about
Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesMolecular features of the copper binding sites in the octarepeat domain of the prion proteinCoordination features and affinity of the Cu²+ site in the α-synuclein protein of Parkinson's diseaseZinc metallothionein imported into liver mitochondria modulates respirationMetals and amyloid-beta in Alzheimer's diseaseStructures of the G85R variant of SOD1 in familial amyotrophic lateral sclerosisStabilization of neurotoxic soluble beta-sheet-rich conformations of the Alzheimer's disease amyloid-beta peptideDivalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neuronsPhysical interaction and functional coupling between ACDP4 and the intracellular ion chaperone COX11, an implication of the role of ACDP4 in essential metal ion transport and homeostasisPossible involvement of copper(II) in Alzheimer disease.Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasisThe evolutionarily conserved trimeric structure of CutA1 proteins suggests a role in signal transductionStructure of putative CutA1 fromHomo sapiensdetermined at 2.05 Å resolutionStructural and Biophysical Properties of the Pathogenic SOD1 Variant H46R/H48Q †The structures of the CutA1 proteins fromThermus thermophilusandPyrococcus horikoshii: characterization of metal-binding sites and metal-induced assemblyA cadmium-transporting P1B-type ATPase in yeast Saccharomyces cerevisiae.The prokaryotic zinc-finger: structure, function and comparison with the eukaryotic counterpartThe neuronal adaptor protein X11alpha interacts with the copper chaperone for SOD1 and regulates SOD1 activityMechanisms of divalent metal toxicity in affective disordersIron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseasesMagnetic nanoparticles for theragnosticsRole of the Menkes copper-transporting ATPase in NMDA receptor-mediated neuronal toxicityAn engineered palette of metal ion quenchable fluorescent proteinsIn situ imaging of metals in cells and tissuesCellular and biochemical actions of melatonin which protect against free radicals: role in neurodegenerative disordersA model of posttraumatic epilepsy after penetrating brain injuries: effect of lesion size and metal fragments.S-nitrosothiol depletion in amyotrophic lateral sclerosis.Highly selective and sensitive fluorescence detection of Zn(2+) and Cd(2+) ions by using an acridine sensor.Mapping Cu(II) binding sites in prion proteins by diethyl pyrocarbonate modification and matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometric footprinting.Anomalous venous blood flow and iron deposition in multiple sclerosis.Two-photon imaging of Zn2+ dynamics in mossy fiber boutons of adult hippocampal slices.Increased expression and local accumulation of the prion protein, Alzheimer Aβ peptides, superoxide dismutase 1, and nitric oxide synthases 1 & 2 in muscle in a rabbit model of diabetes.In vivo reduction of amyloid-beta by a mutant copper transporterThe Case for Abandoning Therapeutic Chelation of Copper Ions in Alzheimer's DiseaseZinc overload enhances APP cleavage and Aβ deposition in the Alzheimer mouse brainStructure and dissociation characteristics of metal chloride anion clusters containing redox-active metal ions studied by laser desorption and electrospray ionization mass spectrometry and ab initio calculations.Fluorescence Sensing of Zinc and Mercury Ions with Hydrophilic 1,2,3-Triazolyl Fluorene Probes.Structural characterization of copper(II) binding to alpha-synuclein: Insights into the bioinorganic chemistry of Parkinson's disease.Zn(II)-coordination modulated ligand photophysical processes - the development of fluorescent indicators for imaging biological Zn(II) ionsThe galvanization of beta-amyloid in Alzheimer's disease.
P2860
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P2860
description
2000 nî lūn-bûn
@nan
2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Metals and neuroscience.
@ast
Metals and neuroscience.
@en
type
label
Metals and neuroscience.
@ast
Metals and neuroscience.
@en
prefLabel
Metals and neuroscience.
@ast
Metals and neuroscience.
@en
P1476
Metals and neuroscience
@en
P2093
P304
P356
10.1016/S1367-5931(99)00073-3
P577
2000-04-01T00:00:00Z