Molecular cloning and functional characterization of MCH2, a novel human MCH receptor. - Wikidata - wikimedia - TriplyDB

Molecular cloning and functional characterization of MCH2, a novel human MCH receptor.

Molecular cloning and functional characterization of MCH2, a novel human MCH receptor.

http://www.wikidata.org/entity/Q33939968

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Brain regulation of energy balance and body weight.Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive, and hyperphagic and have altered metabolism The role of melanin-concentrating hormone and its receptors in energy homeostasis The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors Conformational features of human melanin-concentrating hormone: an NMR and computational analysis.Periplakin interferes with G protein activation by the melanin-concentrating hormone receptor-1 by binding to the proximal segment of the receptor C-terminal tail.The Melanin-Concentrating Hormone as an Integrative Peptide Driving Motivated Behaviors Meta-analysis of melanin-concentrating hormone signaling-deficient mice on behavioral and metabolic phenotypes Identification and pharmacological characterization of a novel human melanin-concentrating hormone receptor, mch-r2.Synthesis and biological evaluation in vitro of a selective, high potency peptide agonist of human melanin-concentrating hormone action at human melanin-concentrating hormone receptor 1.Antidepressant, anxiolytic and anorectic effects of a melanin-concentrating hormone-1 receptor antagonist.Human immune cells express ppMCH mRNA and functional MCHR1 receptor.Does the melanin-concentrating hormone antagonist SNAP-7941 deserve 3As?Evaluation of AMG 076, a potent and selective MCHR1 antagonist, in rodent and primate obesity models Melanin-concentrating hormone receptor mutations and human obesity: functional analysis.Identification and characterization of single-nucleotide polymorphisms in MCH-R1 and MCH-R2.Pmch-deficiency in rats is associated with normal adipocyte differentiation and lower sympathetic adipose drive.Melanin-concentrating hormone: a new sleep factor?Novel G-protein-coupled receptor genes expressed in the brain: continued discovery of important therapeutic targets.New insights into the binding mode of melanin concentrating hormone receptor-1 antagonists: homology modeling and explicit membrane molecular dynamics simulation study Melanin-concentrating hormone neuron system: the Wide Web that controls the feeding.Intestinal upregulation of melanin-concentrating hormone in TNBS-induced enterocolitis in adult zebrafish.Peptides and their potential role in the treatment of diabetes and obesity.Therapeutic potential of melanin-concentrating hormone-1 receptor antagonists for the treatment of obesity.Human Th2 cells selectively express the orexigenic peptide, pro-melanin-concentrating hormone.Characterization of two melanin-concentrating hormone genes in zebrafish reveals evolutionary and physiological links with the mammalian MCH system.[¹⁸F]FE@SNAP-A new PET tracer for the melanin concentrating hormone receptor 1 (MCHR1): microfluidic and vessel-based approaches Melanin-concentrating hormone as a mediator of intestinal inflammation.The melanin-concentrating hormone receptors: neuronal and non-neuronal functions.Orphan GPCR research.Preparation and First Preclinical Evaluation of [(18)F]FE@SNAP: A Potential PET Tracer for the Melanin-Concentrating Hormone Receptor-1 (MCHR1)Control of ventricular ciliary beating by the melanin concentrating hormone-expressing neurons of the lateral hypothalamus: a functional imaging survey.MCH receptors/gene structure-in vivo expression.Recent updates on the melanin-concentrating hormone (MCH) and its receptor system: lessons from MCH1R antagonists.Cellular models for the study of the pharmacology and signaling of melanin-concentrating hormone receptors.Discovery and development of melanin-concentrating hormone receptor 1 antagonists for the treatment of obesity.Regulated Control of Melanin-Concentrating Hormone Receptor 1 through Posttranslational Modifications.The MCH(1) receptor, an anti-obesity target, is allosterically inhibited by 8-methylquinoline derivatives possessing subnanomolar binding and long residence times.Different structural requirements for melanin-concentrating hormone (MCH) interacting with rat MCH-R1 (SLC-1) and mouse B16 cell MCH-R.In vivo evaluation of radiotracers targeting the melanin-concentrating hormone receptor 1: [11C]SNAP-7941 and [18F]FE@SNAP reveal specific uptake in the ventricular system.

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Molecular cloning and functional characterization of MCH2, a novel human MCH receptor.

http://www.wikidata.org/entity/Q33939968

description

2001 nî lūn-bûn

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2001 թուականի Մարտին հրատարակուած գիտական յօդուած

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2001 թվականի մարտին հրատարակված գիտական հոդված

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2001年論文

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2001年論文

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Molecular cloning and functional characterization of MCH2, a novel human MCH receptor.

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Molecular cloning and functional characterization of MCH2, a novel human MCH receptor.

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type

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Molecular cloning and functional characterization of MCH2, a novel human MCH receptor.

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Molecular cloning and functional characterization of MCH2, a novel human MCH receptor.

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Molecular cloning and functional characterization of MCH2, a novel human MCH receptor.

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Molecular cloning and functional characterization of MCH2, a novel human MCH receptor.

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Journal of Biological Chemistry

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Molecular cloning and functional characterization of MCH2, a novel human MCH receptor.

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Ames RS

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Bergsma DJ

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Chambers JK

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Duckworth M

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Gloger IS

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Hill J

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Levy DS

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Muir AI

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Murdock P

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Rennie G

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P2860

Melanin-concentrating hormone is the cognate ligand for the orphan G-protein-coupled receptor SLC-1

Molecular characterization of the melanin-concentrating-hormone receptor

Neuromedin U is a potent agonist at the orphan G protein-coupled receptor FM3

Arrestin binding to the G protein-coupled N-formyl peptide receptor is regulated by the conserved "DRY" sequence

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Cloning, localisation and functional expression of a novel human, cerebellum specific, two pore domain potassium channel

Isolation and characterization of the human melanin-concentrating hormone gene and a variant gene

The receptor for the orexigenic peptide melanin-concentrating hormone is a G-protein-coupled receptor

Cloning of the rat brain cDNA encoding for the SLC-1 G protein-coupled receptor reveals the presence of an intron in the gene.

Constitutive activation of the delta opioid receptor by mutations in transmembrane domains III and VII.

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20125-20129

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10.1074/JBC.M102068200

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23

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276

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11274220

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