Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal. - Wikidata - wikimedia - TriplyDB

Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal.

Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal.

http://www.wikidata.org/entity/Q33894555

about

MicroRNAs: regulators of neuronal fate Adult neurogenesis in the mammalian brain: significant answers and significant questions Signaling mechanisms regulating adult neural stem cells and neurogenesis Molecular Mechanism of Adult Neurogenesis and its Association with Human Brain Diseases Insights into the Biology and Therapeutic Applications of Neural Stem Cells Common stemness regulators of embryonic and cancer stem cells Functional circuits of new neurons in the dentate gyrus microRNAs: key triggers of neuronal cell fate TLX: A master regulator for neural stem cell maintenance and neurogenesis Wnt signaling in neuropsychiatric disorders: ties with adult hippocampal neurogenesis and behavior Wnt your brain be inflamed? Yes, it Wnt!Integrin signalling regulates the expansion of neuroepithelial progenitors and neurogenesis via Wnt7a and Decorin.The protective effect of melatonin on neural stem cell against LPS-induced inflammation A novel function of the proneural factor Ascl1 in progenitor proliferation identified by genome-wide characterization of its targets The human orphan nuclear receptor tailless (TLX, NR2E1) is druggable Unlocking mechanisms in interleukin-1β-induced changes in hippocampal neurogenesis--a role for GSK-3β and TLX Genome-wide loss of 5-hmC is a novel epigenetic feature of Huntington's disease A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties.Leptin restores adult hippocampal neurogenesis in a chronic unpredictable stress model of depression and reverses glucocorticoid-induced inhibition of GSK-3β/β-catenin signaling Invasive Cell Fate Requires G1 Cell-Cycle Arrest and Histone Deacetylase-Mediated Changes in Gene Expression A multi-resource data integration approach: identification of candidate genes regulating cell proliferation during neocortical development.Phosphatase WIP1 regulates adult neurogenesis and WNT signaling during aging Nuclear receptor TLX stimulates hippocampal neurogenesis and enhances learning and memory in a transgenic mouse model Wnt signaling pathway protein LEF1 in cancer, as a biomarker for prognosis and a target for treatment.Molecular targets of chromatin repressive mark H3K9me3 in primate progenitor cells within adult neurogenic niches.A transcriptional mechanism integrating inputs from extracellular signals to activate hippocampal stem cells.Platelet-derived growth factor-BB restores HIV Tat -mediated impairment of neurogenesis: role of GSK-3β/β-catenin.Genes and signaling networks regulated during zebrafish optic vesicle morphogenesis Characterization of induced neural progenitors from skin fibroblasts by a novel combination of defined factors.Nuclear receptors in stem cells and their therapeutic potential Characterization of TLX expression in neural stem cells and progenitor cells in adult brains.The molecular profiles of neural stem cell niche in the adult subventricular zone.TLX activates MMP-2, promotes self-renewal of tumor spheres in neuroblastoma and correlates with poor patient survival.Neurogenesis in the embryonic and adult brain: same regulators, different roles LGR5 promotes the proliferation and tumor formation of cervical cancer cells through the Wnt/β-catenin signaling pathway.REST and CoREST are transcriptional and epigenetic regulators of seminal neural fate decisions.Wnt signaling and the control of human stem cell fate.Neuronal differentiation distinguishes supratentorial and infratentorial childhood ependymomas Akt increases sox2 expression in adult hippocampal neural progenitor cells, but increased sox2 does not promote proliferation.Cdo suppresses canonical Wnt signalling via interaction with Lrp6 thereby promoting neuronal differentiation.

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Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal.

http://www.wikidata.org/entity/Q33894555

description

2009 nî lūn-bûn

@nan

2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Orphan nuclear receptor TLX ac ...... roliferation and self-renewal.

@ast

Orphan nuclear receptor TLX ac ...... roliferation and self-renewal.

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type

label

Orphan nuclear receptor TLX ac ...... roliferation and self-renewal.

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Orphan nuclear receptor TLX ac ...... roliferation and self-renewal.

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prefLabel

Orphan nuclear receptor TLX ac ...... roliferation and self-renewal.

@ast

Orphan nuclear receptor TLX ac ...... roliferation and self-renewal.

@en

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P1433

Nature Cell Biology

P1476

Orphan nuclear receptor TLX ac ...... roliferation and self-renewal.

@en

P2093

Chunnian Zhao

http://www.w3.org/2001/XMLSchema#string

Fred H Gage

http://www.w3.org/2001/XMLSchema#string

Guoqiang Sun

http://www.w3.org/2001/XMLSchema#string

Peng Ye

http://www.w3.org/2001/XMLSchema#string

Qiuhao Qu

http://www.w3.org/2001/XMLSchema#string

Ruth T Yu

http://www.w3.org/2001/XMLSchema#string

Su Yang

http://www.w3.org/2001/XMLSchema#string

Wenwu Li

http://www.w3.org/2001/XMLSchema#string

Yanhong Shi

http://www.w3.org/2001/XMLSchema#string

P2860

Sexually dimorphic development of the mammalian reproductive tract requires Wnt-7a

A new secreted protein that binds to Wnt proteins and inhibits their activities

Wnt regulation of progenitor maturation in the cortex depends on Shh or fibroblast growth factor 2

Orphan nuclear receptor TLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferation

A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination

The nuclear receptor tailless is required for neurogenesis in the adult subventricular zone

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

Subventricular zone astrocytes are neural stem cells in the adult mammalian brain

FGF-2-responsive neural stem cell proliferation requires CCg, a novel autocrine/paracrine cofactor

The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation

P2888

P304

31-40; sup pp 1-9

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scholarly article

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10.1038/NCB2001

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P433

1

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P478

12

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P50

Ronald M. Evans

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2009-12-13T00:00:00Z

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40688312

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1045350043

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20010817

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2880892

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