Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver.
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Is Liver Enzyme Release Really Associated with Cell Necrosis Induced by Oxidant Stress?Keap1/Nrf2 pathway in the frontiers of cancer and non-cancer cell metabolismMultiple roles of Nrf2-Keap1 signaling: regulation of development and xenobiotic response using distinct mechanismsMechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative diseaseEffect of graded Nrf2 activation on phase-I and -II drug metabolizing enzymes and transporters in mouse liverProteomics indicators of the rapidly shifting physiology from whole mountain pine beetle, Dendroctonus ponderosae (Coleoptera: Curculionidae), adults during early host colonizationNrf2 deficiency in myeloid cells is not sufficient to protect mice from high-fat diet-induced adipose tissue inflammation and insulin resistance.Chronic Activation of Hepatic Nrf2 Has No Major Effect on Fatty Acid and Glucose Metabolism in Adult MiceIdentification and quantification of the basal and inducible Nrf2-dependent proteomes in mouse liver: biochemical, pharmacological and toxicological implicationsSex differences in the acute in vivo effects of different human SP-A variants on the mouse alveolar macrophage proteome.Nrf2 affects the efficiency of mitochondrial fatty acid oxidation.Genetic activation of Nrf2 protects against fasting-induced oxidative stress in livers of mice.The role of the antioxidant and longevity-promoting Nrf2 pathway in metabolic regulation.New insight into the molecular drug target of diabetic nephropathy.Beneficial role of Nrf2 in regulating NADPH generation and consumption.Total proteome analysis identifies migration defects as a major pathogenetic factor in immunoglobulin heavy chain variable region (IGHV)-unmutated chronic lymphocytic leukemia.In vivo rescue of alveolar macrophages from SP-A knockout mice with exogenous SP-A nearly restores a wild type intracellular proteome; actin involvement.iTRAQ-based quantitative proteomic analysis of longissimus muscle from growing pigs with dietary supplementation of non-starch polysaccharide enzymes.Hydrogen sulfide in biochemistry and medicine.Integrated transcriptomic and proteomic analyses uncover regulatory roles of Nrf2 in the kidney.Nrf2 deficiency improves glucose tolerance in mice fed a high-fat dietTranscriptomic and proteomic profiling of KEAP1 disrupted and sulforaphane-treated human breast epithelial cells reveals common expression profiles.Sex differences in the response of the alveolar macrophage proteome to treatment with exogenous surfactant protein-A.New player on an old field; the keap1/Nrf2 pathway as a target for treatment of type 2 diabetes and metabolic syndrome.Green tea extract provides extensive Nrf2-independent protection against lipid accumulation and NFκB pro- inflammatory responses during nonalcoholic steatohepatitis in mice fed a high-fat diet.Hepatic gene expression profiling in Nrf2 knockout mice after long-term high-fat diet-induced obesityDrug metabolism alterations in nonalcoholic fatty liver diseaseNovel Grb14-Mediated Cross Talk between Insulin and p62/Nrf2 Pathways Regulates Liver Lipogenesis and Selective Insulin Resistance.Proteome changes in the small intestinal mucosa of growing pigs with dietary supplementation of non-starch polysaccharide enzymes.Molecular mechanisms of hypolipidemic effects of curcumin.The role of the Nrf2/Keap1 pathway in obesity and metabolic syndrome.The emerging role of Nrf2 in mitochondrial functionThe Dual Role of Nrf2 in Nonalcoholic Fatty Liver Disease: Regulation of Antioxidant Defenses and Hepatic Lipid Metabolism.p62/SQSTM1-Dr. Jekyll and Mr. Hyde that prevents oxidative stress but promotes liver cancer.WNT-3A regulates an Axin1/NRF2 complex that regulates antioxidant metabolism in hepatocytes.Role of nuclear factor (erythroid-derived 2)-like 2 in metabolic homeostasis and insulin action: A novel opportunity for diabetes treatment?Broccoli sprout extract induces detoxification-related gene expression and attenuates acute liver injury.In vivo siRNA delivery of Keap1 modulates death and survival signaling pathways and attenuates concanavalin-A-induced acute liver injury in mice.Ischemic Preconditioning Protects Astrocytes against Oxygen Glucose Deprivation Via the Nuclear Erythroid 2-Related Factor 2 Pathway.Real-time in vivo imaging reveals localised Nrf2 stress responses associated with direct and metabolism-dependent drug toxicity.
P2860
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P2860
Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver.
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Proteomic analysis of Nrf2 def ...... pendent pathways in the liver.
@ast
Proteomic analysis of Nrf2 def ...... pendent pathways in the liver.
@en
type
label
Proteomic analysis of Nrf2 def ...... pendent pathways in the liver.
@ast
Proteomic analysis of Nrf2 def ...... pendent pathways in the liver.
@en
prefLabel
Proteomic analysis of Nrf2 def ...... pendent pathways in the liver.
@ast
Proteomic analysis of Nrf2 def ...... pendent pathways in the liver.
@en
P2093
P2860
P50
P1476
Proteomic analysis of Nrf2 def ...... ependent pathways in the liver
@en
P2093
Azman Abdullah
B Kevin Park
Christopher E P Goldring
Christopher Sanderson
Helen Powell
Larry Higgins
Masayuki Yamamoto
Neil R Kitteringham
Rowena Sison
Samantha Williams
P2860
P304
P356
10.1016/J.JPROT.2010.03.018
P577
2010-04-24T00:00:00Z