2-Methoxyestradiol: an endogenous antiangiogenic and antiproliferative drug candidate. - Wikidata - wikimedia - TriplyDB

2-Methoxyestradiol: an endogenous antiangiogenic and antiproliferative drug candidate.

2-Methoxyestradiol: an endogenous antiangiogenic and antiproliferative drug candidate.

http://www.wikidata.org/entity/Q33934075

about

Opposite regulation of XIAP and Smac/DIABLO in the rat endometrium in response to 17beta-estradiol at estrus Crystal structure of human sex hormone-binding globulin in complex with 2-methoxyestradiol reveals the molecular basis for high affinity interactions with C-2 derivatives of estradiol Involvement of reactive oxygen species in 2-methoxyestradiol-induced apoptosis in human neuroblastoma cells 2-Methoxyestradiol, a promising anticancer agent Photodynamic therapy of a 2-methoxyestradiol tumor-targeting drug delivery system mediated by Asn-Gly-Arg in breast cancer.Natural product-based inhibitors of hypoxia-inducible factor-1 (HIF-1).Double-stranded RNA-dependent protein kinase is involved in 2-methoxyestradiol-mediated cell death of osteosarcoma cells.Disease modifying and antiangiogenic activity of 2-methoxyestradiol in a murine model of rheumatoid arthritis.2-Methoxyestradiol-bis-sulfamate induces apoptosis and autophagy in a tumorigenic breast epithelial cell line.Effects of estrogen metabolite 2-methoxyestradiol on tumor suppressor protein p53 and proliferation of breast cancer cells.Anticancer drug 2-methoxyestradiol protects against renal ischemia/reperfusion injury by reducing inflammatory cytokines expression Regulation of interferon pathway in 2-methoxyestradiol-treated osteosarcoma cells.O-methylation of catechol estrogens by human placental catechol-o-methyltransferase: interindividual differences in sensitivity to heat inactivation and to inhibition by dietary polyphenols.Urinary estrogen metabolites and prostate cancer risk: a pilot study.Negative regulation of the endocytic adaptor disabled-2 (Dab2) in mitosis.Combination of albendazole and 2-methoxyestradiol significantly improves the survival of HCT-116 tumor-bearing nude mice.Therapeutic promises of 2-methoxyestradiol and its drug disposition challenges Sulphamoylated 2-methoxyestradiol analogues induce apoptosis in adenocarcinoma cell lines.Molecular targets in the inhibition of angiogenesis.Sex-specific differences in hyperoxic lung injury in mice: role of cytochrome P450 (CYP)1A.Induction of the intrinsic apoptotic pathway via a new antimitotic agent in an esophageal carcinoma cell line Effect of tumour necrosis factor-alpha on estrogen metabolic pathways in breast cancer cells.2-Methoxyestradiol inhibits experimental autoimmune encephalomyelitis through suppression of immune cell activation The therapeutic potential of a series of orally bioavailable anti-angiogenic microtubule disruptors as therapy for hormone-independent prostate and breast cancers.Assessing the regioselectivity of OleD-catalyzed glycosylation with a diverse set of acceptors.2-Methoxyestradiol Alleviates Experimental Autoimmune Uveitis by Inhibiting Lymphocytes Proliferation and T Cell Differentiation.HIF-1alpha inhibition ameliorates neonatal brain injury in a rat pup hypoxic-ischemic model.Inhibition of human catechol-O-methyltransferase (COMT)-mediated O-methylation of catechol estrogens by major polyphenolic components present in coffee.Critical role of cyclin B1/Cdc2 up-regulation in the induction of mitotic prometaphase arrest in human breast cancer cells treated with 2-methoxyestradiol.The Bone Sparing Effects of 2-Methoxyestradiol Are Mediated via Estrogen Receptor-α in Male Mice.2-methoxyestradiol attenuates bleomycin-induced pulmonary hypertension and fibrosis in estrogen-deficient rats.2-methoxyestradiol binding of GPR30 down-regulates angiotensin AT(1) receptor.Inhibition of VEGF receptors significantly impairs mammary cancer growth in C3(1)/Tag transgenic mice through antiangiogenic and non-antiangiogenic mechanisms.Novel combination of 2-methoxyestradiol and cyclophosphamide enhances the antineoplastic and pro-apoptotic effects on S-180 ascitic tumour cells.2-Methoxyestradiol enhances radiosensitivity in radioresistant melanoma MDA-MB-435R cells by regulating glycolysis via HIF-1α/PDK1 axis.Impact of ER520, a candidate of selective estrogen receptor modulators, on in vitro cell growth, migration, invasion, angiogenesis and in vivo tumor xenograft of human breast cancer cells.Hydrogel-PLGA delivery system prolongs 2-methoxyestradiol-mediated anti-tumor effects in osteosarcoma cells.Increased COMT expression in pancreatic cancer and correlation with clinicopathologic parameters.2-Methoxyestradiol induced Bax phosphorylation and apoptosis in human retinoblastoma cells via p38 MAPK activation.The in vitro effects of 2-methoxyestradiol-bis-sulphamate on cell numbers, membrane integrity and cell morphology, and the possible induction of apoptosis and autophagy in a non-tumorigenic breast epithelial cell line.

P2860

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P2860

2-Methoxyestradiol: an endogenous antiangiogenic and antiproliferative drug candidate.

http://www.wikidata.org/entity/Q33934075

description

2000 nî lūn-bûn

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2000 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2000 թվականի հունվարին հրատարակված գիտական հոդված

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2000年の論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年论文

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name

2-Methoxyestradiol: an endogenous antiangiogenic and antiproliferative drug candidate.

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2-Methoxyestradiol: an endogenous antiangiogenic and antiproliferative drug candidate.

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2-Methoxyestradiol: an endogenous antiangiogenic and antiproliferative drug candidate.

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2-Methoxyestradiol: an endogenous antiangiogenic and antiproliferative drug candidate.

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2-Methoxyestradiol: an endogenous antiangiogenic and antiproliferative drug candidate.

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2-Methoxyestradiol: an endogenous antiangiogenic and antiproliferative drug candidate.

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