Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors.
about
BRCA1 promoter methylation in peripheral blood DNA of mutation negative familial breast cancer patients with a BRCA1 tumour phenotypeDNA methylation profiling of ovarian carcinomas and their in vitro models identifies HOXA9, HOXB5, SCGB3A1, and CRABP1 as novel targetsMutator pathways unleashed by epigenetic silencing in human cancerEpimutation and cancer: a new carcinogenic mechanism of Lynch syndrome (Review)The TES gene at 7q31.1 is methylated in tumours and encodes a novel growth-suppressing LIM domain proteinHIN-1, a putative cytokine highly expressed in normal but not cancerous mammary epithelial cellsBRCAness: finding the Achilles heel in ovarian cancerHigh rates of loss of heterozygosity on chromosome 19p13 in human breast cancerMicroarray analysis of pediatric ependymoma identifies a cluster of 112 candidate genes including four transcripts at 22q12.1-q13.3The role of the breast cancer susceptibility gene 1 (BRCA1) in sporadic epithelial ovarian cancerMolecular tumor profiling: translating genomic insights into clinical advancesCharacteristic promoter hypermethylation signatures in male germ cell tumorsFrequent promoter methylation of CDH1, DAPK, RARB, and HIC1 genes in carcinoma of cervix uteri: its relationship to clinical outcomeThe p53 pathway in breast cancerOvarian Cancer: The Fallopian Tube as the Site of Origin and Opportunities for PreventionEpigenetic mechanisms involved in melanoma pathogenesis and chemoresistanceHomologous Recombination Deficiency: Exploiting the Fundamental Vulnerability of Ovarian CancerInduced pluripotent stem cell technology for dissecting the cancer epigenomeOncogenes induce the cancer-associated fibroblast phenotype: metabolic symbiosis and "fibroblast addiction" are new therapeutic targets for drug discoveryBeyond Breast and Ovarian Cancers: PARP Inhibitors for BRCA Mutation-Associated and BRCA-Like Solid TumorsBRCA1, a 'complex' protein involved in the maintenance of genomic stabilityEpigenetics in breast cancer: what's new?Genomic scars as biomarkers of homologous recombination deficiency and drug response in breast and ovarian cancersBreast cancer epigenetics: from DNA methylation to microRNAsIntegrated genomic analyses of ovarian carcinomaUse of poly ADP-ribose polymerase [PARP] inhibitors in cancer cells bearing DDR defects: the rationale for their inclusion in the clinicPredictors and Modulators of Synthetic Lethality: An Update on PARP Inhibitors and Personalized MedicineEpigenetics in Cancer: A Hematological PerspectiveInactivation of the Fanconi anemia/BRCA pathway in lung and oral cancers: implications for treatment and survivalInactivation of p57KIP2 by regional promoter hypermethylation and histone deacetylation in human tumorsEpigenetic inactivation of the premature aging Werner syndrome gene in human cancerMultigene methylation analysis of gastrointestinal tumors: TPEF emerges as a frequent tumor-specific aberrantly methylated marker that can be detected in peripheral bloodLung cancer epigenetics: emerging biomarkersPromoter hypomethylation, especially around the E26 transformation-specific motif, and increased expression of poly (ADP-ribose) polymerase 1 in BRCA-mutated serous ovarian cancerAdenomatous polyposis coli (APC) gene promoter hypermethylation in primary breast cancersMethylation mattersDNA damage response genes and the development of cancer metastasisBRCA1 and Oxidative StressA genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignanciesConvergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis
P2860
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P2860
Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors.
description
2000 nî lūn-bûn
@nan
2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors.
@ast
Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors.
@en
type
label
Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors.
@ast
Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors.
@en
prefLabel
Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors.
@ast
Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors.
@en
P2093
P356
P1476
Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors.
@en
P2093
Bussaglia E
Dominguez G
Gabrielson E
Matias-Guiu X
P304
P356
10.1093/JNCI/92.7.564
P407
P577
2000-04-01T00:00:00Z