TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2. - Wikidata - wikimedia - TriplyDB

TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2.

TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2.

http://www.wikidata.org/entity/Q33931833

about

Ubiquitin-dependent regulation of Foxp3 and Treg function Treg functional stability and its responsiveness to the microenvironment The IL-17 pathway as a major therapeutic target in autoimmune diseases MicroRNA-21 promotes Th17 differentiation and mediates experimental autoimmune encephalomyelitis Ubiquitous points of control over regulatory T cells.1α,25-dihydroxyvitamin D3 in combination with transforming growth factor-β increases the frequency of Foxp3⁺ regulatory T cells through preferential expansion and usage of interleukin-2 TRAF6 mediates IL-1β/LPS-induced suppression of TGF-β signaling through its interaction with the type III TGF-β receptor.IL-18 synergizes with IL-7 to drive slow proliferation of naive CD8 T cells by costimulating self-peptide-mediated TCR signals.Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation.Ubiquitin makes its mark on immune regulation.Regulation of T cell receptor complex-mediated signaling by ubiquitin and ubiquitin-like modifications TRAF6 is essential for maintenance of regulatory T cells that suppress Th2 type autoimmunity Signal transduction pathways and transcriptional regulation in Th17 cell differentiation Phase I trial of adoptively transferred tumor-infiltrating lymphocyte immunotherapy following concurrent chemoradiotherapy in patients with locoregionally advanced nasopharyngeal carcinoma.IL-21 is an antitolerogenic cytokine of the late-phase alloimmune response.Longitudinal investigation of natural killer cells and cytokines in chronic fatigue syndrome/myalgic encephalomyelitis.Comprehensive evaluation of different T-helper cell subsets differentiation and function in rheumatoid arthritis.Dendritic cell expression of the signaling molecule TRAF6 is required for immune tolerance in the lung.Gene expression profiles associated with depression in patients with chronic hepatitis C (CH-C)TNFR-associated factor 6 regulates TCR signaling via interaction with and modification of LAT adapter TRAF molecules in cell signaling and in human diseases Smad4 in T cells plays a protective role in the development of autoimmune Sjögren's syndrome in the nonobese diabetic mouse.Direct and indirect regulatory mechanisms in TH17 cell differentiation and functions.Post-translational regulation of TGF-β receptor and Smad signaling.Tumor necrosis factor receptor- associated factor 6 (TRAF6) regulation of development, function, and homeostasis of the immune system.TNFR-Associated Factors 2 and 5 Differentially Regulate the Instructive IL-6 Receptor Signaling Required for Th17 Development.Inhibition of TGF-β signaling in genetically engineered tumor antigen-reactive T cells significantly enhances tumor treatment efficacy.The kinase PKCα selectively upregulates interleukin-17A during Th17 cell immune responses.CD4 T cell-intrinsic IL-2 signaling differentially affects Th1 and Th17 development.Immune Regulation by Ubiquitin Tagging as Checkpoint Code.The role of TGF-β in Th17 differentiation.TRAF molecules in inflammation and inflammatory diseases.TNF receptor-associated factor 6 in advanced non-small cell lung cancer: clinical and prognostic implications.Genetic Alterations of TRAF Proteins in Human Cancers Role of TRAFs in Signaling Pathways Controlling T Follicular Helper Cell Differentiation and T Cell-Dependent Antibody Responses

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P2860

TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2.

http://www.wikidata.org/entity/Q33931833

description

2010 nî lūn-bûn

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2010 թուականի Մարտին հրատարակուած գիտական յօդուած

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2010 թվականի մարտին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

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2010年论文

@wuu

name

TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2.

@ast

TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2.

@en

type

label

TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2.

@ast

TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2.

@en

prefLabel

TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2.

@ast

TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2.

@en

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P1476

TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2.

@en

P2093

Daehee Han

http://www.w3.org/2001/XMLSchema#string

David Artis

http://www.w3.org/2001/XMLSchema#string

Erika L Pearce

http://www.w3.org/2001/XMLSchema#string

Gretchen M Harms

http://www.w3.org/2001/XMLSchema#string

Laurence A Turka

http://www.w3.org/2001/XMLSchema#string

Matthew C Walsh

http://www.w3.org/2001/XMLSchema#string

Pedro J Cejas

http://www.w3.org/2001/XMLSchema#string

Yongwon Choi

http://www.w3.org/2001/XMLSchema#string

P2860

The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

Tob is a negative regulator of activation that is expressed in anergic and quiescent T cells

Transforming growth factor-beta induces development of the T(H)17 lineage

TH17 cells in development: an updated view of their molecular identity and genetic programming

Characteristics and biological functions of TRAF6

Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation

IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells

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