Concentration-effect relationships for the drug of abuse gamma-hydroxybutyric acid
about
γ-Hydroxybutyric acid (GHB) is not an agonist of extrasynaptic GABAA receptorsMechanistic modeling of monocarboxylate transporter-mediated toxicokinetic/toxicodynamic interactions between γ-hydroxybutyrate and L-lactate.Mechanistic toxicokinetic model for gamma-hydroxybutyric acid: inhibition of active renal reabsorption as a potential therapeutic strategy.Effect of 3,4-methylenedioxymethamphetamine on the toxicokinetics and sedative effects of the drug of abuse, γ-hydroxybutyric acid.Use of a local sensitivity analysis to inform study design based on a mechanistic toxicokinetic model for γ-hydroxybutyric acid.A Novel Monocarboxylate Transporter Inhibitor as a Potential Treatment Strategy for γ-Hydroxybutyric Acid Overdose.Brain uptake of the drug of abuse γ-hydroxybutyric acid in rats.γ-Hydroxybutyrate blood/plasma partitioning: effect of physiologic pH on transport by monocarboxylate transporters.γ-Hydroxybutyrate (GHB)-induced respiratory depression: combined receptor-transporter inhibition therapy for treatment in GHB overdose.Brain extracellular γ-hydroxybutyrate concentrations are decreased by L-lactate in rats: role in the treatment of overdosesToxicokinetics/Toxicodynamics of γ-hydroxybutyrate-ethanol intoxication: evaluation of potential treatment strategies.Monocarboxylate Transporter Inhibition with Osmotic Diuresis Increases γ-Hydroxybutyrate Renal Elimination in Humans: A Proof-of-Concept Study.A critical evaluation of the gamma-hydroxybutyrate (GHB) model of absence seizures.Mechanisms for the Specific Properties of γ-Hydroxybutyrate in Brain.Pharmacological Treatment in γ-Hydroxybutyrate (GHB) and γ-Butyrolactone (GBL) Dependence: Detoxification and Relapse Prevention.Baclofen in gamma-hydroxybutyrate withdrawal: patterns of use and online availability.
P2860
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P2860
Concentration-effect relationships for the drug of abuse gamma-hydroxybutyric acid
description
2010 nî lūn-bûn
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2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Concentration-effect relationships for the drug of abuse gamma-hydroxybutyric acid
@ast
Concentration-effect relationships for the drug of abuse gamma-hydroxybutyric acid
@en
type
label
Concentration-effect relationships for the drug of abuse gamma-hydroxybutyric acid
@ast
Concentration-effect relationships for the drug of abuse gamma-hydroxybutyric acid
@en
prefLabel
Concentration-effect relationships for the drug of abuse gamma-hydroxybutyric acid
@ast
Concentration-effect relationships for the drug of abuse gamma-hydroxybutyric acid
@en
P2093
P2860
P356
P1476
Concentration-effect relationships for the drug of abuse gamma-hydroxybutyric acid
@en
P2093
Bridget L Morse
Marilyn E Morris
Melanie A Felmlee
Samuel A Roiko
P2860
P304
P356
10.1124/JPET.109.165381
P407
P577
2010-03-09T00:00:00Z