Cooperative interaction of Etv2 and Gata2 regulates the development of endothelial and hematopoietic lineages
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The ETS Factor, ETV2: a Master Regulator for Vascular Endothelial Cell DevelopmentLost in translation: pluripotent stem cell-derived hematopoiesisKelch Repeat and BTB Domain Containing Protein 5 (Kbtbd5) Regulates Skeletal Muscle Myogenesis through the E2F1-DP1 ComplexDirect induction of haematoendothelial programs in human pluripotent stem cells by transcriptional regulators.Notch1 acts via Foxc2 to promote definitive hematopoiesis via effects on hemogenic endothelium.Human disease modeling reveals integrated transcriptional and epigenetic mechanisms of NOTCH1 haploinsufficiency.The transcription factor Mesp1 interacts with cAMP-responsive element binding protein 1 (Creb1) and coactivates Ets variant 2 (Etv2) gene expression.Induction of hematopoietic and endothelial cell program orchestrated by ETS transcription factor ER71/ETV2.Feedback Mechanisms Regulate Ets Variant 2 (Etv2) Gene Expression and Hematoendothelial Lineages.Significant improvement of direct reprogramming efficacy of fibroblasts into progenitor endothelial cells by ETV2 and hypoxia.Genetic redundancy of GATA factors in the extraembryonic trophoblast lineage ensures the progression of preimplantation and postimplantation mammalian development.An arterial-specific enhancer of the human endothelin converting enzyme 1 (ECE1) gene is synergistically activated by Sox17, FoxC2, and Etv2.The Etv2-miR-130a Network Regulates Mesodermal Specification.Differentiation of pluripotent stem cells into endothelial cells.Dynamically and epigenetically coordinated GATA/ETS/SOX transcription factor expression is indispensable for endothelial cell differentiation.Extracellular vesicles of ETV2 transfected fibroblasts stimulate endothelial cells and improve neovascularization in a murine model of hindlimb ischemia.Etv2 IS A MASTER REGULATOR OF HEMATOENDOTHELIAL LINEAGES.Embryonic Stem Cell Differentiation to Functional Arterial Endothelial Cells through Sequential Activation of ETV2 and NOTCH1 Signaling by HIF1α.Etv2-miR-130a-Jarid2 cascade regulates vascular patterning during embryogenesis.iPSCs-based generation of vascular cells: reprogramming approaches and applications.IP3R-mediated Ca2+ signals govern hematopoietic and cardiac divergence of Flk1+ cells via the calcineurin-NFATc3-Etv2 pathway.Etv2 as an essential regulator of mesodermal lineage development.Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program.
P2860
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P2860
Cooperative interaction of Etv2 and Gata2 regulates the development of endothelial and hematopoietic lineages
description
2014 nî lūn-bûn
@nan
2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Cooperative interaction of Etv ...... ial and hematopoietic lineages
@ast
Cooperative interaction of Etv ...... ial and hematopoietic lineages
@en
type
label
Cooperative interaction of Etv ...... ial and hematopoietic lineages
@ast
Cooperative interaction of Etv ...... ial and hematopoietic lineages
@en
prefLabel
Cooperative interaction of Etv ...... ial and hematopoietic lineages
@ast
Cooperative interaction of Etv ...... ial and hematopoietic lineages
@en
P2093
P2860
P1476
Cooperative interaction of Etv ...... ial and hematopoietic lineages
@en
P2093
Daniel J Garry
Jai Richard
Jamie A Thomson
Katie M Zirbes
Naoko Koyano-Nakagawa
Wuming Gong
Xiaozhong Shi
P2860
P304
P356
10.1016/J.YDBIO.2014.02.018
P407
P577
2014-02-26T00:00:00Z