Development of a gene therapy virus with a glucocorticoid-inducible MMP1 for the treatment of steroid glaucoma.
about
Extracellular matrix in the trabecular meshwork: intraocular pressure regulation and dysregulation in glaucomaCystatin a, a potential common link for mutant myocilin causative glaucomaUp-regulated expression of extracellular matrix remodeling genes in phagocytically challenged trabecular meshwork cellsTissue plasminogen activator in trabecular meshwork attenuates steroid induced outflow resistance in mice.Treatment of sheep steroid-induced ocular hypertension with a glucocorticoid-inducible MMP1 gene therapy virusGlaucoma: genes, phenotypes, and new directions for therapy.Glycyrrhizin could reduce ocular hypertension induced by triamcinolone acetonide in rabbits.Cytoskeletal dependence of adenosine triphosphate release by human trabecular meshwork cellsMapping molecular differences and extracellular matrix gene expression in segmental outflow pathways of the human ocular trabecular meshwork.Capsid Mutated Adeno-Associated Virus Delivered to the Anterior Chamber Results in Efficient Transduction of Trabecular Meshwork in Mouse and RatMethods for gene transfer to the central nervous system.Aberrant Collagen Composition of the Trabecular Meshwork Results in Reduced Aqueous Humor Drainage and Elevated IOP in MMP-9 Null Mice.The autophagic lysosomal system in outflow pathway physiology and pathophysiology.Inducible scAAV2.GRE.MMP1 lowers IOP long-term in a large animal model for steroid-induced glaucoma gene therapy.Advances in glaucoma treatment and management: outflow drugs.Gene therapy strategies in glaucoma and application for steroid-induced hypertensionDevelopment of a model of elevated intraocular pressure in rats by gene transfer of bone morphogenetic protein 2.Medical treatment of glaucoma: present and future.Discovery of Molecular Therapeutics for Glaucoma: Challenges, Successes, and Promising Directions.Gene transfer to the outflow tract.Steroid-induced ocular hypertension/glaucoma: Focus on pharmacogenomics and implications for precision medicine.Cathepsin B is up-regulated and mediates extracellular matrix degradation in trabecular meshwork cells following phagocytic challenge.Open-angle glaucoma: therapeutically targeting the extracellular matrix of the conventional outflow pathway.
P2860
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P2860
Development of a gene therapy virus with a glucocorticoid-inducible MMP1 for the treatment of steroid glaucoma.
description
2010 nî lūn-bûn
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2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年學術文章
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name
Development of a gene therapy ...... treatment of steroid glaucoma.
@ast
Development of a gene therapy ...... treatment of steroid glaucoma.
@en
type
label
Development of a gene therapy ...... treatment of steroid glaucoma.
@ast
Development of a gene therapy ...... treatment of steroid glaucoma.
@en
prefLabel
Development of a gene therapy ...... treatment of steroid glaucoma.
@ast
Development of a gene therapy ...... treatment of steroid glaucoma.
@en
P2860
P356
P1476
Development of a gene therapy ...... treatment of steroid glaucoma.
@en
P2093
Maria-Grazia Spiga
Teresa Borrás
P2860
P304
P356
10.1167/IOVS.09-4918
P407
P577
2010-01-20T00:00:00Z