Identification of a pre-S2 mutant in hepatocytes expressing a novel marginal pattern of surface antigen in advanced diseases of chronic hepatitis B virus infection.
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Different types of ground glass hepatocytes in chronic hepatitis B virus infection contain specific pre-S mutants that may induce endoplasmic reticulum stressModulation of the unfolded protein response by the human hepatitis B virusInduction of Bcl-2 expression by hepatitis B virus pre-S2 mutant large surface protein resistance to 5-fluorouracil treatment in Huh-7 cellsHepatitis B virus PreS2-mutant large surface antigen activates store-operated calcium entry and promotes chromosome instabilityHepatitis B virus pre-S deletion mutations are a risk factor for hepatocellular carcinoma: a matched nested case-control study.Transgenic expression of entire hepatitis B virus in mice induces hepatocarcinogenesis independent of chronic liver injuryCoexistence of hepatitis B virus quasispecies enhances viral replication and the ability to induce host antibody and cellular immune responses.Induction of apurinic endonuclease 1 overexpression by endoplasmic reticulum stress in hepatoma cells.The emerging role of hepatitis B virus pre-S2 deletion mutant proteins in HBV tumorigenesis.High prevalence of hepatitis B virus pre-s mutant in countries where it is endemic and its relationship with genotype and chronicityHBsAg inhibits the translocation of JTB into mitochondria in HepG2 cells and potentially plays a role in HCC progression.Hepatitis B Virus-Related Hepatocellular Carcinoma: Pathogenic Mechanisms and Novel Therapeutic Interventions.Hepatitis B virus pre-S mutants, endoplasmic reticulum stress and hepatocarcinogenesis.The N-Glycosylation Modification of LHBs (Large Surface Proteins of HBV) Effects on Endoplasmic Reticulum Stress, Cell Proliferation and its Secretion.Zinc-dependent interaction between JAB1 and pre-S2 mutant large surface antigen of hepatitis B virus and its implications for viral hepatocarcinogenesis.A pre-S gene chip to detect pre-S deletions in hepatitis B virus large surface antigen as a predictive marker for hepatoma risk in chronic hepatitis B virus carriers.Different Mechanisms May Exist for HBsAg Synthesis and Secretion During Various Phases of Chronic Hepatitis B Virus Infection.Hepatocellular carcinoma: the point of view of the hepatitis B virus.Broad spectrum of hepatocyte inclusions in humans, animals, and experimental models.Novel autoregulatory function of hepatitis B virus M protein on surface gene expression.Pre-S2 Mutant-Induced Mammalian Target of Rapamycin Signal Pathways as Potential Therapeutic Targets for Hepatitis B Virus-Associated Hepatocellular Carcinoma.Enhanced expression of vascular endothelial growth factor-A in ground glass hepatocytes and its implication in hepatitis B virus hepatocarcinogenesis.Genomic change in hepatitis B virus associated with development of hepatocellular carcinoma.Pre-S mutations of hepatitis B virus affect genome replication and expression of surface antigens.Overlapping gene mutations of hepatitis B virus in a chronic hepatitis B patient with hepatitis B surface antigen loss during lamivudine therapyHistone deacetylase inhibitor suberoylanilide hydroxamic acid suppresses the pro-oncogenic effects induced by hepatitis B virus pre-S2 mutant oncoprotein and represents a potential chemopreventive agent in high-risk chronic HBV patients.
P2860
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P2860
Identification of a pre-S2 mutant in hepatocytes expressing a novel marginal pattern of surface antigen in advanced diseases of chronic hepatitis B virus infection.
description
2000 nî lūn-bûn
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2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2000 թվականի մայիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
@zh-hant
2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Identification of a pre-S2 mut ...... c hepatitis B virus infection.
@ast
Identification of a pre-S2 mut ...... c hepatitis B virus infection.
@en
type
label
Identification of a pre-S2 mut ...... c hepatitis B virus infection.
@ast
Identification of a pre-S2 mut ...... c hepatitis B virus infection.
@en
prefLabel
Identification of a pre-S2 mut ...... c hepatitis B virus infection.
@ast
Identification of a pre-S2 mut ...... c hepatitis B virus infection.
@en
P2093
P2860
P1476
Identification of a pre-S2 mut ...... c hepatitis B virus infection.
@en
P2093
P2860
P304
P356
10.1046/J.1440-1746.2000.02187.X
P577
2000-05-01T00:00:00Z