Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes. - Wikidata - wikimedia - TriplyDB

Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes.

Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes.

http://www.wikidata.org/entity/Q33920287

about

The PD-1 pathway in tolerance and autoimmunity The anticancer immune response of anti-PD-1/PD-L1 and the genetic determinants of response to anti-PD-1/PD-L1 antibodies in cancer patients Role of the PD-1 pathway in the immune response Risk factors and primary prevention trials for type 1 diabetes Chronic infection drives expression of the inhibitory receptor CD200R, and its ligand CD200, by mouse and human CD4 T cells The PD1:PD-L1/2 Pathway from Discovery to Clinical Implementation The Next Immune-Checkpoint Inhibitors: PD-1/PD-L1 Blockade in Melanoma The role of the PD-1 pathway in autoimmunity and peripheral tolerance PD-1 deficiency reveals various tissue-specific autoimmunity by H-2b and dose-dependent requirement of H-2g7 for diabetes in NOD mice.PD-1- and CTLA-4-based inhibitory chimeric antigen receptors (iCARs) divert off-target immunotherapy responses The role of co-inhibitory signals in spontaneous tolerance of weakly mismatched transplants Inflammatory cytokines compromise programmed cell death-1 (PD-1)-mediated T cell suppression in inflammatory arthritis through up-regulation of soluble PD-1.MSC-derived Extracellular Vesicles Attenuate Immune Responses in Two Autoimmune Murine Models: Type 1 Diabetes and Uveoretinitis.Meta-analysis of programmed cell death 1 polymorphisms with systemic lupus erythematosus risk Yin-Yang of costimulation: crucial controls of immune tolerance and function.PD-1, gender, and autoimmunity.Biochemical signaling of PD-1 on T cells and its functional implications Distinct genetic control of autoimmune neuropathy and diabetes in the non-obese diabetic background.Programmed cell death 1 (PD-1) regulates the effector function of CD8 T cells via PD-L1 expressed on target keratinocytes.Alteration of intra-pancreatic target-organ specificity by abrogation of Aire in NOD mice.PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice Role of PD-1 and its ligand, B7-H1, in early fate decisions of CD8 T cells Dendritic cell programming by cytomegalovirus stunts naive T cell responses via the PD-L1/PD-1 pathway.B7-1 mediated costimulation regulates pancreatic autoimmunity.Regulation of T cell activation and tolerance by PDL2 PD-L1-driven tolerance protects neurogenin3-induced islet neogenesis to reverse established type 1 diabetes in NOD mice.Blockade of the programmed death-1 (PD1) pathway undermines potent genetic protection from type 1 diabetes.The programmed death-1 ligand 1:B7-1 pathway restrains diabetogenic effector T cells in vivo Increased autoimmune diabetes in pIgR-deficient NOD mice is due to a "Hitchhiking" interval that refines the genetic effect of Idd5.4.Cutting edge: identification of autoreactive CD4+ and CD8+ T cell subsets resistant to PD-1 pathway blockade.PD-1 as an immune modulatory receptor.Association between PDCD1 Gene Polymorphisms and Risk of Systemic Lupus Erythematosus in Three Main Ethnic Groups of the Malaysian Population.Increased programmed death-1 expression on CD4+ T cells in cutaneous T-cell lymphoma: implications for immune suppression.Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity.Functional deficiencies of granulocyte-macrophage colony stimulating factor and interleukin-3 contribute to insulitis and destruction of beta cells.The role of coinhibitory signaling pathways in transplantation and tolerance IL-7 receptor blockade reverses autoimmune diabetes by promoting inhibition of effector/memory T cells.Expression of PD-1 Molecule on Regulatory T Lymphocytes in Patients with Insulin-Dependent Diabetes Mellitus.Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway.Tissue expression of PD-L1 mediates peripheral T cell tolerance.

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Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes.

http://www.wikidata.org/entity/Q33920287

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2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2005年の論文

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2005年論文

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2005年論文

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2005年论文

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Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes.

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Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes.

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Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes.

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Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes.

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Proceedings of the National Academy of Sciences of the United States of America

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Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes.

@en

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Hiroshi Hiai

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Jian Wang

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Taku Okazaki

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Taku Yoshida

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P2860

Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade.

The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor

Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice

Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cells

Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

Mapping autoimmunity genes.

Genetic dissection of systemic lupus erythematosus.

PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine.

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type-1 diabetes

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