Reovirus polypeptide sigma 3 and N-terminal myristoylation of polypeptide mu 1 are required for site-specific cleavage to mu 1C in transfected cells
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3.3 A cryo-EM structure of a nonenveloped virus reveals a priming mechanism for cell entry.Structure of the reovirus outer capsid and dsRNA-binding protein sigma3 at 1.8 A resolution.Structure of the reovirus membrane-penetration protein, Mu1, in a complex with is protector protein, Sigma3Determinants of strain-specific differences in efficiency of reovirus entryAdenovirus protein VI mediates membrane disruption following capsid disassembly.Features of reovirus outer capsid protein mu1 revealed by electron cryomicroscopy and image reconstruction of the virion at 7.0 Angstrom resolution.Sequence analysis of the genome of piscine orthoreovirus (PRV) associated with heart and skeletal muscle inflammation (HSMI) in Atlantic salmon (Salmo salar).Antibodies against outer-capsid proteins of grass carp reovirus expressed in E. coli are capable of neutralizing viral infectivity.Piscine Reovirus: Genomic and Molecular Phylogenetic Analysis from Farmed and Wild Salmonids Collected on the Canada/US Pacific Coast.Maturation of giardiavirus capsid protein involves posttranslational proteolytic processing by a cysteine proteaseAssociation of reovirus outer capsid proteins sigma 3 and mu 1 causes a conformational change that renders sigma 3 protease sensitive.Mutations in the zinc-binding motif of the reovirus capsid protein delta 3 eliminate its ability to associate with capsid protein mu 1.Early steps in reovirus infection are associated with dramatic changes in supramolecular structure and protein conformation: analysis of virions and subviral particles by cryoelectron microscopy and image reconstructionA carboxy-terminal fragment of protein mu 1/mu 1C is present in infectious subvirion particles of mammalian reoviruses and is proposed to have a role in penetrationTranslational stimulation by reovirus polypeptide sigma 3: substitution for VAI RNA and inhibition of phosphorylation of the alpha subunit of eukaryotic initiation factor 2.A positive-feedback mechanism promotes reovirus particle conversion to the intermediate associated with membrane penetration.Expression of virus-encoded proteinases: functional and structural similarities with cellular enzymesReovirus virion-like particles obtained by recoating infectious subvirion particles with baculovirus-expressed sigma3 protein: an approach for analyzing sigma3 functions during virus entry.In vitro recoating of reovirus cores with baculovirus-expressed outer-capsid proteins mu1 and sigma3.Intracellular posttranslational modifications of S1133 avian reovirus proteins.Regulated, stable expression and nuclear presence of reovirus double-stranded RNA-binding protein sigma3 in HeLa cells.Mutations in a CCHC zinc-binding motif of the reovirus sigma 3 protein decrease its intracellular stability.Reovirus outer capsid protein micro1 induces apoptosis and associates with lipid droplets, endoplasmic reticulum, and mitochondria.Folding and particle assembly are disrupted by single-point mutations near the autocatalytic cleavage site of Nudaurelia capensis omega virus capsid protein.Putative autocleavage of outer capsid protein micro1, allowing release of myristoylated peptide micro1N during particle uncoating, is critical for cell entry by reovirus.The VP4 peptide of hepatitis A virus ruptures membranes through formation of discrete pores.JAM-A-independent, antibody-mediated uptake of reovirus into cells leads to apoptosis.
P2860
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P2860
Reovirus polypeptide sigma 3 and N-terminal myristoylation of polypeptide mu 1 are required for site-specific cleavage to mu 1C in transfected cells
description
1992 nî lūn-bûn
@nan
1992 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1992年の論文
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1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Reovirus polypeptide sigma 3 a ...... to mu 1C in transfected cells
@ast
Reovirus polypeptide sigma 3 a ...... to mu 1C in transfected cells
@en
type
label
Reovirus polypeptide sigma 3 a ...... to mu 1C in transfected cells
@ast
Reovirus polypeptide sigma 3 a ...... to mu 1C in transfected cells
@en
prefLabel
Reovirus polypeptide sigma 3 a ...... to mu 1C in transfected cells
@ast
Reovirus polypeptide sigma 3 a ...... to mu 1C in transfected cells
@en
P2860
P1433
P1476
Reovirus polypeptide sigma 3 a ...... to mu 1C in transfected cells
@en
P2093
Shatkin AJ
Tillotson L
P2860
P304
P407
P577
1992-04-01T00:00:00Z