A recombinant vaccine expressed in the milk of transgenic mice protects Aotus monkeys from a lethal challenge with Plasmodium falciparum.
about
Optimized expression of Plasmodium falciparum erythrocyte membrane protein 1 domains in Escherichia coliProduction of full-length soluble Plasmodium falciparum RH5 protein vaccine using a Drosophila melanogaster Schneider 2 stable cell line systemThe globalization of traditional medicine in northern peru: from shamanism to molecules.Plasmodium falciparum merozoite surface protein 1 blocks the proinflammatory protein S100PMalaria modeling: In vitro stem cells vs in vivo modelsImmunogenicity of self-associated aggregates and chemically cross-linked conjugates of the 42 kDa Plasmodium falciparum merozoite surface protein-1Safety and reactogenicity of an MSP-1 malaria vaccine candidate: a randomized phase Ib dose-escalation trial in Kenyan children.Protection of rhesus monkeys by a DNA prime/poxvirus boost malaria vaccine depends on optimal DNA priming and inclusion of blood stage antigens.Phase 1 trial of malaria transmission blocking vaccine candidates Pfs25 and Pvs25 formulated with montanide ISA 51.Blood stage malaria vaccine eliciting high antigen-specific antibody concentrations confers no protection to young children in Western Kenya.The clinical-grade 42-kilodalton fragment of merozoite surface protein 1 of Plasmodium falciparum strain FVO expressed in Escherichia coli protects Aotus nancymai against challenge with homologous erythrocytic-stage parasites.posttranslational modification of recombinant Plasmodium falciparum apical membrane antigen 1: impact on functional immune responses to a malaria vaccine candidate.In vitro studies with recombinant Plasmodium falciparum apical membrane antigen 1 (AMA1): production and activity of an AMA1 vaccine and generation of a multiallelic responseVaccination of monkeys with recombinant Plasmodium falciparum apical membrane antigen 1 confers protection against blood-stage malariaNew candidate vaccines against blood-stage Plasmodium falciparum malaria: prime-boost immunization regimens incorporating human and simian adenoviral vectors and poxviral vectors expressing an optimized antigen based on merozoite surface protein 1Changes in antigen-specific cytokine and chemokine responses to Plasmodium falciparum antigens in a highland area of Kenya after a prolonged absence of malaria exposure.Biochemical and immunological characterization of bacterially expressed and refolded Plasmodium falciparum 42-kilodalton C-terminal merozoite surface protein 1.Immunity to recombinant plasmodium falciparum merozoite surface protein 1 (MSP1): protection in Aotus nancymai monkeys strongly correlates with anti-MSP1 antibody titer and in vitro parasite-inhibitory activity.CpG oligodeoxynucleotide and Montanide ISA 51 adjuvant combination enhanced the protective efficacy of a subunit malaria vaccinePlasmodium falciparum: immunization with MSP1-42 induced non-inhibitory antibodies that have no blocking activities but enhanced the potency of inhibitory anti-MSP1-42 antibodies.Evaluation of the Impact of Codon Optimization and N-Linked Glycosylation on Functional Immunogenicity of Pfs25 DNA Vaccines Delivered by In Vivo Electroporation in Preclinical Studies in MiceResults from tandem Phase 1 studies evaluating the safety, reactogenicity and immunogenicity of the vaccine candidate antigen Plasmodium falciparum FVO merozoite surface protein-1 (MSP1(42)) administered intramuscularly with adjuvant system AS01.IFNγ Responses to Pre-erythrocytic and Blood-stage Malaria Antigens Exhibit Differential Associations With Past Exposure and Subsequent Protection.Immunogenicity of bacterial-expressed recombinant Plasmodium knowlesi merozoite surface protein-142 (MSP-142).Cellular responses to modified Plasmodium falciparum MSP119 antigens in individuals previously exposed to natural malaria infection.Antibody responses to a novel Plasmodium falciparum merozoite surface protein vaccine correlate with protection against experimental malaria infection in Aotus monkeys.The fine specificity, but not the invasion inhibitory activity, of 19-kilodalton merozoite surface protein 1-specific antibodies is associated with resistance to malarial parasitemia in a cross-sectional survey in The Gambia.A novel malaria vaccine candidate antigen expressed in Tetrahymena thermophila.Erythropoiesis stimulating agents: approaches to modulate activity.Rice-produced MSP142 of Plasmodium falciparum elicits antibodies that inhibit parasite growth in vitro.Immunogenicity and malaria transmission reducing potency of Pfs48/45 and Pfs25 encoded by DNA vaccines administered by intramuscular electroporation.[Humoral immune anti-Plasmodium falciparum AMA1 and MSP1 response in two ethnic groups living in sympatry in Mali].
