Molecular basis for the inactivation of Ca2+- and voltage-dependent BK channels in adrenal chromaffin cells and rat insulinoma tumor cells.
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A neuronal beta subunit (KCNMB4) makes the large conductance, voltage- and Ca2+-activated K+ channel resistant to charybdotoxin and iberiotoxinElimination of fast inactivation in Kv4 A-type potassium channels by an auxiliary subunit domainInactivation of BK channels by the NH2 terminus of the beta2 auxiliary subunit: an essential role of a terminal peptide segment of three hydrophobic residuesInactivation of BK channels mediated by the NH(2) terminus of the beta3b auxiliary subunit involves a two-step mechanism: possible separation of binding and blockadeGating properties conferred on BK channels by the beta3b auxiliary subunit in the absence of its NH(2)- and COOH terminiSlo3 K+ channels: voltage and pH dependence of macroscopic currentsStructural determinants for functional coupling between the beta and alpha subunits in the Ca2+-activated K+ (BK) channelThe Hodgkin-Huxley heritage: from channels to circuitsOn benzofuroindole analogues as smooth muscle relaxantsRapidly inactivating and non-inactivating calcium-activated potassium currents in frog saccular hair cellsInteractions between beta subunits of the KCNMB family and Slo3: beta4 selectively modulates Slo3 expression and functionFunctional effects of auxiliary beta4-subunit on rat large-conductance Ca(2+)-activated K(+) channelFunctional coupling between the Kv1.1 channel and aldoketoreductase Kvbeta1Steady-state and closed-state inactivation properties of inactivating BK channelsBK Channels in the Central Nervous System.Structural basis for calcium and magnesium regulation of a large conductance calcium-activated potassium channel with β1 subunitsα-Catulin CTN-1 is required for BK channel subcellular localization in C. elegans body-wall muscle cells.A novel auxiliary subunit critical to BK channel function in Caenorhabditis elegans.Genetic targeting and physiological features of VGLUT3+ amacrine cells.Lysine-rich extracellular rings formed by hbeta2 subunits confer the outward rectification of BK channels.Species-specific Differences among KCNMB3 BK beta3 auxiliary subunits: some beta3 N-terminal variants may be primate-specific subunits.Regulation of large conductance Ca2+-activated K+ (BK) channel β1 subunit expression by muscle RING finger protein 1 in diabetic vessels.Glycine311, a determinant of paxilline block in BK channels: a novel bend in the BK S6 helix.Modeling hair cell tuning by expression gradients of potassium channel beta subunits.Bilayer thickness modulates the conductance of the BK channel in model membranes.Knockout of the BK β2 subunit abolishes inactivation of BK currents in mouse adrenal chromaffin cells and results in slow-wave burst activity.Stereospecific binding of a disordered peptide segment mediates BK channel inactivation.Knockout of the BK β2 subunit reveals the importance of accessorizing your channel.Paxilline inhibits BK channels by an almost exclusively closed-channel block mechanism.Defining the BK channel domains required for beta1-subunit modulation.Orientations and proximities of the extracellular ends of transmembrane helices S0 and S4 in open and closed BK potassium channels.Western blot analysis of BK channel β1-subunit expression should be interpreted cautiously when using commercially available antibodies.Modulation of BK channel gating by the ß2 subunit involves both membrane-spanning and cytoplasmic domains of Slo1.Two distinct effects of PIP2 underlie auxiliary subunit-dependent modulation of Slo1 BK channels.Molecular mechanism underlying β1 regulation in voltage- and calcium-activated potassium (BK) channels.Identification of large conductance calcium activated potassium channel accessory beta4 subunit in rat and mouse bladder smooth muscle.Mechanistic details of BK channel inhibition by the intermediate conductance, Ca2+-activated K channel.Regulation of Voltage-Activated K(+) Channel Gating by Transmembrane β Subunits.Reconstruction of Cell Surface Densities of Ion Pumps, Exchangers, and Channels from mRNA Expression, Conductance Kinetics, Whole-Cell Calcium, and Current-Clamp Voltage Recordings, with an Application to Human Uterine Smooth Muscle Cells.Reactive oxygen species signaling facilitates FOXO-3a/FBXO-dependent vascular BK channel β1 subunit degradation in diabetic mice.
P2860
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P2860
Molecular basis for the inactivation of Ca2+- and voltage-dependent BK channels in adrenal chromaffin cells and rat insulinoma tumor cells.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Molecular basis for the inacti ...... nd rat insulinoma tumor cells.
@ast
Molecular basis for the inacti ...... nd rat insulinoma tumor cells.
@en
type
label
Molecular basis for the inacti ...... nd rat insulinoma tumor cells.
@ast
Molecular basis for the inacti ...... nd rat insulinoma tumor cells.
@en
prefLabel
Molecular basis for the inacti ...... nd rat insulinoma tumor cells.
@ast
Molecular basis for the inacti ...... nd rat insulinoma tumor cells.
@en
P2093
P1476
Molecular basis for the inacti ...... nd rat insulinoma tumor cells.
@en
P2093
P304
P407
P577
1999-07-01T00:00:00Z