The C-terminus of the kinase-defective neuregulin receptor ErbB-3 confers mitogenic superiority and dictates endocytic routing.
about
Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3Neuregulin signaling on glucose transport in muscle cellsClathrin-independent endocytosis of ErbB2 in geldanamycin-treated human breast cancer cells.c-Src modulates ErbB2 and ErbB3 heterocomplex formation and function.Treatment of vestibular schwannoma cells with ErbB inhibitorsBeyond the RING: CBL proteins as multivalent adapters.The E3 ubiquitin ligase NEDD4 negatively regulates HER3/ErbB3 level and signaling.Activation of EGFR, HER2 and HER3 by neurotensin/neurotensin receptor 1 renders breast tumors aggressive yet highly responsive to lapatinib and metformin in mice.Therapeutic strategies and mechanisms of tumorigenesis of HER2-overexpressing breast cancerEndocytosis and intracellular trafficking of ErbBs.Dimerization, ubiquitylation and endocytosis go together in growth hormone receptor function.c-erbB-3: a nuclear protein in mammary epithelial cells.Epidermal growth factor and membrane trafficking. EGF receptor activation of endocytosis requires Rab5aEGFRvIII undergoes activation-dependent downregulation mediated by the Cbl proteins.VEGF signaling inhibitors: more pro-apoptotic than anti-angiogenic.Endocytic downregulation of ErbB receptors: mechanisms and relevance in cancerThe ERBB3 receptor in cancer and cancer gene therapyThe kinase-null EphB6 receptor undergoes transphosphorylation in a complex with EphB1.Monoclonal antibody-induced ErbB3 receptor internalization and degradation inhibits growth and migration of human melanoma cells.Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways leading to cell survival.Stimulation of cell proliferation by endosomal epidermal growth factor receptor as revealed through two distinct phases of signaling.Cbl-b interacts with ubiquitinated proteins; differential functions of the UBA domains of c-Cbl and Cbl-b.Effect of estradiol on estrogen receptor-alpha gene expression and activity can be modulated by the ErbB2/PI 3-K/Akt pathway.Internalization of inactive EGF receptor into endosomes and the subsequent activation of endosome-associated EGF receptors. Epidermal growth factor.c-Cbl is a suppressor of the neu oncogene.Effects of oncogenic ErbB2 on G1 cell cycle regulators in breast tumour cells.Where EGF receptors transmit their signals.Emerging functions of the EGFR in cancer.
P2860
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P2860
The C-terminus of the kinase-defective neuregulin receptor ErbB-3 confers mitogenic superiority and dictates endocytic routing.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The C-terminus of the kinase-d ...... nd dictates endocytic routing.
@ast
The C-terminus of the kinase-d ...... nd dictates endocytic routing.
@en
type
label
The C-terminus of the kinase-d ...... nd dictates endocytic routing.
@ast
The C-terminus of the kinase-d ...... nd dictates endocytic routing.
@en
prefLabel
The C-terminus of the kinase-d ...... nd dictates endocytic routing.
@ast
The C-terminus of the kinase-d ...... nd dictates endocytic routing.
@en
P2093
P2860
P356
P1433
P1476
The C-terminus of the kinase-d ...... nd dictates endocytic routing.
@en
P2093
P2860
P304
P356
10.1093/EMBOJ/18.12.3348
P407
P577
1999-06-01T00:00:00Z