NF-κB essential modulator (NEMO) interaction with linear and lys-63 ubiquitin chains contributes to NF-κB activation
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Ubiquitin modificationsMisframed ubiquitin and impaired protein quality control: an early event in Alzheimer's diseaseRegulation of NF-κB by ubiquitinationSuper-resolution microscopy reveals a preformed NEMO lattice structure that is collapsed in incontinentia pigmentiUBXD Proteins: A Family of Proteins with Diverse Functions in CancerMolecular basis for specificity of the Met1-linked polyubiquitin signalQuantification of cellular NEMO content and its impact on NF-κB activation by genotoxic stressArabidopsis ALIX is required for the endosomal localization of the deubiquitinating enzyme AMSH3.Individual Src-family tyrosine kinases direct the degradation or protection of the clock protein Timeless via differential ubiquitylation.YOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-κBOncogenic CARMA1 couples NF-κB and β-catenin signaling in diffuse large B-cell lymphomas.Alternative splicing of MALT1 controls signalling and activation of CD4(+) T cellsNF-κB Pathway in Autoinflammatory Diseases: Dysregulation of Protein Modifications by Ubiquitin Defines a New Category of Autoinflammatory Diseases.Kaposi's sarcoma associated herpesvirus encoded viral FLICE inhibitory protein K13 activates NF-κB pathway independent of TRAF6, TAK1 and LUBAC.The IκB kinase complex in NF-κB regulation and beyond.Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies.Protein-protein interaction modulator drug discovery: past efforts and future opportunities using a rich source of low- and high-throughput screening assays.CYLD-mediated signaling and diseases.Inhibition of Canonical NF-κB Signaling by a Small Molecule Targeting NEMO-Ubiquitin InteractionSHARPIN is a key regulator of immune and inflammatory responsesLegume receptors perceive the rhizobial lipochitin oligosaccharide signal molecules by direct binding.Diversification of the structural determinants of fibroblast growth factor-heparin interactions: implications for binding specificityRecruitment of A20 by the C-terminal domain of NEMO suppresses NF-κB activation and autoinflammatory disease.Ubiquitin regulates caspase recruitment domain-mediated signaling by nucleotide-binding oligomerization domain-containing proteins NOD1 and NOD2.A20/TNFAIP3 inhibits NF-κB activation induced by the Kaposi's sarcoma-associated herpesvirus vFLIP oncoprotein.Ubiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB1.EGLN3 inhibition of NF-κB is mediated by prolyl hydroxylase-independent inhibition of IκB kinase γ ubiquitinationInnate immune-directed NF-κB signaling requires site-specific NEMO ubiquitination.Deficiency in p53 is required for doxorubicin induced transcriptional activation of NF-кB target genes in human breast cancerProtein Quality Control by Molecular Chaperones in Neurodegeneration.Ubiquitin pathways in neurodegenerative disease.Formation and removal of poly-ubiquitin chains in the regulation of tumor necrosis factor-induced gene activation and cell death.Molluscum Contagiosum Virus MC159 Abrogates cIAP1-NEMO Interactions and Inhibits NEMO Polyubiquitination.Mutation of nonessential cysteines shows that the NF-κB essential modulator forms a constitutive noncovalent dimer that binds IκB kinase-β with high affinity.Recruitment of TBK1 to cytosol-invading Salmonella induces WIPI2-dependent antibacterial autophagy.Analysis of nuclear factor-κB (NF-κB) essential modulator (NEMO) binding to linear and lysine-linked ubiquitin chains and its role in the activation of NF-κB.Two-sided ubiquitin binding of NF-κB essential modulator (NEMO) zinc finger unveiled by a mutation associated with anhidrotic ectodermal dysplasia with immunodeficiency syndrome.Target specificity of the E3 ligase LUBAC for ubiquitin and NEMO relies on different minimal requirements.Molecular Determinants of Scaffold-induced Linear Ubiquitinylation of B Cell Lymphoma/Leukemia 10 (Bcl10) during T Cell Receptor and Oncogenic Caspase Recruitment Domain-containing Protein 11 (CARD11) Signaling.The IKK/NF-κB signaling pathway requires Morgana to drive breast cancer metastasis.
P2860
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P2860
NF-κB essential modulator (NEMO) interaction with linear and lys-63 ubiquitin chains contributes to NF-κB activation
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
name
NF-κB essential modulator (NEM ...... ontributes to NF-κB activation
@ast
NF-κB essential modulator (NEM ...... ontributes to NF-κB activation
@en
type
label
NF-κB essential modulator (NEM ...... ontributes to NF-κB activation
@ast
NF-κB essential modulator (NEM ...... ontributes to NF-κB activation
@en
prefLabel
NF-κB essential modulator (NEM ...... ontributes to NF-κB activation
@ast
NF-κB essential modulator (NEM ...... ontributes to NF-κB activation
@en
P2093
P2860
P50
P356
P1476
NF-κB essential modulator (NEM ...... ontributes to NF-κB activation
@en
P2093
Daniel Nagel
Marc Schmidt-Supprian
Moritz Metlitzky
Richard A Griesbach
Scarlett Dornauer
Tim M Wanger
Wolfgang Beisker
P2860
P304
26107-26117
P356
10.1074/JBC.M111.233163
P407
P577
2011-05-26T00:00:00Z