Pituitary adenylate cyclase-activating polypeptide is a sympathoadrenal neurotransmitter involved in catecholamine regulation and glucohomeostasis - Wikidata - wikimedia - TriplyDB

Pituitary adenylate cyclase-activating polypeptide is a sympathoadrenal neurotransmitter involved in catecholamine regulation and glucohomeostasis

Pituitary adenylate cyclase-activating polypeptide is a sympathoadrenal neurotransmitter involved in catecholamine regulation and glucohomeostasis

http://www.wikidata.org/entity/Q33898110

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Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor Impact of PACAP and PAC1 receptor deficiency on the neurochemical and behavioral effects of acute and chronic restraint stress in male C57BL/6 mice.Comprehensive behavioral analysis of pituitary adenylate cyclase-activating polypeptide (PACAP) knockout mice.Meta-analysis of microarray-derived data from PACAP-deficient adrenal gland in vivo and PACAP-treated chromaffin cells identifies distinct classes of PACAP-regulated genes.The pituitary adenylate cyclase-activating polypeptide is a physiological inhibitor of platelet activation.Stress hormone synthesis in mouse hypothalamus and adrenal gland triggered by restraint is dependent on pituitary adenylate cyclase-activating polypeptide signaling.Reduced calcium current density in female versus male mouse adrenal chromaffin cells in situ.Temporally restricted role of retinal PACAP: integration of the phase-advancing light signal to the SCN.PAC1hop receptor activation facilitates catecholamine secretion selectively through 2-APB-sensitive Ca(2+) channels in PC12 cells Discovery of pituitary adenylate cyclase-activating polypeptide-regulated genes through microarray analyses in cell culture and in vivo.Is PACAP the major neurotransmitter for stress transduction at the adrenomedullary synapse?Endogenous PACAP acts as a stress response peptide to protect cerebellar neurons from ethanol or oxidative insult Neuroprotection by endogenous and exogenous PACAP following stroke.Neuropeptides, growth factors, and cytokines: a cohort of informational molecules whose expression is up-regulated by the stress-associated slow transmitter PACAP in chromaffin cells The hop cassette of the PAC1 receptor confers coupling to Ca2+ elevation required for pituitary adenylate cyclase-activating polypeptide-evoked neurosecretion.Analysis of the PC12 cell transcriptome after differentiation with pituitary adenylate cyclase-activating polypeptide (PACAP).Cellular distribution of chromogranin A in excitatory, inhibitory, aminergic and peptidergic neurons of the rodent central nervous system.Inhibition of Ca2+ channels and adrenal catecholamine release by G protein coupled receptors.A visual circuit uses complementary mechanisms to support transient and sustained pupil constriction.Accelerated evolution of the pituitary adenylate cyclase-activating polypeptide precursor gene during human origin PAC1hop, null and hip receptors mediate differential signaling through cyclic AMP and calcium leading to splice variant-specific gene induction in neural cells PACAP is implicated in the stress axes.Pituitary adenylate cyclase-activating polypeptide controls stimulus-transcription coupling in the hypothalamic-pituitary-adrenal axis to mediate sustained hormone secretion during stress.Pituitary adenylate cyclase-activating peptide (PACAP) recruits low voltage-activated T-type calcium influx under acute sympathetic stimulation in mouse adrenal chromaffin cells STC1 induction by PACAP is mediated through cAMP and ERK1/2 but not PKA in cultured cortical neurons Pharmacology and functions of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide: IUPHAR review 1.Whole genome expression profiling associates activation of unfolded protein response with impaired production and release of epinephrine after recurrent hypoglycemia.PACAP intraperitoneal treatment suppresses appetite and food intake via PAC1 receptor in mice by inhibiting ghrelin and increasing GLP-1 and leptin Regulation of angiotensin II type 2 receptor gene expression in the adrenal medulla by acute and repeated immobilization stress.PACAP controls adrenomedullary catecholamine secretion and expression of catecholamine biosynthetic enzymes at high splanchnic nerve firing rates characteristic of stress transduction in male mice Feeding and metabolism in mice lacking pituitary adenylate cyclase-activating polypeptide.Developmental and stress-induced remodeling of cell–cell communication in the adrenal medullary tissue.Stress-induced changes in adrenal neuropeptide Y expression are regulated by a negative feedback loop.PACAP-deficient mice show attenuated corticosterone secretion and fail to develop depressive behavior during chronic social defeat stress.Pituitary adenylate cyclase-activating polypeptide (PACAP) promotes both survival and neuritogenesis in PC12 cells through activation of nuclear factor κB (NF-κB) pathway: involvement of extracellular signal-regulated kinase (ERK), calcium, and c-RE PACAP38 increases vesicular monoamine transporter 2 (VMAT2) expression and attenuates methamphetamine toxicity.Neuropeptide y gates a stress-induced, long-lasting plasticity in the sympathetic nervous system.Discrete signal transduction pathway utilization by a neuropeptide (PACAP) and a cytokine (TNF-alpha) first messenger in chromaffin cells, inferred from coupled transcriptome-promoter analysis of regulated gene cohorts Spatial and activity-dependent catecholamine release in rat adrenal medulla under native neuronal stimulation PACAP regulates immediate catecholamine release from adrenal chromaffin cells in an activity-dependent manner through a protein kinase C-dependent pathway.

