about
Membrane potentials regulating GPCRs: insights from experiments and molecular dynamics simulationsMolecular switches of the κ opioid receptor triggered by 6'-GNTI and 5'-GNTI.A Hydrogen-Bonded Polar Network in the Core of the Glucagon-Like Peptide-1 Receptor Is a Fulcrum for Biased Agonism: Lessons from Class B Crystal StructuresActivation mechanism of endothelin ETB receptor by endothelin-1Endogenous opioids contribute to insensitivity to pain in humans and mice lacking sodium channel Nav1.7Sequence, structure and ligand binding evolution of rhodopsin-like G protein-coupled receptors: a crystal structure-based phylogenetic analysisStructure and function of serotonin G protein-coupled receptors.Structural-Functional Features of the Thyrotropin Receptor: A Class A G-Protein-Coupled Receptor at WorkSeven perspectives on GPCR H/D-exchange proteomics methodsStructural heterogeneity of the μ-opioid receptor's conformational ensemble in the apo stateNative phasing of x-ray free-electron laser data for a G protein-coupled receptor.Mechanistic insights into the allosteric modulation of opioid receptors by sodium ions.Allosteric modulation of β-arrestin-biased angiotensin II type 1 receptor signaling by membrane stretch.Defining thermostability of membrane proteins by western blotting.The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled ReceptorDisruption of the Na+ ion binding site as a mechanism for positive allosteric modulation of the mu-opioid receptor.Allosteric effects of sodium ion binding on activation of the m3 muscarinic g-protein-coupled receptor.Buried ionizable networks are an ancient hallmark of G protein-coupled receptor activationStructure of the Angiotensin receptor revealed by serial femtosecond crystallography.Pharmacological Profile of Nociceptin/Orphanin FQ Receptors Interacting with G-Proteins and β-Arrestins 2.Eukaryotic G protein-coupled receptors as descendants of prokaryotic sodium-translocating rhodopsins.Receptor, Ligand and Transducer Contributions to Dopamine D2 Receptor Functional Selectivity.Structural dynamics and energetics underlying allosteric inactivation of the cannabinoid receptor CB1.Nucleotides Acting at P2Y Receptors: Connecting Structure and Function.Examining the Effects of Sodium Ions on the Binding of Antagonists to Dopamine D2 and D3 ReceptorsOpioid receptors: Structural and mechanistic insights into pharmacology and signaling.NMR structure and dynamics of the agonist dynorphin peptide bound to the human kappa opioid receptorPharmacophore-based virtual screening, biological evaluation and binding mode analysis of a novel protease-activated receptor 2 antagonist.Structural basis for selectivity and diversity in angiotensin II receptorsThe High-Resolution Structure of Activated Opsin Reveals a Conserved Solvent Network in the Transmembrane Region Essential for Activation.Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin ReceptorDREADDs for Neuroscientists.Nociceptin/Orphanin FQ Receptor Structure, Signaling, Ligands, Functions, and Interactions with Opioid Systems.Computational approaches to detect allosteric pathways in transmembrane molecular machines.Structural Mechanisms of Voltage Sensing in G Protein-Coupled ReceptorsNovel Analogues of (R)-5-(Methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Sumanirole) Provide Clues to Dopamine D2/D3 Receptor Agonist Selectivity.Functional and structural characterization of axonal opioid receptors as targets for analgesia.Structural basis for Na(+)-sensitivity in dopamine D2 and D3 receptorsStructural basis of ligand interaction with atypical chemokine receptor 3.Alternatively spliced mu opioid receptor C termini impact the diverse actions of morphine.
P2860
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P2860
description
2014 nî lūn-bûn
@nan
2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Allosteric sodium in class A GPCR signaling
@ast
Allosteric sodium in class A GPCR signaling
@en
type
label
Allosteric sodium in class A GPCR signaling
@ast
Allosteric sodium in class A GPCR signaling
@en
prefLabel
Allosteric sodium in class A GPCR signaling
@ast
Allosteric sodium in class A GPCR signaling
@en
P2093
P2860
P1476
Allosteric sodium in class A GPCR signaling
@en
P2093
Bryan L Roth
Enrique E Abola
Gustavo Fenalti
Vadim Cherezov
P2860
P304
P356
10.1016/J.TIBS.2014.03.002
P577
2014-04-21T00:00:00Z