Endoplasmic reticulum export, subcellular distribution, and fibril formation by Pmel17 require an intact N-terminal domain junction.

Endoplasmic reticulum export, subcellular distribution, and fibril formation by Pmel17 require an intact N-terminal domain junction.

Item
http://www.wikidata.org/entity/Q33855252
Effects of pH on aggregation kinetics of the repeat domain of a functional amyloid, Pmel17.Repeat domains of melanosome matrix protein Pmel17 orthologs form amyloid fibrils at the acidic melanosomal pH.Lysophospholipid-containing membranes modulate the fibril formation of the repeat domain of a human functional amyloid, pmel17.Proprotein convertases process Pmel17 during secretion.Toll-like receptor 2 and NLRP3 cooperate to recognize a functional bacterial amyloid, curliThe melanosomal protein PMEL17 as a target for antibody drug conjugate therapy in melanoma.Epithelial cells augment barrier function via activation of the Toll-like receptor 2/phosphatidylinositol 3-kinase pathway upon recognition of Salmonella enterica serovar Typhimurium curli fibrils in the gut.The Kringle-like Domain Facilitates Post-endoplasmic Reticulum Changes to Premelanosome Protein (PMEL) Oligomerization and Disulfide Bond Configuration and Promotes Amyloid Formation.Critical residues in the PMEL/Pmel17 N-terminus direct the hierarchical assembly of melanosomal fibrils.PMEL: a pigment cell-specific model for functional amyloid formationCD14 protein acts as an adaptor molecule for the immune recognition of Salmonella curli fibers.The PKD domain distinguishes the trafficking and amyloidogenic properties of the pigment cell protein PMEL and its homologue GPNMB.Melanosomal formation of PMEL core amyloid is driven by aromatic residues.Study of Exosomes Shed New Light on Physiology of Amyloidogenesis.Three tapasin docking sites in TAP cooperate to facilitate transporter stabilization and heterodimerization.Reversing the amyloid trend: Mechanism of fibril assembly and dissolution of the repeat domain from a human functional amyloid.
P2860

Endoplasmic reticulum export, subcellular distribution, and fibril formation by Pmel17 require an intact N-terminal domain junction.

Item
http://www.wikidata.org/entity/Q33855252
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Endoplasmic reticulum export, ...... ct N-terminal domain junction.
@ast
Endoplasmic reticulum export, ...... ct N-terminal domain junction.
@en
type
label
Endoplasmic reticulum export, ...... ct N-terminal domain junction.
@ast
Endoplasmic reticulum export, ...... ct N-terminal domain junction.
@en
prefLabel
Endoplasmic reticulum export, ...... ct N-terminal domain junction.
@ast
Endoplasmic reticulum export, ...... ct N-terminal domain junction.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932
P356
P1433
P1476
Endoplasmic reticulum export, ...... act N-terminal domain junction
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932