A theoretical framework for gene induction and experimental comparisons.
about
Glucocorticoid-independent modulation of GR activity: Implications for immunotherapyPA1 protein, a new competitive decelerator acting at more than one step to impede glucocorticoid receptor-mediated transactivationA model for aryl hydrocarbon receptor-activated gene expression shows potency and efficacy changes and predicts squelching due to competition for transcription co-activatorsResearch resource: modulators of glucocorticoid receptor activity identified by a new high-throughput screening assay.Deducing the temporal order of cofactor function in ligand-regulated gene transcription: theory and experimental verification.Glucocorticoid receptor cofactors as therapeutic targets.Impact of glucocorticoid receptor density on ligand-independent dimerization, cooperative ligand-binding and basal priming of transactivation: a cell culture model.A framework for modelling gene regulation which accommodates non-equilibrium mechanisms.Ligand binding domain mutations of the glucocorticoid receptor selectively modify the effects with, but not binding of, cofactors.Kinetically-defined component actions in gene repressionInferring mechanisms from dose-response curvesThe road less traveled: new views of steroid receptor action from the path of dose-response curves.Separate regions of glucocorticoid receptor, coactivator TIF2, and comodulator STAMP modify different parameters of glucocorticoid-mediated gene induction.The hypersensitive glucocorticoid response specifically regulates period 1 and expression of circadian genesWhat do expression dynamics tell us about the mechanism of transcription?Kinetically Defined Mechanisms and Positions of Action of Two New Modulators of Glucocorticoid Receptor-regulated Gene Induction.Identification of location and kinetically defined mechanism of cofactors and reporter genes in the cascade of steroid-regulated transactivation.Direct observation of frequency modulated transcription in single cells using light activation.Variable steroid receptor responses: Intrinsically disordered AF1 is the key.Eukaryotic transcriptional dynamics: from single molecules to cell populations.A conserved protein motif is required for full modulatory activity of negative elongation factor subunits NELF-A and NELF-B in modifying glucocorticoid receptor-regulated gene induction properties.Minireview: dynamic structures of nuclear hormone receptors: new promises and challenges.More than meets the dimer: What is the quaternary structure of the glucocorticoid receptor?A kinase-independent activity of Cdk9 modulates glucocorticoid receptor-mediated gene induction.The use of mode of action information in risk assessment: quantitative key events/dose-response framework for modeling the dose-response for key events.Corticosteroid receptor signalling modes and stress adaptation in the brain.Unconventional Coupling between Ligand Recognition and Allosteric Control in the Multidrug Resistance Gene Regulator, BmrR.Quantitative analysis of the bidirectional viral G-protein-coupled receptor and lytic latency-associated nuclear antigen promoter of Kaposi's sarcoma-associated herpesvirus.Theory of partial agonist activity of steroid hormones.Inferring gene regulatory networks from single-cell data: a mechanistic approach.An Approach to Greater Specificity for Glucocorticoids.Transcription factor target site search and gene regulation in a background of unspecific binding sites
P2860
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P2860
A theoretical framework for gene induction and experimental comparisons.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
A theoretical framework for gene induction and experimental comparisons.
@ast
A theoretical framework for gene induction and experimental comparisons.
@en
type
label
A theoretical framework for gene induction and experimental comparisons.
@ast
A theoretical framework for gene induction and experimental comparisons.
@en
prefLabel
A theoretical framework for gene induction and experimental comparisons.
@ast
A theoretical framework for gene induction and experimental comparisons.
@en
P2093
P2860
P356
P1476
A theoretical framework for gene induction and experimental comparisons.
@en
P2093
Benjamin L Kagan
Carson C Chow
John A Blackford
Karen M Ong
S Stoney Simons
P2860
P304
P356
10.1073/PNAS.0911095107
P407
P577
2010-03-29T00:00:00Z