A pilot study to evaluate the safety and efficacy of the long-acting interleukin-1 inhibitor rilonacept (interleukin-1 Trap) in patients with familial cold autoinflammatory syndrome. - Wikidata - wikimedia - TriplyDB

A pilot study to evaluate the safety and efficacy of the long-acting interleukin-1 inhibitor rilonacept (interleukin-1 Trap) in patients with familial cold autoinflammatory syndrome.

A pilot study to evaluate the safety and efficacy of the long-acting interleukin-1 inhibitor rilonacept (interleukin-1 Trap) in patients with familial cold autoinflammatory syndrome.

http://www.wikidata.org/entity/Q33871994

about

Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*)A clear and present danger: inflammasomes DAMPing down disorders of pregnancy Beyond the NLRP3 inflammasome: autoinflammatory diseases reach adolescence Evasion of inflammasome activation by microbial pathogens Cryopyrin-associated periodic syndromes: otolaryngologic and audiologic manifestations Potential of IL-1, IL-18 and Inflammasome Inhibition for the Treatment of Inflammatory Skin Diseases.Treatment of Muckle-Wells syndrome: analysis of two IL-1-blocking regimens Targeting cytokines in inflammatory diseases: focus on interleukin-1-mediated autoinflammation MRP8 and MRP14, phagocyte-specific danger signals, are sensitive biomarkers of disease activity in cryopyrin-associated periodic syndromes Caspase functions in cell death and disease.Autoinflammation: the prominent role of IL-1 in monogenic autoinflammatory diseases and implications for common illnesses.A 24-month open-label study of canakinumab in neonatal-onset multisystem inflammatory disease.Phenotypic and genotypic characteristics of cryopyrin-associated periodic syndrome: a series of 136 patients from the Eurofever Registry.Monogenic autoinflammatory diseases: new insights into clinical aspects and pathogenesis.Advances in the understanding of familial Mediterranean fever and possibilities for targeted therapy.Blocking interleukin-1 in rheumatic diseases Interleukin-1 and acute brain injury.Interleukin-1 as a common denominator from autoinflammatory to autoimmune disorders: premises, perils, and perspectives Immunological loss-of-function due to genetic gain-of-function in humans: autosomal dominance of the third kind Rilonacept in the management of cryopyrin-associated periodic syndromes (CAPS).Autoinflammation: translating mechanism to therapy.Therapy of autoinflammatory syndromes.Sustained response and prevention of damage progression in patients with neonatal-onset multisystem inflammatory disease treated with anakinra: a cohort study to determine three- and five-year outcomes Prolonged urticaria and fever in a toddler.Inflammasome-mediated autoinflammatory disorders.Autoinflammatory Skin Disorders: The Inflammasomme in Focus.Biological treatments: new weapons in the management of monogenic autoinflammatory disorders Infectious complications associated with monoclonal antibodies and related small molecules Monogenic autoinflammatory diseases: concept and clinical manifestations.Developments in the scientific and clinical understanding of autoinflammatory disorders The spectrum of monogenic autoinflammatory syndromes: understanding disease mechanisms and use of targeted therapies.Role of interleukin-1beta during pain and inflammation.Monogenic autoinflammatory diseases: disorders of amplified danger sensing and cytokine dysregulation.Systemic JIA: new developments in the understanding of the pathophysiology and therapy.Treating inflammation by blocking interleukin-1 in humans.The emerging role of interleukin-1β in autoinflammatory diseases.Cryopyrin-associated periodic syndrome: an update on diagnosis and treatment response.Current status of understanding the pathogenesis and management of patients with NOMID/CINCA.Managing your patient with gout: a review of treatment options.The emerging role of interleukin-1β in autoinflammatory diseases.

P2860

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P2860

A pilot study to evaluate the safety and efficacy of the long-acting interleukin-1 inhibitor rilonacept (interleukin-1 Trap) in patients with familial cold autoinflammatory syndrome.

http://www.wikidata.org/entity/Q33871994

description

2008 nî lūn-bûn

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2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի օգոստոսին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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A pilot study to evaluate the ...... old autoinflammatory syndrome.

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Arthritis & Rheumatology

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A pilot study to evaluate the ...... old autoinflammatory syndrome.

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P2093

Beverly Barham

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Christopher Snyder

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Daniel L Kastner

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Frank Pucino

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Joanne H Papadopoulos

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Mildred Wilson

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Raphaela Goldbach-Mansky

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Robert A Wesley

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Sara Plehn

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Scott J Mellis

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P2860

Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome

Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases

Cryopyrin activates the inflammasome in response to toxins and ATP

Structural, expression, and evolutionary analysis of mouse CIAS1

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

A candidate gene for familial Mediterranean fever.

Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition.

P304

2432-2442

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10.1002/ART.23620

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8

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58

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23138946

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18668591

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