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P2860

Pituitary adenylate cyclase-activating polypeptide is a sympathoadrenal neurotransmitter involved in catecholamine regulation and glucohomeostasis

http://www.wikidata.org/entity/Q33898110

description

2001 nî lūn-bûn

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2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2001年の論文

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2001年学术文章

@wuu

2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年學術文章

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name

Pituitary adenylate cyclase-ac ...... egulation and glucohomeostasis

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Pituitary adenylate cyclase-ac ...... egulation and glucohomeostasis

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Pituitary adenylate cyclase-ac ...... egulation and glucohomeostasis

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Pituitary adenylate cyclase-ac ...... egulation and glucohomeostasis

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Pituitary adenylate cyclase-ac ...... egulation and glucohomeostasis

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Proceedings of the National Academy of Sciences of the United States of America

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Pituitary adenylate cyclase-ac ...... egulation and glucohomeostasis

@en

P2093

Carol Hamelink

http://www.w3.org/2001/XMLSchema#string

Eberhard Weihe

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Hyeon-Woo Lee

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Olga Tjurmina

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Ruslan Damadzic

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W Scott Young

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P2860

Visualization of the vesicular acetylcholine transporter in cholinergic nerve terminals and its targeting to a specific population of small synaptic vesicles

Neuropeptides--an overview.

Chemical neuroanatomy of the vesicular amine transporters.

PAC1 receptor-deficient mice display impaired insulinotropic response to glucose and reduced glucose tolerance.

Neural tube expression of pituitary adenylate cyclase-activating peptide (PACAP) and receptor: potential role in patterning and neurogenesis.

Pituitary adenylate cyclase-activating peptide in sensory and autonomic ganglia: localization and regulation.

Cross-communication between acetylcholine and VIP in controlling catecholamine secretion by affecting cAMP, inositol triphosphate, protein kinase C, and calcium in rat adrenal medulla.

Pituitary adenylate cyclase-activating polypeptide may function as a neuromodulator in guinea-pig adrenal medulla.

Comparison of secretion of catecholamines from the rat adrenal medulla during continuous exposure to nicotine, muscarine or excess K.

Activation of tyrosine hydroxylase by pituitary adenylate cyclase-activating polypeptide (PACAP-27) in bovine adrenal chromaffin cells.

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461-466

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scholarly article

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10.1073/PNAS.012608999

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1

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99

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2001-12-26T00:00:00Z

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11600463

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11756684

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neurotransmitter

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117582

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