Defects in the low density lipoprotein receptor gene affect lipoprotein (a) levels: multiplicative interaction of two gene loci associated with premature atherosclerosis.
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Hypothesis: lipoprotein(a) is a surrogate for ascorbateThe low density lipoprotein receptor is not required for normal catabolism of Lp(a) in humansVariation in lipoprotein(a) concentrations among individuals with the same apolipoprotein (a) isoform is determined by the rate of lipoprotein(a) productionThe interaction between coagulation factor 2 receptor and interleukin 6 haplotypes increases the risk of myocardial infarction in men.Elevated plasma concentrations of lipoprotein(a) in patients with end-stage renal disease are not related to the size polymorphism of apolipoprotein(a)Relationship between apolipoprotein(a) phenotype, lipoprotein(a) concentration in plasma, and low density lipoprotein receptor function in a large kindred with familial hypercholesterolemia due to the pro664----leu mutation in the LDL receptor gene.Overexpression of human low density lipoprotein receptors leads to accelerated catabolism of Lp(a) lipoprotein in transgenic miceMolecular basis of apolipoprotein (a) isoform size heterogeneity as revealed by pulsed-field gel electrophoresisHormonal influences on lipoprotein(a) metabolism.Lipoprotein (a) and other Lipid Profile in Patients with Thrombotic Stroke: Is it a Reliable Marker?Expressed hypervariable polymorphism of apolipoprotein (a).The Gordon Wilson Lecture. Plasma cholesterol: atherogenesis and mortality.Apolipoprotein(a) phenotypes, Lp(a) concentration and plasma lipid levels in relation to coronary heart disease in a Chinese population: evidence for the role of the apo(a) gene in coronary heart disease.Hormonal regulation of serum Lp (a) levels. Opposite effects after estrogen treatment and orchidectomy in males with prostatic carcinomaDistribution of apolipoprotein(a) in the plasma from patients with lipoprotein lipase deficiency and with type III hyperlipoproteinemia. No evidence for a triglyceride-rich precursor of lipoprotein(a)Lipoprotein(a): biology and clinical importanceThe role of lecithin: cholesterol acyltransferase for lipoprotein (a) assembly. Structural integrity of low density lipoproteins is a prerequisite for Lp(a) formation in human plasma.Transgenic rabbit models for studying human cardiovascular diseases.Sib-pair analysis detects elevated Lp(a) levels and large variation of Lp(a) concentration in subjects with familial defective ApoBLipoprotein (a). Heterogeneity and biological relevance.Lipoprotein(a): resurrected by genetics.Structure, function, and genetics of lipoprotein (a).Lipoprotein(a) in health and disease.Lipoprotein (a): a possible link between lipoprotein metabolism and thrombosis.Large rearrangements of the LDL receptor gene and lipid profile in a FH Spanish population.Role of various tissues in apo(a) fragmentation and excretion of fragments by the kidney.Lack of genetic linkage evidence for a trans-acting factor having a large effect on plasma lipoprotein[a] levels in African Americans.Standardization and clinical management of lipoprotein(a) measurements.Lipoprotein [a] is cleared from the plasma primarily by the liver in a process mediated by apolipoprotein [a].High lipoprotein(a) levels with predominance of high molecular weight apo(a) isoforms in patients with pulmonary embolism.Therapeutic potential of mipomersen in the management of familial hypercholesterolaemia.Lipoprotein(a) in patients with hepatocellular carcinoma and portal vein thrombosis.Serum distribution of lipoprotein(a) in African Americans and Nigerians: potential evidence for a genotype-environmental effect.Racial variation of cord plasma lipoprotein(a) levels in relation to coronary risk level: a study in three ethnic groups in Singapore.Influence of apolipoprotein E genotypes on plasma lipid and lipoprotein concentrations: results from a segregation analysis in pedigrees with molecularly defined familial hypercholesterolemia.
P2860
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P2860
Defects in the low density lipoprotein receptor gene affect lipoprotein (a) levels: multiplicative interaction of two gene loci associated with premature atherosclerosis.
description
1989 nî lūn-bûn
@nan
1989 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Defects in the low density lip ...... ith premature atherosclerosis.
@ast
Defects in the low density lip ...... ith premature atherosclerosis.
@en
type
label
Defects in the low density lip ...... ith premature atherosclerosis.
@ast
Defects in the low density lip ...... ith premature atherosclerosis.
@en
prefLabel
Defects in the low density lip ...... ith premature atherosclerosis.
@ast
Defects in the low density lip ...... ith premature atherosclerosis.
@en
P2093
P2860
P921
P356
P1476
Defects in the low density lip ...... ith premature atherosclerosis.
@en
P2093
Boerwinkle E
Dieplinger H
Hoppichler F
Thompson G
Utermann G
P2860
P304
P356
10.1073/PNAS.86.11.4171
P407
P577
1989-06-01T00:00:00Z