TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2.
about
Ubiquitin-dependent regulation of Foxp3 and Treg functionTreg functional stability and its responsiveness to the microenvironmentThe IL-17 pathway as a major therapeutic target in autoimmune diseasesMicroRNA-21 promotes Th17 differentiation and mediates experimental autoimmune encephalomyelitisUbiquitous points of control over regulatory T cells.1α,25-dihydroxyvitamin D3 in combination with transforming growth factor-β increases the frequency of Foxp3⁺ regulatory T cells through preferential expansion and usage of interleukin-2TRAF6 mediates IL-1β/LPS-induced suppression of TGF-β signaling through its interaction with the type III TGF-β receptor.IL-18 synergizes with IL-7 to drive slow proliferation of naive CD8 T cells by costimulating self-peptide-mediated TCR signals.Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation.Ubiquitin makes its mark on immune regulation.Regulation of T cell receptor complex-mediated signaling by ubiquitin and ubiquitin-like modificationsTRAF6 is essential for maintenance of regulatory T cells that suppress Th2 type autoimmunitySignal transduction pathways and transcriptional regulation in Th17 cell differentiationPhase I trial of adoptively transferred tumor-infiltrating lymphocyte immunotherapy following concurrent chemoradiotherapy in patients with locoregionally advanced nasopharyngeal carcinoma.IL-21 is an antitolerogenic cytokine of the late-phase alloimmune response.Longitudinal investigation of natural killer cells and cytokines in chronic fatigue syndrome/myalgic encephalomyelitis.Comprehensive evaluation of different T-helper cell subsets differentiation and function in rheumatoid arthritis.Dendritic cell expression of the signaling molecule TRAF6 is required for immune tolerance in the lung.Gene expression profiles associated with depression in patients with chronic hepatitis C (CH-C)TNFR-associated factor 6 regulates TCR signaling via interaction with and modification of LAT adapterTRAF molecules in cell signaling and in human diseasesSmad4 in T cells plays a protective role in the development of autoimmune Sjögren's syndrome in the nonobese diabetic mouse.Direct and indirect regulatory mechanisms in TH17 cell differentiation and functions.Post-translational regulation of TGF-β receptor and Smad signaling.Tumor necrosis factor receptor- associated factor 6 (TRAF6) regulation of development, function, and homeostasis of the immune system.TNFR-Associated Factors 2 and 5 Differentially Regulate the Instructive IL-6 Receptor Signaling Required for Th17 Development.Inhibition of TGF-β signaling in genetically engineered tumor antigen-reactive T cells significantly enhances tumor treatment efficacy.The kinase PKCα selectively upregulates interleukin-17A during Th17 cell immune responses.CD4 T cell-intrinsic IL-2 signaling differentially affects Th1 and Th17 development.Immune Regulation by Ubiquitin Tagging as Checkpoint Code.The role of TGF-β in Th17 differentiation.TRAF molecules in inflammation and inflammatory diseases.TNF receptor-associated factor 6 in advanced non-small cell lung cancer: clinical and prognostic implications.Genetic Alterations of TRAF Proteins in Human CancersRole of TRAFs in Signaling Pathways Controlling T Follicular Helper Cell Differentiation and T Cell-Dependent Antibody Responses
P2860
Q26863525-63F34060-0D41-4A26-B919-BBA16462AE8AQ27008946-C3CDD300-F3D6-42B5-967E-D77642648EAAQ28300826-5B659386-3E57-419A-AEB7-36E9D4125EE4Q28975627-469A0F6E-1B2A-4BC3-99BD-5C1D7A551DE4Q33850593-FC2A0838-F834-40AB-A94B-4B1FD23BE11DQ34065797-78E3446F-F737-4B1D-9182-F32DE3EB0106Q34199975-C6C4EA74-BFA1-4967-958F-FA1A9BCC33BBQ34289372-1CCEFB35-23C3-458A-A37B-ACDD3733135EQ34421833-AC1E1BFC-1B30-4AC3-8BB8-29242A6BA9E3Q34539820-841D42B1-C979-4448-84FD-F83A68EF982CQ34987659-3870FE20-4317-4309-B946-2846FB942C32Q34994847-23F9C025-A43B-4120-9EDF-1F3AAABA334FQ35238480-E5C9E36C-B17F-4DF8-B938-F4B135391528Q35507358-255FD17E-E69F-4DA7-85A2-E65BBFCE4510Q35561097-9499D03E-F11B-47AA-9297-7B68F88F57E5Q36298951-FDC79D11-7926-4E2D-B1AA-F6B406254BF5Q36311556-DB1EE0A8-9677-4C8A-8647-1C87C41BFE6CQ36321884-B3C9F95A-11C1-477B-BCE2-61B0B2FE5B91Q36373495-F8BE876B-C3E7-475A-B38D-868EC77490A0Q36754365-733060FC-F957-4055-BA37-A771C8109A07Q36972287-BD9385DC-C1AC-4D55-99B6-2C8C42990F02Q37696996-FCC57F00-9C07-46D7-84BE-64558DAF6141Q37977126-D31B22AD-1512-4719-AEED-FF86DF245F4EQ38012228-CA33FDAE-3D3E-49C0-A749-280639A2174AQ38530619-0E5EBE2B-F728-4F18-93AF-9032D3D2116EQ38778362-F1DA3D25-1153-4386-8FDD-A3EB0B79CF51Q39280062-C8500F3A-59AC-4DFD-BCBC-404D06276EF9Q43031049-B7D0F2C5-27E6-4D9C-B479-C274BB11F2B6Q46311944-BC12DE75-604C-40DE-9418-176462618297Q47774246-2AB0815D-E204-458B-A13A-03799F29BD51Q52570914-7EBEB2A6-2AF6-4372-8F3E-AA9FCF4A9B0EQ52661592-ED1C076C-099C-4B28-83E9-A6F9143C1A85Q53160550-8C7841FF-CCA5-4010-A63C-630C3037EBA2Q57191736-531E150E-20AA-4D3D-92A0-4BB8F1539BDDQ58580426-9DF75A03-068B-4374-828B-CEE59D5FBF26
P2860
TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2.
@ast
TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2.
@en
type
label
TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2.
@ast
TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2.
@en
prefLabel
TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2.
@ast
TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2.
@en
P2093
P2860
P1433
P1476
TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2.
@en
P2093
Daehee Han
David Artis
Erika L Pearce
Gretchen M Harms
Laurence A Turka
Matthew C Walsh
Pedro J Cejas
Yongwon Choi
P2860
P304
P356
10.1182/BLOOD-2009-09-242768
P407
P577
2010-03-29T00:00:00Z