Binding of the MLL PHD3 finger to histone H3K4me3 is required for MLL-dependent gene transcription.
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Systematic Classification of Mixed-Lineage Leukemia Fusion Partners Predicts Additional Cancer PathwaysRecent progress toward epigenetic therapies: the example of mixed lineage leukemiaAn unexpected journey: lysine methylation across the proteomeConcise review: Leukemia stem cells in personalized medicineDiverse functions of PHD fingers of the MLL/KMT2 subfamilyThe PHD3 domain of MLL acts as a CYP33-regulated switch between MLL-mediated activation and repression .TrxG and PcG proteins but not methylated histones remain associated with DNA through replication.A mutation screen in patients with Kabuki syndrome.The molecular mechanics of mixed lineage leukemia.The chromatin signaling pathway: diverse mechanisms of recruitment of histone-modifying enzymes and varied biological outcomes.The MLL recombinome of acute leukemias in 2013.Proteolytically cleaved MLL subunits are susceptible to distinct degradation pathways.Handpicking epigenetic marks with PHD fingers.ECSASB2 mediates MLL degradation during hematopoietic differentiationHistone recognition and nuclear receptor co-activator functions of Drosophila cara mitad, a homolog of the N-terminal portion of mammalian MLL2 and MLL3The pathogenesis of mixed-lineage leukemia.Molecular Insights into Inhibition of the Methylated Histone-Plant Homeodomain Complexes by Calixarenes.Tandem PHD fingers of MORF/MOZ acetyltransferases display selectivity for acetylated histone H3 and are required for the association with chromatinA subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.ZF-CxxC domain-containing proteins, CpG islands and the chromatin connection.MLL fusion protein-driven AML is selectively inhibited by targeted disruption of the MLL-PAFc interaction.Trithorax monomethylates histone H3K4 and interacts directly with CBP to promote H3K27 acetylation and antagonize Polycomb silencing.Combinatorial readout of dual histone modifications by paired chromatin-associated modules.Epigenetics and blood disorders.Menin as a hub controlling mixed lineage leukemia.The role of chromatin modifiers in normal and malignant hematopoiesisMolecular and Epigenetic Mechanisms of MLL in Human Leukemogenesis.Mechanisms of mixed-lineage leukemia.Structural biology-based insights into combinatorial readout and crosstalk among epigenetic marks.Histone target selection within chromatin: an exemplary case of teamwork.The MLL recombinome of acute leukemias in 2017.The Mi-2 homolog Mit1 actively positions nucleosomes within heterochromatin to suppress transcription.Interaction of SET domains with histones and nucleic acid structures in active chromatin.Evolution of AF6-RAS association and its implications in mixed-lineage leukemia.Traceless Synthesis of Asymmetrically Modified Bivalent Nucleosomes.CHARGE and Kabuki syndromes: a phenotypic and molecular link.Identification of two independent nucleosome-binding domains in the transcriptional co-activator SPBP
P2860
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P2860
Binding of the MLL PHD3 finger to histone H3K4me3 is required for MLL-dependent gene transcription.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
name
Binding of the MLL PHD3 finger ...... -dependent gene transcription.
@ast
Binding of the MLL PHD3 finger ...... -dependent gene transcription.
@en
type
label
Binding of the MLL PHD3 finger ...... -dependent gene transcription.
@ast
Binding of the MLL PHD3 finger ...... -dependent gene transcription.
@en
prefLabel
Binding of the MLL PHD3 finger ...... -dependent gene transcription.
@ast
Binding of the MLL PHD3 finger ...... -dependent gene transcription.
@en
P2093
P2860
P1476
Binding of the MLL PHD3 finger ...... -dependent gene transcription.
@en
P2093
Catherine A Musselman
Michael L Cleary
Pei-Yun Chang
Robert A Hom
Tatiana G Kutateladze
P2860
P304
P356
10.1016/J.JMB.2010.05.005
P577
2010-05-07T00:00:00Z