Structural basis for the specificity of the initiation of HIV-1 reverse transcription.
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Identification of critical elements in the tRNA acceptor stem and T(Psi)C loop necessary for human immunodeficiency virus type 1 infectivityStructural determinants and mechanism of HIV-1 genome packagingStructural polymorphism of the HIV-1 leader region explored by computational methods.The crystal structure of HIV reverse-transcription primer tRNA(Lys,3) shows a canonical anticodon loopInitiation of HIV-1 reverse transcription is regulated by a primer activation signalIn vitro evidence for a long range pseudoknot in the 5'-untranslated and matrix coding regions of HIV-1 genomic RNADirect and indirect contributions of RNA secondary structure elements to the initiation of HIV-1 reverse transcriptionInhibition of both HIV-1 reverse transcription and gene expression by a cyclic peptide that binds the Tat-transactivating response element (TAR) RNAStructures of complexes formed by HIV-1 reverse transcriptase at a termination site of DNA synthesis.Identification of specific HIV-1 reverse transcriptase contacts to the viral RNA:tRNA complex by mass spectrometry and a primary amine selective reagentA genomic selection strategy to identify accessible and dimerization blocking targets in the 5'-UTR of HIV-1 RNAChanges in Rous sarcoma virus RNA secondary structure near the primer binding site upon tRNATrp primer annealing.Mutations in the RNase H domain of HIV-1 reverse transcriptase affect the initiation of DNA synthesis and the specificity of RNase H cleavage in vivo.Structure of the RNA inside the vesicular stomatitis virus nucleocapsidNMR and biochemical characterization of recombinant human tRNA(Lys)3 expressed in Escherichia coli: identification of posttranscriptional nucleotide modifications required for efficient initiation of HIV-1 reverse transcription.Structural and functional properties of the HIV-1 RNA-tRNA(Lys)3 primer complex annealed by the nucleocapsid protein: comparison with the heat-annealed complexCoordinate roles of Gag and RNA helicase A in promoting the annealing of formula to HIV-1 RNAInitiation complex dynamics direct the transitions between distinct phases of early HIV reverse transcription.The Interaction between tRNA(Lys) 3 and the primer activation signal deciphered by NMR spectroscopy.Role of HIV-1 nucleocapsid protein in HIV-1 reverse transcription.The tRNA primer activation signal in the human immunodeficiency virus type 1 genome is important for initiation and processive elongation of reverse transcriptionReverse Transcriptase and Cellular Factors: Regulators of HIV-1 Reverse Transcription.Requirements for efficient minus strand strong-stop DNA transfer in human immunodeficiency virus 1.Molecular mechanisms by which human immunodeficiency virus type 1 integrase stimulates the early steps of reverse transcription.High-throughput SHAPE analysis reveals structures in HIV-1 genomic RNA strongly conserved across distinct biological statesHeterogeneous structures formed by conserved RNA sequences within the HIV reverse transcription initiation site.Synthetic tRNALys,3 as the replication primer for the HIV-1HXB2 and HIV-1Mal genomes.Small-angle X-ray scattering-derived structure of the HIV-1 5' UTR reveals 3D tRNA mimicry.Reverse Transcription in the Saccharomyces cerevisiae Long-Terminal Repeat Retrotransposon Ty3.Destabilization of tRNA3(Lys) from the primer-binding site of HIV-1 genome by anti-A loop polyamide nucleotide analogHuman immunodeficiency virus type-1 reverse transcription can be inhibited in vitro by oligonucleotides that target both natural and synthetic tRNA primers.A structured RNA motif is involved in correct placement of the tRNA(3)(Lys) primer onto the human immunodeficiency virus genome.MD simulations of HIV-1 RT primer-template complex: effect of modified nucleosides and antisense PNA oligomer.The annealing mechanism of HIV-1 reverse transcription primer onto the viral genome.On the importance of the primer activation signal for initiation of tRNA(lys3)-primed reverse transcription of the HIV-1 RNA genome.Does the HIV-1 primer activation signal interact with tRNA3(Lys) during the initiation of reverse transcription?Efficient initiation of HIV-1 reverse transcription in vitro. Requirement for RNA sequences downstream of the primer binding site abrogated by nucleocapsid protein-dependent primer-template interactions.Initiation of HIV Reverse TranscriptionBinding of the eukaryotic translation elongation factor 1A with the 5'UTR of HIV-1 genomic RNA is important for reverse transcription.In vitro evidence for the interaction of tRNA(3)(Lys) with U3 during the first strand transfer of HIV-1 reverse transcription.
P2860
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P2860
Structural basis for the specificity of the initiation of HIV-1 reverse transcription.
description
1999 nî lūn-bûn
@nan
1999 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Structural basis for the specificity of the initiation of HIV-1 reverse transcription.
@ast
Structural basis for the specificity of the initiation of HIV-1 reverse transcription.
@en
type
label
Structural basis for the specificity of the initiation of HIV-1 reverse transcription.
@ast
Structural basis for the specificity of the initiation of HIV-1 reverse transcription.
@en
prefLabel
Structural basis for the specificity of the initiation of HIV-1 reverse transcription.
@ast
Structural basis for the specificity of the initiation of HIV-1 reverse transcription.
@en
P2093
P2860
P356
P1433
P1476
Structural basis for the specificity of the initiation of HIV-1 reverse transcription.
@en
P2093
B Ehresmann
C Ehresmann
S F Le Grice
P2860
P304
P356
10.1093/EMBOJ/18.4.1038
P407
P577
1999-02-01T00:00:00Z