-like lymphoproliferative disease and its inhibition by adoptive immunotherapy in T-cell-deficient nude rats inoculated with syngeneic human T-cell leukemia virus type 1-immortalized cells.Genetic evidence of a role for ATM in functional interaction between human T-cell leukemia virus type 1 Tax and p53.Evidence for NF-kappaB- and CBP-independent repression of p53's transcriptional activity by human T-cell leukemia virus type 1 Tax in mouse embryo and primary human fibroblasts.Infection of human synovial cells by human T cell lymphotropic virus type I. Proliferation and granulocyte/macrophage colony-stimulating factor production by synovial cellsCooperation between bovine leukaemia virus transactivator protein and Ha-ras oncogene product in cellular transformation.Human T-lymphotropic virus type I provirus and T-cell prolymphocytic leukemia.PCAF interacts with tax and stimulates tax transactivation in a histone acetyltransferase-independent mannerInactivation of p53 by human T-cell lymphotropic virus type 1 Tax requires activation of the NF-kappaB pathway and is dependent on p53 phosphorylation.Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300Inhibition of p53 transactivation function by the human T-cell lymphotropic virus type 1 Tax proteinHuman T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.
P2860
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P2860
Transformation to continuous growth of primary human T lymphocytes by human T-cell leukemia virus type I X-region genes transduced by a Herpesvirus saimiri vector
description
1989 nî lūn-bûn
@nan
1989 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年学术文章
@wuu
1989年学术文章
@zh-cn
1989年学术文章
@zh-hans
1989年学术文章
@zh-my
1989年学术文章
@zh-sg
1989年學術文章
@yue
name
Transformation to continuous g ...... y a Herpesvirus saimiri vector
@ast
Transformation to continuous g ...... y a Herpesvirus saimiri vector
@en
type
label
Transformation to continuous g ...... y a Herpesvirus saimiri vector
@ast
Transformation to continuous g ...... y a Herpesvirus saimiri vector
@en
prefLabel
Transformation to continuous g ...... y a Herpesvirus saimiri vector
@ast
Transformation to continuous g ...... y a Herpesvirus saimiri vector
@en
P2093
P2860
P921
P356
P1476
Transformation to continuous g ...... y a Herpesvirus saimiri vector
@en
P2093
B Fleckenstein
I Müller-Fleckenstein
J G Sodroski
M C Dokhelar
R Grassmann
P2860
P304
P356
10.1073/PNAS.86.9.3351
P407
P577
1989-05-01T00:00:00Z