Smooth muscle and skeletal muscle myosins produce similar unitary forces and displacements in the laser trap
about
Human actin mutations associated with hypertrophic and dilated cardiomyopathies demonstrate distinct thin filament regulatory properties in vitroMechanics of actomyosin bonds in different nucleotide states are tuned to muscle contractionPoorly understood aspects of striated muscle contractionSkeletal muscle myofilament adaptations to aging, disease, and disuse and their effects on whole muscle performance in older adult humansTumor cell migration in complex microenvironmentsVisualizing key hinges and a potential major source of compliance in the lever arm of myosinSmooth muscle myosin heavy chain isoforms and their role in muscle physiologyThe myosin power strokeCoiled-coil unwinding at the smooth muscle myosin head-rod junction is required for optimal mechanical performance.Myosin V exhibits a high duty cycle and large unitary displacementCardiac myosin missense mutations cause dilated cardiomyopathy in mouse models and depress molecular motor function.Loop 2 of myosin is a force-dependent inhibitor of the rigor bondThe Effects of Load on E-Selectin Bond Rupture and Bond Formation.Phosphorylation of tropomyosin extends cooperative binding of myosin beyond a single regulatory unitThe molecular mechanics of P- and L-selectin lectin domains binding to PSGL-1Determinants of plasma membrane wounding by deforming stressLoad and Pi control flux through the branched kinetic cycle of myosin V.A mutant heterodimeric myosin with one inactive head generates maximal displacement.Hidden-Markov methods for the analysis of single-molecule actomyosin displacement data: the variance-Hidden-Markov methodKinetic differences at the single molecule level account for the functional diversity of rabbit cardiac myosin isoforms.The biochemical kinetics underlying actin movement generated by one and many skeletal muscle myosin moleculesThe unique properties of tonic smooth muscle emerge from intrinsic as well as intermolecular behaviors of Myosin molecules.Regulatory and essential light chains of myosin rotate equally during contraction of skeletal muscle.Molecular mechanics of two smooth muscle heavy meromyosin constructs that differ by an insert in the motor domain.Single molecule biochemistry using optical tweezers.Myosin conformational states determined by single fluorophore polarizationThe converter domain modulates kinetic properties of Drosophila myosin.Single-myosin crossbridge interactions with actin filaments regulated by troponin-tropomyosin.Resource Letter: LBOT-1: Laser-based optical tweezersIntegrated multimodal microscopy, time-resolved fluorescence, and optical-trap rheometry: toward single molecule mechanobiology.Hypertrophic and dilated cardiomyopathy mutations differentially affect the molecular force generation of mouse alpha-cardiac myosin in the laser trap assay.Single molecule measurements and molecular motorsEffect of low pH on single skeletal muscle myosin mechanics and kineticsAffinity for MgADP and force of unbinding from actin of myosin purified from tonic and phasic smooth muscle.Myosin-10 produces its power-stroke in two phases and moves processively along a single actin filament under low load.Biomechanics, one molecule at a time.Simultaneous observation of tail and head movements of myosin V during processive motion.Molecular model of muscle contraction.Single-motor mechanics and models of the myosin motorCooperativity of myosin molecules through strain-dependent chemistry.
P2860
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P2860
Smooth muscle and skeletal muscle myosins produce similar unitary forces and displacements in the laser trap
description
1997 nî lūn-bûn
@nan
1997 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մարտին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Smooth muscle and skeletal mus ...... isplacements in the laser trap
@ast
Smooth muscle and skeletal mus ...... isplacements in the laser trap
@en
type
label
Smooth muscle and skeletal mus ...... isplacements in the laser trap
@ast
Smooth muscle and skeletal mus ...... isplacements in the laser trap
@en
prefLabel
Smooth muscle and skeletal mus ...... isplacements in the laser trap
@ast
Smooth muscle and skeletal mus ...... isplacements in the laser trap
@en
P2093
P2860
P1433
P1476
Smooth muscle and skeletal mus ...... isplacements in the laser trap
@en
P2093
P2860
P304
P356
10.1016/S0006-3495(97)78753-8
P407
P577
1997-03-01T00:00:00Z