Sirtuin 1 enzymatic activity is required for cartilage homeostasis in vivo in a mouse model
about
Cellular ageing mechanisms in osteoarthritisInflammation and intracellular metabolism: new targets in OAEpigenetic Regulation of Chondrocyte Catabolism and Anabolism in OsteoarthritisEmerging regulators of the inflammatory process in osteoarthritisReview: Metabolic Regulation of Inflammation in OsteoarthritisDOT1L safeguards cartilage homeostasis and protects against osteoarthritis.Sirtuin-1 (SIRT1) is required for promoting chondrogenic differentiation of mesenchymal stem cells.Dysregulated serum IL-23 and SIRT1 activity in peripheral blood mononuclear cells of patients with rheumatoid arthritis.Emerging targets in osteoarthritis therapy.Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to ApoptosisHistone Deacetylases in Bone Development and Skeletal Disorders.Acetylation reduces SOX9 nuclear entry and ACAN gene transactivation in human chondrocytes.SIRT1 is a Highly Networked Protein That Mediates the Adaptation to Chronic Physiological Stress.Paracrine effects of human adipose-derived mesenchymal stem cells in inflammatory stress-induced senescence features of osteoarthritic chondrocytesAgeing and osteoarthritis: a circadian rhythm connection.Low Shear Stress Attenuates COX-2 Expression Induced by Resistin in Human Osteoarthritic Chondrocytes.The brain-joint axis in osteoarthritis: nerves, circadian clocks and beyond.The Role of Sirtuins in Cartilage Homeostasis and Osteoarthritis.Histone Deacetylases in Cartilage Homeostasis and Osteoarthritis.The Potential of Circadian Realignment in Rheumatoid Arthritis.Culture expansion in low-glucose conditions preserves chondrocyte differentiation and enhances their subsequent capacity to form cartilage tissue in three-dimensional culture.Clock Gene Bmal1 Modulates Human Cartilage Gene Expression by Crosstalk With Sirt1.Resveratrol and N-acetylcysteine influence redox balance in equine articular chondrocytes under acidic and very low oxygen conditions.Resveratrol, a sirtuin 1 activator, increases IL-6 production by peripheral blood mononuclear cells of patients with knee osteoarthritis.Resveratrol downregulates inflammatory pathway activated by lymphotoxin α (TNF-β) in articular chondrocytes: Comparison with TNF-α.Therapeutic Effects of Olive and Its Derivatives on Osteoarthritis: From Bench to Bedside.Disruption of Sirt1 in chondrocytes causes accelerated progression of osteoarthritis under mechanical stress and during ageing in mice.Emerging Players at the Intersection of Chondrocyte Loss of Maturational Arrest, Oxidative Stress, Senescence and Low-Grade Inflammation in Osteoarthritis.Sirtuin-1(SIRT1) stimulates growth plate chondrogenesis by attenuating the PERK-eIF-2α-CHOP pathway in the unfolded protein response.Epigenetics in osteoarthritis: Potential of HDAC inhibitors as therapeutics.Intraperitoneal injection of the SIRT1 activator SRT1720 attenuates the progression of experimental osteoarthritis in mice.
P2860
Q26746549-886CB067-6F92-438A-B27A-A7FC0476CE96Q26777620-4489E4EB-E9B5-4785-BA88-357D44E7E53DQ26799110-84E3D7AC-DCD1-42DF-ACD0-7212F12BEA9AQ26829840-F64039C4-1BA6-4969-9975-06BA67C99591Q28079875-1B13F0F0-F502-45A6-91A7-5AFDBAE99917Q33827165-980E536E-3B96-480F-B73B-DBD63900889CQ34070378-FCE0CC66-7D27-4E9C-9786-D9A40200E2B7Q35208102-F1DB1D89-8DF1-4412-9647-7CD83ADAFB70Q35752078-6C6EE404-1DCD-46AF-BE36-524F7BA51964Q36098910-0F4AD4AA-9445-41B4-ADD2-F418AE9E0A80Q36146330-5FF50318-345B-46ED-9036-065648BE8590Q36863764-0AE99928-6CD7-4F86-8EFA-928E648BF10DQ37150520-F0D0FF3B-B735-4132-B0D5-EC5A02AAB99DQ37274985-4A2B9902-A698-486D-A5B4-A1D9C6063F22Q38235496-1C5DDFF2-1778-4338-B2CE-A45563AEAFC2Q38741594-0E8CFF62-A280-4D16-BCAB-7BE94CDDED22Q38852796-62BE85A6-6E34-4772-B048-7C7D4009D026Q38854590-10576ED8-94A3-4C21-849E-FCABB2DAA9CCQ38893201-3F228FD5-98E5-4F26-8615-E980912E2DF1Q39366944-9A10581D-5510-4857-B6AB-FE7482E5127FQ41966084-17D349A4-87BB-4278-9B96-1B4D8DAAAD51Q42392472-88BFD43F-6763-43E7-BD6C-C34A5ADDA65EQ42582139-87FE371A-A1CE-4395-B6F2-0817D3902DDFQ43084482-DD9BF320-580A-449C-9541-26EF7671B4F7Q46035301-744EEE70-0AE7-40CD-B0D7-FF86DDD601C0Q47101159-53D5D5EB-1974-4D2A-9979-B0021543C900Q50948674-E279DBDC-FE97-4E5F-8AAC-F88EC1F25FB3Q51758259-FF15EA6D-85AF-40D0-9659-176861F2C1D6Q52589289-B65408C4-461E-4924-9D98-6A97A6E37875Q53102213-A24188C0-C551-4318-8CE6-E6F43656D576Q55480930-B466288A-AC03-4A30-AF17-4F3EEDB17898
P2860
Sirtuin 1 enzymatic activity is required for cartilage homeostasis in vivo in a mouse model
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Sirtuin 1 enzymatic activity i ...... tasis in vivo in a mouse model
@ast
Sirtuin 1 enzymatic activity i ...... tasis in vivo in a mouse model
@en
type
label
Sirtuin 1 enzymatic activity i ...... tasis in vivo in a mouse model
@ast
Sirtuin 1 enzymatic activity i ...... tasis in vivo in a mouse model
@en
prefLabel
Sirtuin 1 enzymatic activity i ...... tasis in vivo in a mouse model
@ast
Sirtuin 1 enzymatic activity i ...... tasis in vivo in a mouse model
@en
P2093
P2860
P356
P1476
Sirtuin 1 enzymatic activity i ...... tasis in vivo in a mouse model
@en
P2093
Kristien J Zaal
Michael W McBurney
Odile Gabay
Viktoria Gagarina
Xiao Hong He
Yingjie Song
P2860
P304
P356
10.1002/ART.37750
P577
2013-01-01T00:00:00Z