Transcription inhibition by platinum-DNA cross-links in live mammalian cells.
about
Phenanthriplatin, a monofunctional DNA-binding platinum anticancer drug candidate with unusual potency and cellular activity profileMitochondrial DNA damage and its consequences for mitochondrial gene expressionReview of Cisplatin and oxaliplatin in current immunogenic and monoclonal antibody treatmentsReversible p53 inhibition prevents cisplatin ototoxicity without blocking chemotherapeutic efficacyBinding of kinetically inert metal ions to RNA: the case of platinum(II).FAB, ESI and MALDI Mass Spectrometric methods in the study of metallo-drugs and their biomolecular interactions.Repair of cisplatin-induced DNA interstrand crosslinks by a replication-independent pathway involving transcription-coupled repair and translesion synthesisUnderstanding and improving platinum anticancer drugs--phenanthriplatinPhosphorylation of p68 RNA helicase by p38 MAP kinase contributes to colon cancer cells apoptosis induced by oxaliplatin.Ototoxic Model of Oxaliplatin and Protection from Nicotinamide Adenine DinucleotideRole of endonucleases XPF and XPG in nucleotide excision repair of platinated DNA and cisplatin/oxaliplatin cytotoxicity.Monofunctional platinum-DNA adducts are strong inhibitors of transcription and substrates for nucleotide excision repair in live mammalian cellsEffects of 6-thioguanine and S6-methylthioguanine on transcription in vitro and in human cells.Visualizing inhibition of nucleosome mobility and transcription by cisplatin-DNA interstrand crosslinks in live mammalian cellsModification of platinum sensitivity by KEAP1/NRF2 signals in non-small cell lung cancer.Synthetic methods for the preparation of platinum anticancer complexes.Inhibiting eukaryotic transcription: Which compound to choose? How to evaluate its activity?Notch3-specific inhibition using siRNA knockdown or GSI sensitizes paclitaxel-resistant ovarian cancer cells.Anticancer activity of hydrogen-bond-stabilized half-sandwich Ru(II) complexes with heterocycles.Ruthenium dihydroxybipyridine complexes are tumor activated prodrugs due to low pH and blue light induced ligand releaseRole of platinum DNA damage-induced transcriptional inhibition in chemotherapy-induced neuronal atrophy and peripheral neurotoxicity.Substitution-inert trinuclear platinum complexes efficiently condense/aggregate nucleic acids and inhibit enzymatic activity.Review of Cisplatin and Oxaliplatin in Current Immunogenic and Monoclonal Antibodies Perspective.Metal to ligand charge transfer induced DNA photobinding in a Ru(II)-Pt(II) supramolecule using red light in the therapeutic window: a new mechanism for DNA modification.A light-activated metal complex targets both DNA and RNA in a fluorescent in vitro transcription and translation assay.Photochemistry and DNA photocleavage by a new unsupported dirhodium(II,II) complex.Comparative study on the induction of complex genomic alterations after exposure of mammalian cells to carboplatin and oxaliplatin.Chemoresistant lung cancer stem cells display high DNA repair capability to remove cisplatin-induced DNA damage.Chemotherapeutic-Induced Cardiovascular Dysfunction: Physiological Effects, Early Detection-The Role of Telomerase to Counteract Mitochondrial Defects and Oxidative Stress.Base and nucleotide excision repair facilitate resolution of platinum drugs-induced transcription blockage
P2860
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P2860
Transcription inhibition by platinum-DNA cross-links in live mammalian cells.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Transcription inhibition by platinum-DNA cross-links in live mammalian cells.
@ast
Transcription inhibition by platinum-DNA cross-links in live mammalian cells.
@en
type
label
Transcription inhibition by platinum-DNA cross-links in live mammalian cells.
@ast
Transcription inhibition by platinum-DNA cross-links in live mammalian cells.
@en
prefLabel
Transcription inhibition by platinum-DNA cross-links in live mammalian cells.
@ast
Transcription inhibition by platinum-DNA cross-links in live mammalian cells.
@en
P2860
P356
P1476
Transcription inhibition by platinum-DNA cross-links in live mammalian cells.
@en
P2093
MyatNoeZin Myint
Wee Han Ang
P2860
P304
P356
10.1021/JA101495V
P407
P577
2010-06-01T00:00:00Z