Inhibition of CRM1-mediated nuclear export of transcription factors by leukemogenic NUP98 fusion proteins. - Wikidata - wikimedia - TriplyDB

Inhibition of CRM1-mediated nuclear export of transcription factors by leukemogenic NUP98 fusion proteins.

Inhibition of CRM1-mediated nuclear export of transcription factors by leukemogenic NUP98 fusion proteins.

http://www.wikidata.org/entity/Q33855277

about

Structural Basis of Targeting the Exportin CRM1 in Cancer The nuclear envelope environment and its cancer connections.Dynein Light Chain 1 (DYNLT1) Interacts with Normal and Oncogenic Nucleoporins.Nuclear export signal within CALM is necessary for CALM-AF10-induced leukemia BMI1 suffers a degrading experience.Amino-terminal enhancer of split (AES) interacts with the oncoprotein NUP98-HOXA9 and enhances its transforming ability Regulation of NF-κB Oscillation by Nuclear Transport: Mechanisms Determining the Persistency and Frequency of Oscillation Functional analysis of the NUP98-CCDC28A fusion protein.The conserved Cockayne syndrome B-piggyBac fusion protein (CSB-PGBD3) affects DNA repair and induces both interferon-like and innate antiviral responses in CSB-null cells.The new nucleoporin: regulator of transcriptional repression and beyond Chromatin-prebound Crm1 recruits Nup98-HoxA9 fusion to induce aberrant expression of Hox cluster genes.A CALM-derived nuclear export signal is essential for CALM-AF10-mediated leukemogenesis.MLL is essential for NUP98-HOXA9-induced leukemia.A critical role for CRM1 in regulating HOXA gene transcription in CALM-AF10 leukemias.Leukemia-Associated Nup214 Fusion Proteins Disturb the XPO1-Mediated Nuclear-Cytoplasmic Transport Pathway and Thereby the NF-κB Signaling Pathway.Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice Chikungunya virus capsid protein contains nuclear import and export signals.Inhibition of the nuclear export of p65 and IQCG in leukemogenesis by NUP98-IQCG.Nucleoporin Gene Fusions and Hematopoietic Malignancies

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Inhibition of CRM1-mediated nuclear export of transcription factors by leukemogenic NUP98 fusion proteins.

http://www.wikidata.org/entity/Q33855277

description

2010 nî lūn-bûn

@nan

2010 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի մարտին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Inhibition of CRM1-mediated nu ...... mogenic NUP98 fusion proteins.

@ast

Inhibition of CRM1-mediated nu ...... mogenic NUP98 fusion proteins.

@en

type

label

Inhibition of CRM1-mediated nu ...... mogenic NUP98 fusion proteins.

@ast

Inhibition of CRM1-mediated nu ...... mogenic NUP98 fusion proteins.

@en

prefLabel

Inhibition of CRM1-mediated nu ...... mogenic NUP98 fusion proteins.

@ast

Inhibition of CRM1-mediated nu ...... mogenic NUP98 fusion proteins.

@en

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JBC.M109.048785

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Journal of Biological Chemistry

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Inhibition of CRM1-mediated nu ...... mogenic NUP98 fusion proteins.

@en

P2093

Akiko Takeda

http://www.w3.org/2001/XMLSchema#string

Anmaar M Abdul-Nabi

http://www.w3.org/2001/XMLSchema#string

Nabeel R Yaseen

http://www.w3.org/2001/XMLSchema#string

Nayan J Sarma

http://www.w3.org/2001/XMLSchema#string

P2860

RAE1 is a shuttling mRNA export factor that binds to a GLEBS-like NUP98 motif at the nuclear pore complex through multiple domains

The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88

Nucleoporins nup98 and nup214 participate in nuclear export of human immunodeficiency virus type 1 Rev

CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity

Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

Two distinct classes of Ran-binding sites on the nucleoporin Nup-358

Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype.

The nucleoporin Nup98 is a site for GDP/GTP exchange on ran and termination of karyopherin beta 2-mediated nuclear import

The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1

The inv(11)(p15q22) chromosome translocation of de novo and therapy-related myeloid malignancies results in fusion of the nucleoporin gene, NUP98, with the putative RNA helicase gene, DDX10

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16248-16257

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scholarly article

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10.1074/JBC.M109.048785

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21

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285

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2010-03-16T00:00:00Z

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20233715

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2871492

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