Homologous recombination at c-fyn locus of mouse embryonic stem cells with use of diphtheria toxin A-fragment gene in negative selection. - Wikidata - wikimedia - TriplyDB

Homologous recombination at c-fyn locus of mouse embryonic stem cells with use of diphtheria toxin A-fragment gene in negative selection.

Homologous recombination at c-fyn locus of mouse embryonic stem cells with use of diphtheria toxin A-fragment gene in negative selection.

http://www.wikidata.org/entity/Q33927120

about

A conditional knockout resource for the genome-wide study of mouse gene function ABCA5 resides in lysosomes, and ABCA5 knockout mice develop lysosomal disease-like symptoms Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene Maspin is not required for embryonic development or tumour suppression MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation Embryonic lethality of molecular chaperone hsp47 knockout mice is associated with defects in collagen biosynthesis A novel transgenic chimaeric mouse system for the rapid functional evaluation of genes encoding secreted proteins.Gene targeting in mice: a review CEP290 alleles in mice disrupt tissue-specific cilia biogenesis and recapitulate features of syndromic ciliopathies Sarcoglycan isoforms in skeletal muscle Suppression of inflammatory and neuropathic pain symptoms in mice lacking the N-type Ca2+ channel.Mouse knock-out of IOP1 protein reveals its essential role in mammalian cytosolic iron-sulfur protein biogenesis The gamete fusion process is defective in eggs of Cd9-deficient mice Normal development of mice and unimpaired cell adhesion/cell motility/actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockout The mouse homolog of Drosophila Vasa is required for the development of male germ cells MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival G protein-coupled cholecystokinin-B/gastrin receptors are responsible for physiological cell growth of the stomach mucosa in vivo Biosynthetic processing of cathepsins and lysosomal degradation are abolished in asparaginyl endopeptidase-deficient mice Targeted disruption of the tyrosine hydroxylase locus results in severe catecholamine depletion and perinatal lethality in mice The murine ortholog of notchless, a direct regulator of the notch pathway in Drosophila melanogaster, is essential for survival of inner cell mass cells.Altered pain responses in mice lacking alpha 1E subunit of the voltage-dependent Ca2+ channel.A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice Multiple functional defects in peripheral autonomic organs in mice lacking muscarinic acetylcholine receptor gene for the M3 subtype Bcl11b is required for differentiation and survival of alphabeta T lymphocytes The transcription factor gene Nfib is essential for both lung maturation and brain development Impaired mitotic progression and preimplantation lethality in mice lacking OMCG1, a new evolutionarily conserved nuclear protein Loss of Bard1, the heterodimeric partner of the Brca1 tumor suppressor, results in early embryonic lethality and chromosomal instability Thalamic Cav3.1 T-type Ca2+ channel plays a crucial role in stabilizing sleep Underdeveloped uterus and reduced estrogen responsiveness in mice with disruption of the estrogen-responsive finger protein gene, which is a direct target of estrogen receptor alpha.Distinct and Cooperative Functions for the Protocadherin-α, -β and -γ Clusters in Neuronal Survival and Axon Targeting Metabolic phenotype of methylmalonic acidemia in mice and humans: the role of skeletal muscle Calpain 8/nCL-2 and calpain 9/nCL-4 constitute an active protease complex, G-calpain, involved in gastric mucosal defense.Mice lacking the metalloprotease-disintegrin MDC9 (ADAM9) have no evident major abnormalities during development or adult life.Simple monitoring of gene targeting efficiency in human somatic cell lines using the PIGA gene.Ig beta tyrosine residues contribute to the control of B cell receptor signaling by regulating receptor internalization.A novel strategy for the negative selection in mouse embryonic stem cells operated with immunotoxin-mediated cell targeting.Disruption of a conserved region of Xist exon 1 impairs Xist RNA localisation and X-linked gene silencing during random and imprinted X chromosome inactivation Creation and phenotypic analysis of alpha-lactalbumin-deficient mice Putative "stemness" gene jam-B is not required for maintenance of stem cell state in embryonic, neural, or hematopoietic stem cells.Potential role for ADAM15 in pathological neovascularization in mice.

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P2860

Homologous recombination at c-fyn locus of mouse embryonic stem cells with use of diphtheria toxin A-fragment gene in negative selection.

http://www.wikidata.org/entity/Q33927120

description

1990 nî lūn-bûn

@nan

1990 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1990 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

1990年の論文

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1990年学术文章

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1990年学术文章

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1990年学术文章

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1990年学术文章

@zh-my

1990年学术文章

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1990年學術文章

@yue

name

Homologous recombination at c- ...... nt gene in negative selection.

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Homologous recombination at c- ...... nt gene in negative selection.

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type

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Homologous recombination at c- ...... nt gene in negative selection.

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Homologous recombination at c- ...... nt gene in negative selection.

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prefLabel

Homologous recombination at c- ...... nt gene in negative selection.

@ast

Homologous recombination at c- ...... nt gene in negative selection.

@en

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PNAS.87.24.9918

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Homologous recombination at c- ...... nt gene in negative selection.

@en

P2093

Aizawa S

http://www.w3.org/2001/XMLSchema#string

Ikawa Y

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Mabuchi I

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Shigetani Y

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Takeda N

http://www.w3.org/2001/XMLSchema#string

Yagi T

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Yamamoto T

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Yoshida K

http://www.w3.org/2001/XMLSchema#string

P2860

DNA sequencing with chain-terminating inhibitors

yes-related protooncogene, syn, belongs to the protein-tyrosine kinase family

Diphtheria toxin

Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

Targeting of nonexpressed genes in embryonic stem cells via homologous recombination

HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells

Germ-line transmission of a disrupted beta 2-microglobulin gene produced by homologous recombination in embryonic stem cells

Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

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9918-9922

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24

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87

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20891715

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2263643

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55285

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