Cloning and characterization of human histone deacetylase 8.
about
Cloning and characterization of a histone deacetylase, HDAC9Identification of HDAC10, a novel class II human histone deacetylase containing a leucine-rich domainTranscriptional regulation by the repressor of estrogen receptor activity via recruitment of histone deacetylasesCloning and functional characterization of HDAC11, a novel member of the human histone deacetylase familyHistone deacetylases (HDACs): characterization of the classical HDAC familyHistone deacetylase 4 possesses intrinsic nuclear import and export signalsNegative regulation of histone deacetylase 8 activity by cyclic AMP-dependent protein kinase AEvolution of the arginase fold and functional diversityExpression of histone deacetylase 8, a class I histone deacetylase, is restricted to cells showing smooth muscle differentiation in normal human tissuesHistone deacetylase 8 safeguards the human ever-shorter telomeres 1B (hEST1B) protein from ubiquitin-mediated degradationHDAC8 substrates: Histones and beyondHuman class I histone deacetylase complexes show enhanced catalytic activity in the presence of ATP and co-immunoprecipitate with the ATP-dependent chaperone protein Hsp70HAT2 mediates histone H4K4 acetylation and affects micrococcal nuclease sensitivity of chromatin in Leishmania donovani.miR-93 suppresses proliferation and colony formation of human colon cancer stem cells.Recruitment of histone deacetylase 3 to the interferon-A gene promoters attenuates interferon expressionLoss of Sin3/Rpd3 histone deacetylase restores the DNA damage response in checkpoint-deficient strains of Saccharomyces cerevisiae.An enzyme-coupled assay measuring acetate production for profiling histone deacetylase specificity.Pharmacological induction of fetal hemoglobin synthesis using histone deacetylase inhibitors.Targeting Histone Deacetylases in Diseases: Where Are We?Differential effects of histone deacetylase inhibitors in tumor and normal cells-what is the toxicological relevance?Regain control of p53: Targeting leukemia stem cells by isoform-specific HDAC inhibitionResidues in the 11 A channel of histone deacetylase 1 promote catalytic activity: implications for designing isoform-selective histone deacetylase inhibitors.Mutagenesis studies of the 14 Å internal cavity of histone deacetylase 1: insights toward the acetate-escape hypothesis and selective inhibitor design.HDAC8 functions in spindle assembly during mouse oocyte meiosis.Modulation of antigen-presenting cells by HDAC inhibitors: implications in autoimmunity and cancer.Transcription and beyond: the role of mammalian class I lysine deacetylasesTargeting histone deacetylases: a novel approach in Parkinson's disease.Targeting histone deacetylase 8 as a therapeutic approach to cancer and neurodegenerative diseases.Histone deacetylase 8 is deregulated in urothelial cancer but not a target for efficient treatment.Expression of class I histone deacetylases during chick and mouse development.The Metal Drives the Chemistry: Dual Functions of Acireductone Dioxygenase.KDAC8 substrate specificity quantified by a biologically relevant, label-free deacetylation assay.A histone deacetylase-dependent screen in yeast.Inactivating mutation in histone deacetylase 3 stabilizes its active conformation.Scaffold dependent histone deacetylase (HDAC) inhibitor induced re-equilibration of the subcellular localization and post-translational modification state of class I HDACsPure curcumin increases the expression of SOCS1 and SOCS3 in myeloproliferative neoplasms through suppressing class I histone deacetylases.Structure-activity relationships of hydroxamate-based histone deacetylase-8 inhibitors: reality behind anticancer drug discovery.HDAC8 substrate selectivity is determined by long- and short-range interactions leading to enhanced reactivity for full-length histone substrates compared with peptides.HDAC8 regulates long-term hematopoietic stem-cell maintenance under stress by modulating p53 activity.Overexpressed HDAC8 in cervical cancer cells shows functional redundancy of tubulin deacetylation with HDAC6.
P2860
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P2860
Cloning and characterization of human histone deacetylase 8.
description
2000 nî lūn-bûn
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2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Cloning and characterization of human histone deacetylase 8.
@ast
Cloning and characterization of human histone deacetylase 8.
@en
type
label
Cloning and characterization of human histone deacetylase 8.
@ast
Cloning and characterization of human histone deacetylase 8.
@en
prefLabel
Cloning and characterization of human histone deacetylase 8.
@ast
Cloning and characterization of human histone deacetylase 8.
@en
P2093
P1433
P1476
Cloning and characterization of human histone deacetylase 8.
@en
P2093
Van den Wyngaert I
Verhasselt P
de Vries W
P356
10.1016/S0014-5793(00)01813-5
P407
P577
2000-07-01T00:00:00Z