Novel splice variants of cyclin E with altered substrate specificity.
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A dual role of cyclin E in cell proliferation and apoptosis may provide a target for cancer therapyChromosomal instability and lack of cyclin E regulation in hCdc4 mutant human breast cancer cellsNovel Molecular Markers for Breast CancerTargeting cyclin-dependent kinases in human cancers: from small molecules to Peptide inhibitorsCyclin D1: polymorphism, aberrant splicing and cancer riskGenome-wide analysis of core cell cycle genes in Arabidopsis.ERK regulates calpain 2-induced androgen receptor proteolysis in CWR22 relapsed prostate tumor cell linesDecreased proliferation kinetics of mouse myoblasts overexpressing FRG1.Tumor-specific proteolytic processing of cyclin E generates hyperactive lower-molecular-weight formsLMW-E/CDK2 deregulates acinar morphogenesis, induces tumorigenesis, and associates with the activated b-Raf-ERK1/2-mTOR pathway in breast cancer patientsProteolytic cleavage of cyclin E leads to inactivation of associated kinase activity and amplification of apoptosis in hematopoietic cells.An intron-retaining splice variant of human cyclin A2, expressed in adult differentiated tissues, induces a G1/S cell cycle arrest in vitro.Cell cyclins: triggering elements of cancer or not?MicroRNA-16 modulates HuR regulation of cyclin E1 in breast cancer cellsAmong B-type cyclins only CLB5 and CLB6 promote premeiotic S phase in Saccharomyces cerevisiaeIL-17A and its homologs IL-25/IL-17E recruit the c-RAF/S6 kinase pathway and the generation of pro-oncogenic LMW-E in breast cancer cells.Three-dimensional collagen represses cyclin E1 via β1 integrin in invasive breast cancer cells.Hbo1 is a cyclin E/CDK2 substrate that enriches breast cancer stem-like cells.Targeting low molecular weight cyclin E (LMW-E) in breast cancer.Novel role for cyclin-dependent kinase 2 in neuregulin-induced acetylcholine receptor epsilon subunit expression in differentiated myotubes.Activation of cyclin-dependent kinase 2 by full length and low molecular weight forms of cyclin E in breast cancer cells.Retinoic acid protects against hyperoxia-mediated cell-cycle arrest of lung alveolar epithelial cells by preserving late G1 cyclin activities.Ectopic expression of cyclin E in estrogen responsive cells abrogates antiestrogen mediated growth arrest.
P2860
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P2860
Novel splice variants of cyclin E with altered substrate specificity.
description
2000 nî lūn-bûn
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2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
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2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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name
Novel splice variants of cyclin E with altered substrate specificity.
@ast
Novel splice variants of cyclin E with altered substrate specificity.
@en
type
label
Novel splice variants of cyclin E with altered substrate specificity.
@ast
Novel splice variants of cyclin E with altered substrate specificity.
@en
prefLabel
Novel splice variants of cyclin E with altered substrate specificity.
@ast
Novel splice variants of cyclin E with altered substrate specificity.
@en
P2860
P356
P1476
Novel splice variants of cyclin E with altered substrate specificity.
@en
P2093
D C Porter
K Keyomarsi
P2860
P356
10.1093/NAR/28.23.E101
P407
P577
2000-12-01T00:00:00Z