Discovery and characterization of inhibitors of human palmitoyl acyltransferases. - Wikidata - wikimedia - TriplyDB

Discovery and characterization of inhibitors of human palmitoyl acyltransferases.

Discovery and characterization of inhibitors of human palmitoyl acyltransferases.

http://www.wikidata.org/entity/Q33923711

about

Neurotensin receptor-1 inducible palmitoylation is required for efficient receptor-mediated mitogenic-signaling within structured membrane microdomains 2-Bromopalmitate and 2-(2-hydroxy-5-nitro-benzylidene)-benzo[b]thiophen-3-one inhibit DHHC-mediated palmitoylation in vitro The physiology of protein S-acylation 2-Bromopalmitate reduces protein deacylation by inhibition of acyl-protein thioesterase enzymatic activities Palmitoyl acyltransferase DHHC21 mediates endothelial dysfunction in systemic inflammatory response syndrome.Targeting protein lipidation in disease Ion channel regulation by protein S-acylation.Palmitoylation of oncogenic NRAS is essential for leukemogenesis.Protein Lipidation As a Regulator of Apoptotic Calcium Release: Relevance to Cancer.Palmitoylation: a protein S-acylation with implications for breast cancer.DHHC20: a human palmitoyl acyltransferase that causes cellular transformation Cellular palmitoylation and trafficking of lipidated peptides.Acylation in trypanosomatids: an essential process and potential drug target Palmitoyl acyltransferase assays and inhibitors (Review).Inhibition of Ras for cancer treatment: the search continues.Protein palmitoylation and pathogenesis in apicomplexan parasites.In vitro and cellular assays for palmitoyl acyltransferases using fluorescent lipidated peptides Fat chance! Getting a grip on a slippery modification.Palmitoylation of amyloid precursor protein regulates amyloidogenic processing in lipid rafts How to Target Activated Ras Proteins: Direct Inhibition vs. Induced Mislocalization.Palmitoyl acyltransferases, their substrates, and novel assays to connect them (Review).Click-Chemistry Based High Throughput Screening Platform for Modulators of Ras Palmitoylation.Ion channel regulation by protein palmitoylation.Exploring protein lipidation with chemical biology.Identification of targets and inhibitors of protein palmitoylation.Targeting protein palmitoylation: selective inhibitors and implications in disease.Dynamic protein S-palmitoylation mediates parasite life cycle progression and diverse mechanisms of virulence.Palmitoylation of interferon-alpha (IFN-alpha) receptor subunit IFNAR1 is required for the activation of Stat1 and Stat2 by IFN-alpha.cat-ELCCA: a robust method to monitor the fatty acid acyltransferase activity of ghrelin O-acyltransferase (GOAT).Protein Lipidation: Occurrence, Mechanisms, Biological Functions, and Enabling Technologies.Wogonoside induces depalmitoylation and translocation of PLSCR1 and N-RAS in primary acute myeloid leukaemia cells.Analysis of protein acylation.Treatment of Trypanosoma cruzi with 2-bromopalmitate alters morphology, endocytosis, differentiation and infectivity

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Discovery and characterization of inhibitors of human palmitoyl acyltransferases.

http://www.wikidata.org/entity/Q33923711

description

2006 nî lūn-bûn

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2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2006 թվականի հուլիսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Discovery and characterization of inhibitors of human palmitoyl acyltransferases.

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Discovery and characterization of inhibitors of human palmitoyl acyltransferases.

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Discovery and characterization of inhibitors of human palmitoyl acyltransferases.

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Discovery and characterization of inhibitors of human palmitoyl acyltransferases.

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Discovery and characterization of inhibitors of human palmitoyl acyltransferases.

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Discovery and characterization of inhibitors of human palmitoyl acyltransferases.

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1535-7163.MCT-06-0114

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Molecular Cancer Therapeutics

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Discovery and characterization of inhibitors of human palmitoyl acyltransferases.

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Charles D Smith

http://www.w3.org/2001/XMLSchema#string

Charles E Ducker

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John D Diller

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Lindsay K Griffel

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Ryan A Smith

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Staci N Keller

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Yan Zhuang

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Zuping Xia

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P2860

The DHHC domain: a new highly conserved cysteine-rich motif

DHHC9 and GCP16 constitute a human protein fatty acyltransferase with specificity for H- and N-Ras

Huntingtin-interacting protein HIP14 is a palmitoyl transferase involved in palmitoylation and trafficking of multiple neuronal proteins

Myristoylation and differential palmitoylation of the HCK protein-tyrosine kinases govern their attachment to membranes and association with caveolae

Huntingtin interacting protein 14 is an oncogenic human protein: palmitoyl acyltransferase

The yeast DHHC cysteine-rich domain protein Akr1p is a palmitoyl transferase

Functional rafts in cell membranes

Erf4p and Erf2p form an endoplasmic reticulum-associated complex involved in the plasma membrane localization of yeast Ras proteins.

A non-farnesylated Ha-Ras protein can be palmitoylated and trigger potent differentiation and transformation

5-Fluoroorotic acid as a selective agent in yeast molecular genetics

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