Homologous recombination at c-fyn locus of mouse embryonic stem cells with use of diphtheria toxin A-fragment gene in negative selection.
about
A conditional knockout resource for the genome-wide study of mouse gene functionABCA5 resides in lysosomes, and ABCA5 knockout mice develop lysosomal disease-like symptomsLoss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc geneMaspin is not required for embryonic development or tumour suppressionMicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocationEmbryonic lethality of molecular chaperone hsp47 knockout mice is associated with defects in collagen biosynthesisA novel transgenic chimaeric mouse system for the rapid functional evaluation of genes encoding secreted proteins.Gene targeting in mice: a reviewCEP290 alleles in mice disrupt tissue-specific cilia biogenesis and recapitulate features of syndromic ciliopathiesSarcoglycan isoforms in skeletal muscleSuppression of inflammatory and neuropathic pain symptoms in mice lacking the N-type Ca2+ channel.Mouse knock-out of IOP1 protein reveals its essential role in mammalian cytosolic iron-sulfur protein biogenesisThe gamete fusion process is defective in eggs of Cd9-deficient miceNormal development of mice and unimpaired cell adhesion/cell motility/actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockoutThe mouse homolog of Drosophila Vasa is required for the development of male germ cellsMyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survivalG protein-coupled cholecystokinin-B/gastrin receptors are responsible for physiological cell growth of the stomach mucosa in vivoBiosynthetic processing of cathepsins and lysosomal degradation are abolished in asparaginyl endopeptidase-deficient miceTargeted disruption of the tyrosine hydroxylase locus results in severe catecholamine depletion and perinatal lethality in miceThe murine ortholog of notchless, a direct regulator of the notch pathway in Drosophila melanogaster, is essential for survival of inner cell mass cells.Altered pain responses in mice lacking alpha 1E subunit of the voltage-dependent Ca2+ channel.A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in miceMultiple functional defects in peripheral autonomic organs in mice lacking muscarinic acetylcholine receptor gene for the M3 subtypeBcl11b is required for differentiation and survival of alphabeta T lymphocytesThe transcription factor gene Nfib is essential for both lung maturation and brain developmentImpaired mitotic progression and preimplantation lethality in mice lacking OMCG1, a new evolutionarily conserved nuclear proteinLoss of Bard1, the heterodimeric partner of the Brca1 tumor suppressor, results in early embryonic lethality and chromosomal instabilityThalamic Cav3.1 T-type Ca2+ channel plays a crucial role in stabilizing sleepUnderdeveloped uterus and reduced estrogen responsiveness in mice with disruption of the estrogen-responsive finger protein gene, which is a direct target of estrogen receptor alpha.Distinct and Cooperative Functions for the Protocadherin-α, -β and -γ Clusters in Neuronal Survival and Axon TargetingMetabolic phenotype of methylmalonic acidemia in mice and humans: the role of skeletal muscleCalpain 8/nCL-2 and calpain 9/nCL-4 constitute an active protease complex, G-calpain, involved in gastric mucosal defense.Mice lacking the metalloprotease-disintegrin MDC9 (ADAM9) have no evident major abnormalities during development or adult life.Simple monitoring of gene targeting efficiency in human somatic cell lines using the PIGA gene.Ig beta tyrosine residues contribute to the control of B cell receptor signaling by regulating receptor internalization.A novel strategy for the negative selection in mouse embryonic stem cells operated with immunotoxin-mediated cell targeting.Disruption of a conserved region of Xist exon 1 impairs Xist RNA localisation and X-linked gene silencing during random and imprinted X chromosome inactivationCreation and phenotypic analysis of alpha-lactalbumin-deficient micePutative "stemness" gene jam-B is not required for maintenance of stem cell state in embryonic, neural, or hematopoietic stem cells.Potential role for ADAM15 in pathological neovascularization in mice.
P2860
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P2860
Homologous recombination at c-fyn locus of mouse embryonic stem cells with use of diphtheria toxin A-fragment gene in negative selection.
description
1990 nî lūn-bûn
@nan
1990 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年学术文章
@wuu
1990年学术文章
@zh-cn
1990年学术文章
@zh-hans
1990年学术文章
@zh-my
1990年学术文章
@zh-sg
1990年學術文章
@yue
name
Homologous recombination at c- ...... nt gene in negative selection.
@ast
Homologous recombination at c- ...... nt gene in negative selection.
@en
type
label
Homologous recombination at c- ...... nt gene in negative selection.
@ast
Homologous recombination at c- ...... nt gene in negative selection.
@en
prefLabel
Homologous recombination at c- ...... nt gene in negative selection.
@ast
Homologous recombination at c- ...... nt gene in negative selection.
@en
P2093
P2860
P356
P1476
Homologous recombination at c- ...... nt gene in negative selection.
@en
P2093
Shigetani Y
Yamamoto T
P2860
P304
P356
10.1073/PNAS.87.24.9918
P407
P577
1990-12-01T00:00:00Z