Uncoupling antisense-mediated silencing and DNA methylation in the imprinted Gnas cluster. - Wikidata - wikimedia - TriplyDB

Uncoupling antisense-mediated silencing and DNA methylation in the imprinted Gnas cluster.

Uncoupling antisense-mediated silencing and DNA methylation in the imprinted Gnas cluster.

http://www.wikidata.org/entity/Q33859387

about

Genomic imprinting in mammals The GNAS complex locus and human diseases associated with loss-of-function mutations or epimutations within this imprinted gene New insights into establishment and maintenance of DNA methylation imprints in mammals Regulatory links between imprinted genes: evolutionary predictions and consequences A downstream CpG island controls transcript initiation and elongation and the methylation state of the imprinted Airn macro ncRNA promoter Maternal inheritance of the Gnas cluster mutation Ex1A-T affects size, implicating NESP55 in growth Individual common variants exert weak effects on the risk for autism spectrum disorders Gene regulation by the act of long non-coding RNA transcription H19 lncRNA controls gene expression of the Imprinted Gene Network by recruiting MBD1.An RNA-Seq strategy to detect the complete coding and non-coding transcriptome including full-length imprinted macro ncRNAs.Postnatal changes in the expression pattern of the imprinted signalling protein XLαs underlie the changing phenotype of deficient mice.The role of genomic imprinting in biology and disease: an expanding view.Transcription driven somatic DNA methylation within the imprinted Gnas cluster Imprinted expression in cystic embryoid bodies shows an embryonic and not an extra-embryonic pattern MicroRNAs 296 and 298 are imprinted and part of the GNAS/Gnas cluster and miR-296 targets IKBKE and Tmed9.Chromatin-Mediated Reversible Silencing of Sense-Antisense Gene Pairs in Embryonic Stem Cells Is Consolidated upon Differentiation.Tet-mediated imprinting erasure in H19 locus following reprogramming of spermatogonial stem cells to induced pluripotent stem cells.Mechanisms of long range silencing by imprinted macro non-coding RNAs.New Cross-Talk Layer between Ultraconserved Non-Coding RNAs, MicroRNAs and Polycomb Protein YY1 in Bladder Cancer Non-Coding RNAs at the Gnas and Snrpn-Ube3a Imprinted Gene Loci and Their Involvement in Hereditary Disorders.Imprinting and expression of Dio3os mirrors Dio3 in rat Tissue-specific patterns of allelically-skewed DNA methylation.Epigenetics and phenotypic variability: some interesting insights from birds Non-polyadenylated transcription in embryonic stem cells reveals novel non-coding RNA related to pluripotency and differentiation Epigenetic and transcriptional features of the novel human imprinted lncRNA GPR1AS suggest it is a functional ortholog to mouse Zdbf2linc Noisy silence: non-coding RNA and heterochromatin formation at repetitive elements.RNA interference in mammalian DNA methylation.Macro lncRNAs: a new layer of cis-regulatory information in the mammalian genome.The non-coding skin: exploring the roles of long non-coding RNAs in epidermal homeostasis and disease.Long noncoding RNA: significance and potential in skin biology.Non-coding RNAs: Classification, Biology and Functioning.Genetic Studies on Mammalian DNA Methyltransferases.TINCR, staufen1, and cellular differentiation.Epigenetics Europe conference. Munich, Germany, 8-9 September 2011.Long Noncoding RNAs in Mammalian Development and Diseases.Antisense Activity across the Nesp Promoter is Required for Nespas-Mediated Silencing in the Imprinted Gnas Cluster.Imprinted DNA methylation reprogramming during early mouse embryogenesis at theGpr1-Zdbf2locus is linked to longcis-intergenic transcription Genome organization and chromatin analysis identify transcriptional downregulation of insulin-like growth factor signaling as a hallmark of aging in developing B cells

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Uncoupling antisense-mediated silencing and DNA methylation in the imprinted Gnas cluster.

http://www.wikidata.org/entity/Q33859387

description

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2011 թվականի մարտին հրատարակված գիտական հոդված

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2011年の論文

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Uncoupling antisense-mediated ...... in the imprinted Gnas cluster.

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Uncoupling antisense-mediated ...... in the imprinted Gnas cluster.

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Uncoupling antisense-mediated ...... in the imprinted Gnas cluster.

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JOURNAL.PGEN.1001347

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Uncoupling antisense-mediated silencing and DNA methylation in the imprinted Gnas cluster

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Christine M Williamson

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Claire Dawson

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Colin V Beechey

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Jo Peters

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Lydia Teboul

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Martin Fray

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Simon T Ball

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T Neil Dear

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The genetic signatures of noncoding RNAs

Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice

KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints

Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation

Allele-specific histone lysine methylation marks regulatory regions at imprinted mouse genes.

Elongation of the Kcnq1ot1 transcript is required for genomic imprinting of neighboring genes

Silencing by imprinted noncoding RNAs: is transcription the answer?

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA

Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA

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10.1371/JOURNAL.PGEN.1001347

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50940464

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21455290

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DNA methylation

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3063750

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