Poly(ADP-ribose) polymerase-dependent energy depletion occurs through inhibition of glycolysis. - Wikidata - wikimedia - TriplyDB

Poly(ADP-ribose) polymerase-dependent energy depletion occurs through inhibition of glycolysis.

Poly(ADP-ribose) polymerase-dependent energy depletion occurs through inhibition of glycolysis.

http://www.wikidata.org/entity/Q33925831

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DNA repair targeted therapy: The past or future of cancer treatment?Readers of poly(ADP-ribose): designed to be fit for purpose ARTD1 (PARP1) activation and NAD(+) in DNA repair and cell death Neuroprotective Strategies during Cardiac Surgery with Cardiopulmonary Bypass Analyzing structure-function relationships of artificial and cancer-associated PARP1 variants by reconstituting TALEN-generated HeLa PARP1 knock-out cells.Regulation of necrotic cell death: p53, PARP1 and cyclophilin D-overlapping pathways of regulated necrosis?Role of NAD+ and mitochondrial sirtuins in cardiac and renal diseases ARTD1/PARP1 negatively regulates glycolysis by inhibiting hexokinase 1 independent of NAD+ depletion.Inputs and outputs of poly(ADP-ribosyl)ation: Relevance to oxidative stress Aag-initiated base excision repair promotes ischemia reperfusion injury in liver, brain, and kidney.Differentiation-Associated Downregulation of Poly(ADP-Ribose) Polymerase-1 Expression in Myoblasts Serves to Increase Their Resistance to Oxidative Stress.NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus Selective dendritic susceptibility to bioenergetic, excitotoxic and redox perturbations in cortical neurons.Subcellular Distribution of NAD+ between Cytosol and Mitochondria Determines the Metabolic Profile of Human Cells.Tumor-selective use of DNA base excision repair inhibition in pancreatic cancer using the NQO1 bioactivatable drug, β-lapachone.Chemical signaling between gut microbiota and host chromatin: What is your gut really saying?Poly(ADP-ribose) polymerase 1 is a novel target to promote axonal regeneration.RhoA orchestrates glycolysis for TH2 cell differentiation and allergic airway inflammation.Poly-ADP-ribosylation-mediated degradation of ARTD1 by the NLRP3 inflammasome is a prerequisite for osteoclast maturation Poly(ADP-ribose) polymerase regulates glycolytic activity in kidney proximal tubule epithelial cells CTLA-4 Blockade Synergizes Therapeutically with PARP Inhibition in BRCA1-Deficient Ovarian Cancer.Metabolic regulation of histone post-translational modifications.Chemosensitivity of IDH1-Mutated Gliomas Due to an Impairment in PARP1-Mediated DNA Repair.Nicotinamide Adenine Dinucleotide Metabolism and Neurodegeneration.Poly(adenosine diphosphate-ribose) polymerase as therapeutic target: lessons learned from its inhibitors.S100B impairs glycolysis via enhanced poly(ADP-ribosyl)ation of glyceraldehyde-3-phosphate dehydrogenase in rodent muscle cells.Poly(ADP-ribosylated) proteins in mononuclear cells from patients with type 2 diabetes identified by proteomic studies.Generation of small molecules to interfere with regulated necrosis.The vicious circle of hypometabolism in neurodegenerative diseases: Ways and mechanisms of metabolic correction.New directions in poly(ADP-ribose) polymerase biology.Post-translational modifications in mitochondria: protein signaling in the powerhouse.The PARP family: insights into functional aspects of poly (ADP-ribose) polymerase-1 in cell growth and survival.NAMPT inhibition sensitizes pancreatic adenocarcinoma cells to tumor-selective, PAR-independent metabolic catastrophe and cell death induced by β-lapachone.Natural Compounds As Modulators of Non-apoptotic Cell Death in Cancer Cells.Ferroptosis: bug or feature?FAF1 mediates regulated necrosis through PARP1 activation upon oxidative stress leading to dopaminergic neurodegeneration Bioenergetic Impairment in Animal and Cellular Models of Alzheimer's Disease: PARP-1 Inhibition Rescues Metabolic Dysfunctions.Proteome-wide Profiling of Clinical PARP Inhibitors Reveals Compound-Specific Secondary Targets.At the Interface of Three Nucleic Acids: The Role of RNA-Binding Proteins and Poly(ADP-ribose) in DNA Repair.Mitochondrial Dysfunction Mediated by Poly(ADP-Ribose) Polymerase-1 Activation Contributes to Hippocampal Neuronal Damage Following Status Epilepticus.

P2860

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P2860

Poly(ADP-ribose) polymerase-dependent energy depletion occurs through inhibition of glycolysis.

http://www.wikidata.org/entity/Q33925831

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2014 nî lūn-bûn

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2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2014 թվականի հուլիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Poly(ADP-ribose) polymerase-de ...... ough inhibition of glycolysis.

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Poly(ADP-ribose) polymerase-de ...... ough inhibition of glycolysis.

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Poly(ADP-ribose) polymerase-de ...... ough inhibition of glycolysis.

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Proceedings of the National Academy of Sciences of the United States of America

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Poly(ADP-ribose) polymerase-de ...... ough inhibition of glycolysis.

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P2093

Calvin Chang

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Daniel A Stevens

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George K E Umanah

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Guy G Poirier

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Jean-Philippe Gagné

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Shaida A Andrabi

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P2860

Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease.

Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death

Amyloid-β triggers the release of neuronal hexokinase 1 from mitochondria

Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos)

Aerobic glycolysis: meeting the metabolic requirements of cell proliferation

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss.

Poly(ADP-ribose) polymerase impairs early and long-term experimental stroke recovery.

Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality.

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28

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111

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Valina L. Dawson

Senthilkumar S Karuppagounder

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2014-07-01T00:00:00Z

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24987120

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