Autophagy, cytoplasm-to-vacuole targeting pathway, and pexophagy in yeast and mammalian cells.
about
The human homolog of Saccharomyces cerevisiae Apg7p is a Protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3The dynamin-like GTPase DLP1 is essential for peroxisome division and is recruited to peroxisomes in part by PEX11A mammalian autophagosome maturation mechanism mediated by TECPR1 and the Atg12-Atg5 conjugateHuman autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagyS100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3WIPI-1alpha (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagyThe intermediate filament protein, vimentin, is a regulator of NOD2 activityInhibition of macroautophagy triggers apoptosisSubversion of cellular autophagosomal machinery by RNA viruses.Autophagy in the eukaryotic cellPEX11alpha is required for peroxisome proliferation in response to 4-phenylbutyrate but is dispensable for peroxisome proliferator-activated receptor alpha-mediated peroxisome proliferationCooperative binding of the cytoplasm to vacuole targeting pathway proteins, Cvt13 and Cvt20, to phosphatidylinositol 3-phosphate at the pre-autophagosomal structure is required for selective autophagyCvt9/Gsa9 functions in sequestering selective cytosolic cargo destined for the vacuoleALS-associated mutant SOD1G93A causes mitochondrial vacuolation by expansion of the intermembrane space and by involvement of SOD1 aggregation and peroxisomesQuantitative genomics of starvation stress resistance in DrosophilaEvolution of energy metabolism and its compartmentation in KinetoplastidaTetrandrine, a Chinese plant-derived alkaloid, is a potential candidate for cancer chemotherapyMetamorphoses of malaria: the role of autophagy in parasite differentiationNovel PtdIns(3)P-binding protein Etf1 functions as an effector of the Vps34 PtdIns 3-kinase in autophagy.Microautophagic vacuole invagination requires calmodulin in a Ca2+-independent function.The Vid vesicle to vacuole trafficking event requires components of the SNARE membrane fusion machinery.Trs85 (Gsg1), a component of the TRAPP complexes, is required for the organization of the preautophagosomal structure during selective autophagy via the Cvt pathway.Antagonistic controls of autophagy and glycogen accumulation by Snf1p, the yeast homolog of AMP-activated protein kinase, and the cyclin-dependent kinase Pho85p.Cvt19 is a receptor for the cytoplasm-to-vacuole targeting pathway.Atg17 regulates the magnitude of the autophagic response.Degradation of lipid vesicles in the yeast vacuole requires function of Cvt17, a putative lipaseCvt18/Gsa12 is required for cytoplasm-to-vacuole transport, pexophagy, and autophagy in Saccharomyces cerevisiae and Pichia pastoris.Cyclophilin A mediates Vid22p function in the import of fructose-1,6-bisphosphatase into Vid vesicles.Intravacuolar membrane lysis in Saccharomyces cerevisiae. Does vacuolar targeting of Cvt17/Aut5p affect its function?Apg2 is a novel protein required for the cytoplasm to vacuole targeting, autophagy, and pexophagy pathways.The type 1 phosphatase Reg1p-Glc7p is required for the glucose-induced degradation of fructose-1,6-bisphosphatase in the vacuole.The Ccz1-Mon1 protein complex is required for the late step of multiple vacuole delivery pathways.Atg22 recycles amino acids to link the degradative and recycling functions of autophagy.Yol082p, a novel CVT protein involved in the selective targeting of aminopeptidase I to the yeast vacuole.Atg21 is required for effective recruitment of Atg8 to the preautophagosomal structure during the Cvt pathway.Membrane recruitment of Aut7p in the autophagy and cytoplasm to vacuole targeting pathways requires Aut1p, Aut2p, and the autophagy conjugation complexApg2p functions in autophagosome formation on the perivacuolar structure.Sorting of proteins into multivesicular bodies: ubiquitin-dependent and -independent targetingChemical genetic analysis of Apg1 reveals a non-kinase role in the induction of autophagy.Ccz1p/Aut11p/Cvt16p is essential for autophagy and the cvt pathway.
P2860
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P2860
Autophagy, cytoplasm-to-vacuole targeting pathway, and pexophagy in yeast and mammalian cells.
description
2000 nî lūn-bûn
@nan
2000 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Autophagy, cytoplasm-to-vacuol ...... in yeast and mammalian cells.
@ast
Autophagy, cytoplasm-to-vacuol ...... in yeast and mammalian cells.
@en
type
label
Autophagy, cytoplasm-to-vacuol ...... in yeast and mammalian cells.
@ast
Autophagy, cytoplasm-to-vacuol ...... in yeast and mammalian cells.
@en
prefLabel
Autophagy, cytoplasm-to-vacuol ...... in yeast and mammalian cells.
@ast
Autophagy, cytoplasm-to-vacuol ...... in yeast and mammalian cells.
@en
P1476
Autophagy, cytoplasm-to-vacuol ...... in yeast and mammalian cells.
@en
P2093
P304
P356
10.1146/ANNUREV.BIOCHEM.69.1.303
P577
2000-01-01T00:00:00Z