The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa-associated lymphoid tissue lymphomas.
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Molecular cloning of Porimin, a novel cell surface receptor mediating oncotic cell deathcIAP2 is a ubiquitin protein ligase for BCL10 and is dysregulated in mucosa-associated lymphoid tissue lymphomasAPI2-MALT1 oncoprotein promotes lymphomagenesis via unique program of substrate ubiquitination and proteolysisInfectious Aetiology of Marginal Zone Lymphoma and Role of Anti-Infective TherapyHelicobacter pylori-negative gastric mucosa-associated lymphoid tissue lymphomas: A reviewMolecular Pathogenesis of MALT LymphomaTargeting the apoptosis pathway in hematologic malignanciesFAS (CD95) mutations are rare in gastric MALT lymphoma but occur more frequently in primary gastric diffuse large B-cell lymphomaThe protein kinase C-responsive inhibitory domain of CARD11 functions in NF-kappaB activation to regulate the association of multiple signaling cofactors that differentially depend on Bcl10 and MALT1 for association.Fluorescence in situ hybridization (FISH) analysis of primary ocular adnexal MALT lymphomaClassification of lymphoid neoplasms: the microscope as a tool for disease discovery.Auto-ubiquitination-induced degradation of MALT1-API2 prevents BCL10 destabilization in t(11;18)(q21;q21)-positive MALT lymphoma.Primary gallbladder small lymphocytic lymphoma as a rare postcholecystectomy finding.Non-canonical NF-κB activation and abnormal B cell accumulation in mice expressing ubiquitin protein ligase-inactive c-IAP2.The CBM signalosome: potential therapeutic target for aggressive lymphoma?Oncogenic activation of NF-kappaB.CARMA1-mediated NF-kappaB and JNK activation in lymphocytes.Pathogenetic importance and therapeutic implications of NF-κB in lymphoid malignancies.Molecular diagnostic approach to non-Hodgkin's lymphoma.Pharmacological inhibition of MALT1 protease activity protects mice in a mouse model of multiple sclerosis.Oligomeric structure of the MALT1 tandem Ig-like domains.Identification of chromosomal translocation hotspots via scan statisticsMechanism and specificity of the human paracaspase MALT1.B-cell receptor signaling as a driver of lymphoma development and evolution.MALT1 auto-proteolysis is essential for NF-κB-dependent gene transcription in activated lymphocytes.Overexpression of miR-142-5p and miR-155 in gastric mucosa-associated lymphoid tissue (MALT) lymphoma resistant to Helicobacter pylori eradication.The API2-MALT1 fusion exploits TNFR pathway-associated RIP1 ubiquitination to promote oncogenic NF-κB signaling.Helicobacter and gastric MALT lymphoma.Cell kinetics and cell cycle regulation in lymphomas.Activation of NF-kappaB and inhibition of p53-mediated apoptosis by API2/mucosa-associated lymphoid tissue 1 fusions promote oncogenesis.Chromosomal translocation t(11;18)(q21;q21) in gastrointestinal mucosa associated lymphoid tissue lymphomaCombined applications of fine needle aspiration cytology and flow cytometric immunphenotyping for diagnosis and classification of non Hodgkin lymphomaNF-κB and cancer: a paradigm of Yin-Yang.API2-MALT1 fusion transcripts involved in mucosa-associated lymphoid tissue lymphoma: multiplex RT-PCR detection using formalin-fixed paraffin-embedded specimensMucosa-associated lymphoid tissue lymphomas with t(11;18)(q21;q21) and mucosa-associated lymphoid tissue lymphomas with aneuploidy develop along different pathogenetic pathways.API2-MALT1 fusion defines a distinctive clinicopathologic subtype in pulmonary extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue.Primary thymic extranodal marginal-zone B-cell lymphoma of mucosa-associated lymphoid tissue type exhibits distinctive clinicopathological and molecular features.API2-MALT1 chimeric transcripts involved in mucosa-associated lymphoid tissue type lymphoma predict heterogeneous products.Incidence and subtype specificity of API2-MALT1 fusion translocations in extranodal, nodal, and splenic marginal zone lymphomas.Novel genomic imbalances in B-cell splenic marginal zone lymphomas revealed by comparative genomic hybridization and cytogenetics.
P2860
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P2860
The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa-associated lymphoid tissue lymphomas.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The apoptosis inhibitor gene A ...... ted lymphoid tissue lymphomas.
@ast
The apoptosis inhibitor gene A ...... ted lymphoid tissue lymphomas.
@en
type
label
The apoptosis inhibitor gene A ...... ted lymphoid tissue lymphomas.
@ast
The apoptosis inhibitor gene A ...... ted lymphoid tissue lymphomas.
@en
prefLabel
The apoptosis inhibitor gene A ...... ted lymphoid tissue lymphomas.
@ast
The apoptosis inhibitor gene A ...... ted lymphoid tissue lymphomas.
@en
P2093
P1433
P1476
The apoptosis inhibitor gene A ...... ted lymphoid tissue lymphomas.
@en
P2093
De Wolf-Peeters C
Dierlamm J
Hagemeijer A
Hernandez JM
Hossfeld DK
Stefanova-Ouzounova M
Van den Berghe H
Wlodarska I
P304
P407
P577
1999-06-01T00:00:00Z