Decomposing the energetic impact of drug resistant mutations in HIV-1 protease on binding DRV.
about
Rational approaches to improving selectivity in drug designStructural and Thermodynamic Basis of Amprenavir/Darunavir and Atazanavir Resistance in HIV-1 Protease with Mutations at Residue 50Substrate Envelope-Designed Potent HIV-1 Protease Inhibitors to Avoid Drug ResistanceDrug Resistance Conferred by Mutations Outside the Active Site through Alterations in the Dynamic and Structural Ensemble of HIV-1 ProteaseEfficient Computation of Small-Molecule Configurational Binding Entropy and Free Energy Changes by Ensemble EnumerationProteochemometric modeling of the bioactivity spectra of HIV-1 protease inhibitors by introducing protein-ligand interaction fingerprintComparing aminoglycoside binding sites in bacterial ribosomal RNA and aminoglycoside modifying enzymes.Drug Resistance Mutations Alter Dynamics of Inhibitor-Bound HIV-1 Protease.Molecular Basis for Drug Resistance in HIV-1 ProteaseEffects of drug-resistant mutations on the dynamic properties of HIV-1 protease and inhibition by Amprenavir and Darunavir.Interaction of I50V mutant and I50L/A71V double mutant HIV-protease with inhibitor TMC114 (darunavir): molecular dynamics simulation and binding free energy studies.Interdependence of Inhibitor Recognition in HIV-1 Protease.Differential Flap Dynamics in Wild-type and a Drug Resistant Variant of HIV-1 Protease Revealed by Molecular Dynamics and NMR Relaxation.Effect of polarization on HIV-1protease and fluoro-substituted inhibitors binding energies by large scale molecular dynamics simulations.SAR and Lead Optimization of an HIV-1 Vif-APOBEC3G Axis Inhibitor.Simulation study of the ability of a computationally-designed peptide to recognize target tRNALys3 and other decoy tRNAs.A potential in vitro and in vivo anti-HIV drug screening system for Chinese herbal medicines.
P2860
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P2860
Decomposing the energetic impact of drug resistant mutations in HIV-1 protease on binding DRV.
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Decomposing the energetic impa ...... HIV-1 protease on binding DRV.
@ast
Decomposing the energetic impa ...... HIV-1 protease on binding DRV.
@en
type
label
Decomposing the energetic impa ...... HIV-1 protease on binding DRV.
@ast
Decomposing the energetic impa ...... HIV-1 protease on binding DRV.
@en
prefLabel
Decomposing the energetic impa ...... HIV-1 protease on binding DRV.
@ast
Decomposing the energetic impa ...... HIV-1 protease on binding DRV.
@en
P2860
P356
P1476
Decomposing the energetic impa ...... HIV-1 protease on binding DRV.
@en
P2093
Celia A Schiffer
Yufeng Cai
P2860
P304
P356
10.1021/CT9004678
P577
2010-04-01T00:00:00Z