NrasG12D oncoprotein inhibits apoptosis of preleukemic cells expressing Cbfβ-SMMHC via activation of MEK/ERK axis. - Wikidata - wikimedia - TriplyDB

NrasG12D oncoprotein inhibits apoptosis of preleukemic cells expressing Cbfβ-SMMHC via activation of MEK/ERK axis.

NrasG12D oncoprotein inhibits apoptosis of preleukemic cells expressing Cbfβ-SMMHC via activation of MEK/ERK axis.

http://www.wikidata.org/entity/Q33917204

about

Molecular Basis and Targeted Inhibition of CBFβ-SMMHC Acute Myeloid Leukemia.Chemical biology. A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice.Targeting binding partners of the CBFβ-SMMHC fusion protein for the treatment of inversion 16 acute myeloid leukemia.Mouse models for core binding factor leukemia.Mutant DNA methylation regulators endow hematopoietic stem cells with the preleukemic stem cell property, a requisite of leukemia initiation and relapse.MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia.Preleukemia and Leukemia-Initiating Cell Activity in inv(16) Acute Myeloid Leukemia.Pharmacological inhibition of aberrant transcription factor complexes in inversion 16 acute myeloid leukemia

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P2860

NrasG12D oncoprotein inhibits apoptosis of preleukemic cells expressing Cbfβ-SMMHC via activation of MEK/ERK axis.

http://www.wikidata.org/entity/Q33917204

description

2014 nî lūn-bûn

@nan

2014 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հունիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

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BLOOD-2013-12-541730

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NrasG12D oncoprotein inhibits ...... ia activation of MEK/ERK axis.

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P2093

John A Pulikkan

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Liting Xue

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Lucio H Castilla

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Peter J M Valk

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P2860

Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia

Implications of NRAS mutations in AML: a study of 2502 patients.

Inducible gene targeting in mice

The origin and evolution of mutations in acute myeloid leukemia

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

Identification of Lin(-)Sca1(+)kit(+)CD34(+)Flt3- short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients.

Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia.

Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras

Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia.

Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission

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426-436

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scholarly article

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10.1182/BLOOD-2013-12-541730

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3

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124

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2014-06-03T00:00:00Z

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24894773

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4102713

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