Impaired Akt activity down-modulation, caspase-3 activation, and apoptosis in cells expressing a caspase-resistant mutant of RasGAP at position 157
about
Revisiting G3BP1 as a RasGAP binding protein: sensitization of tumor cells to chemotherapy by the RasGAP 317-326 sequence does not involve G3BP1RasGAP-derived fragment N increases the resistance of beta cells towards apoptosis in NOD mice and delays the progression from mild to overt diabetes.Role of mTOR, Bad, and Survivin in RasGAP Fragment N-Mediated Cell ProtectionRasGAP Shields Akt from Deactivating Phosphatases in Fibroblast Growth Factor Signaling but Loses This Ability Once Cleaved by Caspase-3.Role and mechanism of hypoxia-inducible factor-1 in cell growth and apoptosis of breast cancer cell line MDA-MB-231Caspase-3 protects stressed organs against cell deathExpression of the NH(2)-terminal fragment of RasGAP in pancreatic beta-cells increases their resistance to stresses and protects mice from diabetes.Fragment N2, a caspase-3-generated RasGAP fragment, inhibits breast cancer metastatic progression.Inhibition of cell migration and invasion mediated by the TAT-RasGAP317-326 peptide requires the DLC1 tumor suppressor.Hip is a pro-survival substrate of granzyme B.Expression of an uncleavable N-terminal RasGAP fragment in insulin-secreting cells increases their resistance toward apoptotic stimuli without affecting their glucose-induced insulin secretion.
P2860
Q21134929-68D7BAAD-A5F8-4EF4-B15C-2362907EC087Q31028641-1C9E5F9F-3DDB-4FDF-A212-D0485CA2AC60Q34797799-BE6AB597-C61F-4560-A120-067CE95C605BQ35925830-6FED9219-A11F-4A4D-9ECB-1E1CE153DD4AQ36216542-00CCC6D4-B79F-443C-B223-F59EE0977EE7Q36362940-6D7AC9ED-169B-45B2-8629-B1051F24D5EDQ37400767-FDE1B1DD-F80D-4FFA-9C61-17A01BD59348Q39042469-6F76ACEF-6516-468E-BCD4-797A5A981510Q39064888-C4EDDB91-FF68-4377-BDC5-C82135803A6FQ40109524-B97DE1AE-8DCF-407A-8CEE-45912BE41C54Q40392908-3D07DE90-B627-401D-A471-81BCE395FAFE
P2860
Impaired Akt activity down-modulation, caspase-3 activation, and apoptosis in cells expressing a caspase-resistant mutant of RasGAP at position 157
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Impaired Akt activity down-mod ...... tant of RasGAP at position 157
@ast
Impaired Akt activity down-mod ...... tant of RasGAP at position 157
@en
type
label
Impaired Akt activity down-mod ...... tant of RasGAP at position 157
@ast
Impaired Akt activity down-mod ...... tant of RasGAP at position 157
@en
prefLabel
Impaired Akt activity down-mod ...... tant of RasGAP at position 157
@ast
Impaired Akt activity down-mod ...... tant of RasGAP at position 157
@en
P2093
P2860
P356
P1476
Impaired Akt activity down-mod ...... tant of RasGAP at position 157
@en
P2093
David Michod
Gilles Dubuis
Jiang-Yan Yang
Joël Walicki
P2860
P304
P356
10.1091/MBC.E05-01-0080
P577
2005-05-18T00:00:00Z