High constitutive activity of native H3 receptors regulates histamine neurons in brain. - Wikidata - wikimedia - TriplyDB

High constitutive activity of native H3 receptors regulates histamine neurons in brain.

High constitutive activity of native H3 receptors regulates histamine neurons in brain.

http://www.wikidata.org/entity/Q33929208

about

Loss of constitutive activity of the growth hormone secretagogue receptor in familial short stature G protein-coupled receptors in the hypothalamic paraventricular and supraoptic nuclei--serpentine gateways to neuroendocrine homeostasis The histamine H3 receptor: an attractive target for the treatment of cognitive disorders Histamine and its receptors Acute wake-promoting actions of JNJ-5207852, a novel, diamine-based H3 antagonist Detection of multiple H3 receptor affinity states utilizing [3H]A-349821, a novel, selective, non-imidazole histamine H3 receptor inverse agonist radioligand Plasticity of histamine H3 receptor expression and binding in the vestibular nuclei after labyrinthectomy in rat Increased brain histamine H3 receptor expression during hibernation in golden-mantled ground squirrels Enhanced spontaneous activity of the mu opioid receptor by cysteine mutations: characterization of a tool for inverse agonist screening Histaminergic mechanisms for modulation of memory systems Phasic and Tonic mGlu7 Receptor Activity Modulates the Thalamocortical Network The Subcellular Dynamics of the Gs-Linked Receptor GPR3 Contribute to the Local Activation of PKA in Cerebellar Granular Neurons Two polymorphic forms of human histamine methyltransferase: structural, thermal, and kinetic comparisons Monoaminergic and Histaminergic Strategies and Treatments in Brain Diseases The cell biology of acute itch Constitutive activation of A(3) adenosine receptors by site-directed mutagenesis The role of carcinine in signaling at the Drosophila photoreceptor synapse Interactions between histamine H3 and dopamine D2 receptors and the implications for striatal function Genetic Analysis of Histamine Signaling in Larval Zebrafish Sleep.Identification of inhibitors of Plasmodium falciparum phosphoethanolamine methyltransferase using an enzyme-coupled transmethylation assay.The histaminergic system is involved in psychological stress-induced hyperthermia in rats.Structural basis for inhibition of histamine N-methyltransferase by diverse drugs Cannabinoid CB1 receptor-interacting proteins: novel targets for central nervous system drug discovery?H1-antihistamines: inverse agonism, anti-inflammatory actions and cardiac effects.Histamine in the regulation of wakefulness.BML-190 and AM251 act as inverse agonists at the human cannabinoid CB2 receptor: signalling via cAMP and inositol phosphates.Inverse agonism and its therapeutic significance.Protean agonism at histamine H3 receptors in vitro and in vivo The rat cytomegalovirus R33-encoded G protein-coupled receptor signals in a constitutive fashion Perspectives on cognitive domains, H3 receptor ligands and neurological disease.The histamine H3 receptor: from gene cloning to H3 receptor drugs.H3 receptors and pain modulation: peripheral, spinal, and brain interactions.Genetic variations in human G protein-coupled receptors: implications for drug therapy.Altered sleep-wake characteristics and lack of arousal response to H3 receptor antagonist in histamine H1 receptor knockout mice.Dimer-dependent intrinsic/basal activity of the class B G protein-coupled receptor PAC1 promotes cellular anti-apoptotic activity through Wnt/β-catenin pathways that are associated with dimer endocytosis The histamine H3 receptor: from discovery to clinical trials with pitolisant Homer as both a scaffold and transduction molecule.LC-MS/MS method for the determination of pitolisant: application to rat pharmacokinetic and brain penetration studies.G-protein-coupled receptors: past, present and future.Inverse agonists: tools to reveal ligand-specific conformations of G protein-coupled receptors.

P2860

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P2860

High constitutive activity of native H3 receptors regulates histamine neurons in brain.

http://www.wikidata.org/entity/Q33929208

description

2000 nî lūn-bûn

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2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2000年の論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年论文

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High constitutive activity of native H3 receptors regulates histamine neurons in brain.

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High constitutive activity of native H3 receptors regulates histamine neurons in brain.

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High constitutive activity of native H3 receptors regulates histamine neurons in brain.

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High constitutive activity of native H3 receptors regulates histamine neurons in brain.

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High constitutive activity of native H3 receptors regulates histamine neurons in brain.

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High constitutive activity of native H3 receptors regulates histamine neurons in brain.

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High constitutive activity of native H3 receptors regulates histamine neurons in brain

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Arrang JM

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Ganellin CR

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Gbahou F

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Morisset S

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Rouleau A

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Schunack W

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Schwartz JC

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Stark H

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Tardivel-Lacombe J

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P2860

Inverse agonism of histamine H2 antagonist accounts for upregulation of spontaneously active histamine H2 receptors

Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptor.

Highly potent and selective ligands for histamine H3-receptors.

Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the beta 2-adrenoceptor.

Multiple D2 dopamine receptors produced by alternative RNA splicing.

Reverse intrinsic activity of antagonists on G protein-coupled receptors.

Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas.

Evidence that histamine homologues discriminate between H3-receptors in guinea-pig cerebral cortex and ileum longitudinal muscle myenteric plexus

Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins.

Defects in G protein-coupled signal transduction in human disease.

P2888

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860-864

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10.1038/35048583

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