In vitro amplification of misfolded prion protein using lysate of cultured cells.
about
Preclinical detection of variant CJD and BSE prions in blood.Human prion protein sequence elements impede cross-species chronic wasting disease transmission.A proposed mechanism for the promotion of prion conversion involving a strictly conserved tyrosine residue in the β2-α2 loop of PrPC.Abrogation of complex glycosylation by swainsonine results in strain- and cell-specific inhibition of prion replication.PrPSc formation and clearance as determinants of prion tropism.Slow spontaneous α-to-β structural conversion in a non-denaturing neutral condition reveals the intrinsically disordered property of the disulfide-reduced recombinant mouse prion protein.Cell-specific susceptibility to prion strains is a property of the intact cell.PrP Knockout Cells Expressing Transmembrane PrP Resist Prion InfectionA transfectant RK13 cell line permissive to classical caprine scrapie prion propagationEvaluation of infective property of recombinant prion protein amyloids in cultured cells overexpressing cellular prion protein.Glycoform-independent prion conversion by highly efficient, cell-based, protein misfolding cyclic amplification.Asparagine and glutamine ladders promote cross-species prion conversion.Protocol for further laboratory investigations into the distribution of infectivity of Atypical BSE
P2860
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P2860
In vitro amplification of misfolded prion protein using lysate of cultured cells.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
In vitro amplification of misfolded prion protein using lysate of cultured cells.
@ast
In vitro amplification of misfolded prion protein using lysate of cultured cells.
@en
type
label
In vitro amplification of misfolded prion protein using lysate of cultured cells.
@ast
In vitro amplification of misfolded prion protein using lysate of cultured cells.
@en
prefLabel
In vitro amplification of misfolded prion protein using lysate of cultured cells.
@ast
In vitro amplification of misfolded prion protein using lysate of cultured cells.
@en
P2093
P2860
P1433
P1476
In vitro amplification of misfolded prion protein using lysate of cultured cells.
@en
P2093
Charles E Mays
Chongsuk Ryou
Glenn C Telling
Hae-Eun Kang
Jifeng Bian
Jihyun Yeom
Vadim Khaychuk
Younghwan Kim
P2860
P304
P356
10.1371/JOURNAL.PONE.0018047
P407
P50
P577
2011-03-28T00:00:00Z