Expression and interdependencies of pluripotency factors LIN28, OCT3/4, NANOG and SOX2 in human testicular germ cells and tumours of the testis.
about
A gene expression profile of stem cell pluripotentiality and differentiation is conserved across diverse solid and hematopoietic cancersEtiology and early pathogenesis of malignant testicular germ cell tumors: towards possibilities for preinvasive diagnosismiRNA and mammalian male germ cellsLin28: primal regulator of growth and metabolism in stem cellsLin28 sustains early renal progenitors and induces Wilms tumorCross platform analysis of methylation, miRNA and stem cell gene expression data in germ cell tumors highlights characteristic differences by tumor histology.Dissecting the molecular pathways of (testicular) germ cell tumour pathogenesis; from initiation to treatment-resistance.Tumor-initiating cells are enriched in CD44(hi) population in murine salivary gland tumor.An integrated analysis of the SOX2 microRNA response program in human pluripotent and nullipotent stem cell lines.PIWI proteins are dispensable for mouse somatic development and reprogramming of fibroblasts into pluripotent stem cells.Lessons from human teratomas to guide development of safe stem cell therapies.Primordial germ cell development in the marmoset monkey as revealed by pluripotency factor expression: suggestion of a novel model of embryonic germ cell translocation.CK19 is a sensitive marker for yolk sac tumours of the testisBiology of childhood germ cell tumours, focussing on the significance of microRNAs.A genome-wide RNAi screen in mouse embryonic stem cells identifies Mp1 as a key mediator of differentiation.LIN28 cooperates with WNT signaling to drive invasive intestinal and colorectal adenocarcinoma in mice and humans.BMP Inhibition in Seminomas Initiates Acquisition of Pluripotency via NODAL Signaling Resulting in Reprogramming to an Embryonal CarcinomaAnalysis of LIN28A in early human ovary development and as a candidate gene for primary ovarian insufficiency.Nanog increases focal adhesion kinase (FAK) promoter activity and expression and directly binds to FAK protein to be phosphorylated.Lin-28 homologue A (LIN28A) promotes cell cycle progression via regulation of cyclin-dependent kinase 2 (CDK2), cyclin D1 (CCND1), and cell division cycle 25 homolog A (CDC25A) expression in cancerRapamycin increases oxidative stress response gene expression in adult stem cells.LIN28 is selectively expressed by primordial and pre-meiotic germ cells in the human fetal ovary.The pluripotency factor LIN28 in monkey and human testes: a marker for spermatogonial stem cells?MiR-208a stimulates the cocktail of SOX2 and β-catenin to inhibit the let-7 induction of self-renewal repression of breast cancer stem cells and formed miR208a/let-7 feedback loop via LIN28 and DICER1Testicular cancer and cryptorchidism.TRA-1-60(+), SSEA-4(+), POU5F1(+), SOX2(+), NANOG(+) Clones of Pluripotent Stem Cells in the Embryonal Carcinomas of the Testes.LIN28 Expression in malignant germ cell tumors downregulates let-7 and increases oncogene levelsTargeting cancer stem cells: emerging role of Nanog transcription factorLIN28 expression and prognostic value in hepatocellular carcinoma patients who meet the Milan criteria and undergo hepatectomy.Role of SOX2 in the etiology of embryonal carcinoma, based on analysis of the NCCIT and NT2 cell lines.Lin28a promotes self-renewal and proliferation of dairy goat spermatogonial stem cells (SSCs) through regulation of mTOR and PI3K/AKT.The rise of testicular germ cell tumours: the search for causes, risk factors and novel therapeutic targets.SOX2 is essential for in vivo reprogramming of seminoma-like TCam-2 cells to an embryonal carcinoma-like fate.Characterization and in vitro culture of putative spermatogonial stem cells derived from feline testicular tissue.A practical approach to immunohistochemical diagnosis of ovarian germ cell tumours and sex cord-stromal tumours.Characterization, isolation, and culture of mouse and human spermatogonial stem cells.NANOG: a promising target for digestive malignant tumorsCommon variants identified in genome-wide association studies of testicular germ cell tumour: an update, biological insights and clinical application.NANOG regulates epithelial-mesenchymal transition and chemoresistance through activation of the STAT3 pathway in epithelial ovarian cancer.Enhanced chemosensitivity by targeting Nanog in head and neck squamous cell carcinomas.
P2860
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P2860
Expression and interdependencies of pluripotency factors LIN28, OCT3/4, NANOG and SOX2 in human testicular germ cells and tumours of the testis.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Expression and interdependenci ...... lls and tumours of the testis.
@ast
Expression and interdependenci ...... lls and tumours of the testis.
@en
type
label
Expression and interdependenci ...... lls and tumours of the testis.
@ast
Expression and interdependenci ...... lls and tumours of the testis.
@en
prefLabel
Expression and interdependenci ...... lls and tumours of the testis.
@ast
Expression and interdependenci ...... lls and tumours of the testis.
@en
P2093
P2860
P1476
Expression and interdependenci ...... ells and tumours of the testis
@en
P2093
A J M Gillis
E Swartzman
J W Oosterhuis
K Biermann
R J H L M van Gurp
P2860
P304
P356
10.1111/J.1365-2605.2011.01148.X
P433
P577
2011-06-02T00:00:00Z