Atypical PKCiota contributes to poor prognosis through loss of apical-basal polarity and cyclin E overexpression in ovarian cancer. - Wikidata - wikimedia - TriplyDB

Atypical PKCiota contributes to poor prognosis through loss of apical-basal polarity and cyclin E overexpression in ovarian cancer.

Atypical PKCiota contributes to poor prognosis through loss of apical-basal polarity and cyclin E overexpression in ovarian cancer.

http://www.wikidata.org/entity/Q33920769

about

Protein kinase C signaling and cell cycle regulation Overexpression of SnoN/SkiL, amplified at the 3q26.2 locus, in ovarian cancers: a role in ovarian pathogenesis Protein kinase C iota: human oncogene, prognostic marker and therapeutic target Emerging role of cell polarity proteins in breast cancer progression and metastasis Atypical protein kinase C induces cell transformation by disrupting Hippo/Yap signaling.Adenosine-binding motif mimicry and cellular effects of a thieno[2,3-d]pyrimidine-based chemical inhibitor of atypical protein kinase C isoenzymes Comprehensive molecular characterization of clear cell renal cell carcinoma.Asymmetric cell division of stem and progenitor cells during homeostasis and cancer The landscape of somatic copy-number alteration across human cancers.Loss of Par3 promotes breast cancer metastasis by compromising cell-cell cohesion.Coordination of glioblastoma cell motility by PKCι Scribble mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs.Scribble at the crossroads.The biology of ovarian cancer: new opportunities for translation Ovarian cancer: linking genomics to new target discovery and molecular markers--the way ahead.The guanine nucleotide exchange factor (GEF) Ect2 is an oncogene in human cancer.Genetic variability of the mTOR pathway and prostate cancer risk in the European Prospective Investigation on Cancer (EPIC).PKCλ/ι signaling promotes triple-negative breast cancer growth and metastasis Abortive autophagy induces endoplasmic reticulum stress and cell death in cancer cells.The F-box protein Slmb restricts the activity of aPKC to polarize epithelial cells Copy number gain of hsa-miR-569 at 3q26.2 leads to loss of TP53INP1 and aggressiveness of epithelial cancers.Regulation of glioblastoma cell invasion by PKC iota and RhoB.Protein kinase Cι expression and oncogenic signaling mechanisms in cancer.Identification of a small molecule with synthetic lethality for K-ras and protein kinase C iota A novel DAG-dependent mechanism links PKCɑ and Cyclin B1 regulating cell cycle progression.Protein kinase C zeta regulates human pancreatic cancer cell transformed growth and invasion through a STAT3-dependent mechanism Expression of polarity genes in human cancer.Atypical protein kinase C zeta: potential player in cell survival and cell migration of ovarian cancer.EVI1, a target gene for amplification at 3q26, antagonizes transforming growth factor-β-mediated growth inhibition in hepatocellular carcinoma.Vascular endothelial growth factor A as predictive marker for mTOR inhibition in relapsing high-grade serous ovarian cancer Partitioning-defective protein 6 (Par-6) activates atypical protein kinase C (aPKC) by pseudosubstrate displacement.Phosphorylation of claudin-4 by PKCepsilon regulates tight junction barrier function in ovarian cancer cells.A Drosophila Model of HPV E6-Induced Malignancy Reveals Essential Roles for Magi and the Insulin Receptor Expression of Par3 polarity protein correlates with poor prognosis in ovarian cancer PKCζ Promotes Breast Cancer Invasion by Regulating Expression of E-cadherin and Zonula Occludens-1 (ZO-1) via NFκB-p65.The Par complex and integrins direct asymmetric cell division in adult intestinal stem cells.PKCzeta at the crossroad of NF-kappaB and Jak1/Stat6 signaling pathways.Protein kinase Calpha and epsilon small-molecule targeted therapeutics: a new roadmap to two Holy Grails in drug discovery?Instructive role of aPKCzeta subcellular localization in the assembly of adherens junctions in neural progenitors.The chromosome 3q26 OncCassette: A multigenic driver of human cancer.

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P2860

Atypical PKCiota contributes to poor prognosis through loss of apical-basal polarity and cyclin E overexpression in ovarian cancer.

http://www.wikidata.org/entity/Q33920769

description

2005 nî lūn-bûn

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2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2005 թվականի օգոստոսին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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Atypical PKCiota contributes t ...... rexpression in ovarian cancer.

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Atypical PKCiota contributes t ...... rexpression in ovarian cancer.

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Atypical PKCiota contributes t ...... rexpression in ovarian cancer.

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Proceedings of the National Academy of Sciences of the United States of America

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Astrid M Eder

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Carla L Warneke

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Daniel G Rosen

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Edward N Atkinson

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Gordon B Mills

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Isabelle Bedrosian

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Jerry C P Yin

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Jinsong Liu

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Joe W Gray

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John P Lahad

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P2860

Segregation of receptor and ligand regulates activation of epithelial growth factor receptor

Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer

Nonparametric Estimation from Incomplete Observations

Epithelial-mesenchymal transitions in tumour progression

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines

High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays

Cancer statistics, 2005

Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia

Parsing the polarity code.

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