Inactivation of gilGT, encoding a C-glycosyltransferase, and gilOIII, encoding a P450 enzyme, allows the details of the late biosynthetic pathway to gilvocarcin V to be delineated.
about
Enzymatic methods for glyco(diversification/randomization) of drugs and small moleculesNatural-product sugar biosynthesis and enzymatic glycodiversification.Cloning and characterization of the ravidomycin and chrysomycin biosynthetic gene clustersGilR, an unusual lactone-forming enzyme involved in gilvocarcin biosynthesis.Engineered biosynthesis of gilvocarcin analogues with altered deoxyhexopyranose moieties.Enzymatic methylation and structure-activity-relationship studies on polycarcin V, a gilvocarcin-type antitumor agent.Enzymatic total synthesis of defucogilvocarcin M and its implications for gilvocarcin biosynthesis.Inactivation of the ketoreductase gilU gene of the gilvocarcin biosynthetic gene cluster yields new analogues with partly improved biological activity.Angucyclines: Biosynthesis, mode-of-action, new natural products, and synthesis.Delineation of gilvocarcin, jadomycin, and landomycin pathways through combinatorial biosynthetic enzymology.Cytochromes P450 for natural product biosynthesis in Streptomyces: sequence, structure, and function.Multi-oxygenase complexes of the gilvocarcin and jadomycin biosyntheses.Roles of the synergistic reductive O-methyltransferase GilM and of O-methyltransferase GilMT in the gilvocarcin biosynthetic pathway.OleD Loki as a Catalyst for Tertiary Amine and Hydroxamate Glycosylation.
P2860
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P2860
Inactivation of gilGT, encoding a C-glycosyltransferase, and gilOIII, encoding a P450 enzyme, allows the details of the late biosynthetic pathway to gilvocarcin V to be delineated.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Inactivation of gilGT, encodin ...... ilvocarcin V to be delineated.
@ast
Inactivation of gilGT, encodin ...... ilvocarcin V to be delineated.
@en
type
label
Inactivation of gilGT, encodin ...... ilvocarcin V to be delineated.
@ast
Inactivation of gilGT, encodin ...... ilvocarcin V to be delineated.
@en
prefLabel
Inactivation of gilGT, encodin ...... ilvocarcin V to be delineated.
@ast
Inactivation of gilGT, encodin ...... ilvocarcin V to be delineated.
@en
P2093
P2860
P356
P1433
P1476
Inactivation of gilGT, encodin ...... ilvocarcin V to be delineated.
@en
P2093
Andrew McCormick
Carsten Fischer
Jürgen Rohr
Madan Kumar Kharel
P2860
P304
P356
10.1002/CBIC.200600031
P577
2006-07-01T00:00:00Z