P2860
Q24802878-C3D5BB4D-8A84-4AF8-9B3B-0B1F98223D41Q26700012-2100D0D7-BBD7-4337-B640-5DDF741E8467Q26830049-50148297-908C-44EC-BE06-021552475962Q27972785-30921F48-BD12-44FF-A898-FCC326E6DCF2Q28071293-BEFB4470-9B8F-47EB-8779-21E0928CAAE2Q28484081-045F3A90-79E8-4A30-BC54-70765F922C9DQ33264521-F141E5B6-3F1B-4824-8B6C-51028DABFD37Q33303670-9FDE8B95-077A-48E0-9C64-9DB61697CDE4Q33350210-A9ECD356-AB8D-40CF-B2E0-8AB9F2AA2201Q33415066-11C15D3C-2AE4-454F-B2EA-124DFC6D0ADCQ33558061-BE7C1674-1FF6-4A38-8BE5-1528FEE64A0CQ33883252-C24B4F4D-9137-4901-B56A-C91685E66E7BQ34260615-587FB710-7F1B-4B5C-BF38-5D053E61D268Q34260722-A1A70549-4570-488F-B3D6-198FAB8D8EEBQ34290768-7585FD0F-F259-4837-B7BD-E190DFA9CE73Q34298486-4BD48200-7467-48C4-8B87-1717BDCBFA55Q34940333-9C416198-BE23-4C63-BF4B-BC081FBA4759Q34975629-A0572BDC-B3F6-43ED-8FAC-A9E76F6C24E9Q35550770-5AA995E7-CC80-4D39-B64D-37770FC49008Q35762375-122D6003-BE17-4AD3-A0C8-BC294C27291FQ35998776-F465A4FD-A99E-4862-97DB-CE3458E41FEAQ36639261-FBEA0FBF-95FB-4F75-9AE5-A872647EEDDFQ36812832-E9856465-6ADE-4EBB-9D9A-79789686EDD7Q37425845-CD7B6CCB-E162-4A4B-99D4-5885FE59FF9AQ37448753-A791B83E-5169-48FF-B19A-5E47DEA82439Q37452080-82E85BDD-0216-4752-A749-1E58C1B108A2Q37523653-A0DA68DF-6521-4EA0-BF94-5F2F2A80BB28Q37529646-E599204D-5030-4231-AA63-55986E2A3A34Q38121067-3E118CBB-741C-4AB6-B4EF-E22E0B9B8337Q38942086-9686834A-5F60-4C29-AEE3-8E60078A8B51Q38962773-AFBD211E-024D-4495-BCB9-2C44490FACE3Q46694488-9762F5FC-5743-48B7-A4AD-421374E0126D
P2860
A recombinant vaccine expressed in the milk of transgenic mice protects Aotus monkeys from a lethal challenge with Plasmodium falciparum.
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
A recombinant vaccine expresse ...... ge with Plasmodium falciparum.
@ast
A recombinant vaccine expresse ...... ge with Plasmodium falciparum.
@en
type
label
A recombinant vaccine expresse ...... ge with Plasmodium falciparum.
@ast
A recombinant vaccine expresse ...... ge with Plasmodium falciparum.
@en
prefLabel
A recombinant vaccine expresse ...... ge with Plasmodium falciparum.
@ast
A recombinant vaccine expresse ...... ge with Plasmodium falciparum.
@en
P2093
P2860
P356
P1476
A recombinant vaccine expresse ...... ge with Plasmodium falciparum.
@en
P2093
Allan Saul
Anthony W Stowers
David C Kaslow
Harry Meade
Lanling Zou
Li-how Chen Lh
Lynn Lambert
Michael C Kennedy
Timothy J Rice
Yanling Zhang
P2860
P304
P356
10.1073/PNAS.012590199
P407
P577
2001-12-18T00:00:00Z