Retinal very long-chain PUFAs: new insights from studies on ELOVL4 protein - Wikidata - wikimedia - TriplyDB

Retinal very long-chain PUFAs: new insights from studies on ELOVL4 protein

Retinal very long-chain PUFAs: new insights from studies on ELOVL4 protein

http://www.wikidata.org/entity/Q33902007

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Effects on vesicular transport pathways at the late endosome in cells with limited very long-chain fatty acids.Ablation of retinal ciliopathy protein RPGR results in altered photoreceptor ciliary composition Two modes of regulation of the fatty acid elongase ELOVL6 by the 3-ketoacyl-CoA reductase KAR in the fatty acid elongation cycle Lipidomics of human Meibomian gland secretions: Chemistry, biophysics, and physiological role of Meibomian lipids Distribution of ELOVL4 in the Developing and Adult Mouse Brain.Why has Nature Chosen Lutein and Zeaxanthin to Protect the Retina?Functional characterization and differential nutritional regulation of putative Elovl5 and Elovl4 elongases in large yellow croaker (Larimichthys crocea).Elovanoids are novel cell-specific lipid mediators necessary for neuroprotective signaling for photoreceptor cell integrity Endoplasmic reticulum stress and the unfolded protein responses in retinal degeneration.Long-chain and very long-chain polyunsaturated fatty acids in ocular aging and age-related macular degeneration High resolution MALDI imaging mass spectrometry of retinal tissue lipids.Chemical synthesis of deuterium-labeled and unlabeled very long chain polyunsaturated fatty acids Metabolism of very long-chain Fatty acids: genes and pathophysiology.Role of membrane integrity on G protein-coupled receptors: Rhodopsin stability and function.Association of n3 and n6 polyunsaturated fatty acids in red blood cell membrane and plasma with severity of normal tension glaucoma.ELOVL4 protein preferentially elongates 20:5n3 to very long chain PUFAs over 20:4n6 and 22:6n3 Essential role of ELOVL4 protein in very long chain fatty acid synthesis and retinal function.Omega-3 fatty acids cause dramatic changes in TLR4 and purinergic eicosanoid signaling.Applications of mass spectrometry to lipids and membranes Serum levels of lipid metabolites in age-related macular degeneration.Associations of human retinal very long-chain polyunsaturated fatty acids with dietary lipid biomarkers.Role of ELOVL4 and very long-chain polyunsaturated fatty acids in mouse models of Stargardt type 3 retinal degeneration.Can Xanthophyll-Membrane Interactions Explain Their Selective Presence in the Retina and Brain?Mutation for nonsyndromic mental retardation in the trans-2-enoyl-CoA reductase TER gene involved in fatty acid elongation impairs the enzyme activity and stability, leading to change in sphingolipid profile Spatial organization of lipids in the human retina and optic nerve by MALDI imaging mass spectrometry.Insights from Genetic Model Systems of Retinal Degeneration: Role of Epsins in Retinal Angiogenesis and VEGFR2 Signaling.Endoplasmic reticulum microenvironment and conserved histidines govern ELOVL4 fatty acid elongase activity.Isolation and characterization of the diatom Phaeodactylum Δ5-elongase gene for transgenic LC-PUFA production in Pichia pastoris.Biosynthesis of Polyunsaturated Fatty Acids in Octopus vulgaris: Molecular Cloning and Functional Characterisation of a Stearoyl-CoA Desaturase and an Elongation of Very Long-Chain Fatty Acid 4 Protein.Expanding the horizons of lipidomics. Towards fluxolipidomics.Meibomian glands, meibum, and meibogenesis.Hetero-oligomeric interactions of an ELOVL4 mutant protein: implications in the molecular mechanism of Stargardt-3 macular dystrophy.Lorenzo's oil inhibits ELOVL1 and lowers the level of sphingomyelin with a saturated very long-chain fatty acid Elongation of very Long-Chain (>C24) Fatty Acids in Clarias gariepinus: Cloning, Functional Characterization and Tissue Expression of elovl4 Elongases Protective effect of resveratrol against light-induced retinal degeneration in aged SAMP8 mice.Elovl4 5-bp deletion does not accelerate cone photoreceptor degeneration in an all-cone mouse.Retinal energy demands control vascular supply of the retina in development and disease: The role of neuronal lipid and glucose metabolism.Retinal de novo lipogenesis coordinates neurotrophic signaling to maintain vision.Deficiency of a Retinal Dystrophy Protein, Acyl-CoA Binding Domain-containing 5 (ACBD5), Impairs Peroxisomal β-Oxidation of Very-long-chain Fatty Acids.Etiology and treatment of adrenoleukodystrophy: new insights from Drosophila.

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Retinal very long-chain PUFAs: new insights from studies on ELOVL4 protein

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2010 nî lūn-bûn

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2010 թուականի Մարտին հրատարակուած գիտական յօդուած

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2010 թվականի մարտին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Retinal very long-chain PUFAs: new insights from studies on ELOVL4 protein

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Retinal very long-chain PUFAs: new insights from studies on ELOVL4 protein

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Retinal very long-chain PUFAs: new insights from studies on ELOVL4 protein

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Retinal very long-chain PUFAs: new insights from studies on ELOVL4 protein

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Retinal very long-chain PUFAs: new insights from studies on ELOVL4 protein

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Retinal very long-chain PUFAs: new insights from studies on ELOVL4 protein

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Journal of Lipid Research

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Retinal very long-chain PUFAs: new insights from studies on ELOVL4 protein

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Martin-Paul Agbaga

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Md Nawajes A Mandal

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Robert E Anderson

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P2860

A 5-bp deletion in ELOVL4 is associated with two related forms of autosomal dominant macular dystrophy

The role of ELOVL1 in very long-chain fatty acid homeostasis and X-linked adrenoleukodystrophy

Dominant negative mechanism underlies autosomal dominant Stargardt-like macular dystrophy linked to mutations in ELOVL4

Identification and expression of mammalian long-chain PUFA elongation enzymes

A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy

Novel lipogenic enzyme ELOVL7 is involved in prostate cancer growth through saturated long-chain fatty acid metabolism

Cloning of a human cDNA encoding a novel enzyme involved in the elongation of long-chain polyunsaturated fatty acids

Neuroprotectin D1: a docosahexaenoic acid-derived docosatriene protects human retinal pigment epithelial cells from oxidative stress

Retinal pathology and skin barrier defect in mice carrying a Stargardt disease-3 mutation in elongase of very long chain fatty acids-4

The Meibomian puzzle: combining pieces together

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1624-1642

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10.1194/JLR.R005025

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7

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51

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2882734

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